2-Thiopheneacetic acid, a derivative of thiophene, holds significance in everyday life due to its diverse applications in pharmaceuticals and agrochemicals. It is commonly utilized as an intermediate in the synthesis of various drugs and pesticides, contributing to the advancement of medical treatments and agricultural practices. Its presence in these sectors underscores its importance in improving human health and food production, making it a valuable compound in both industrial and everyday settings.
Table of Contents:
- 💡 Commercial Applications
- ⚗️ Chemical & Physical Properties
- 🏭 Production & Procurement
- ⚠️ Safety Considerations
- 🔬 Potential Research Directions
- 🧪 Related Compounds
💡 Commercial Applications
2-Thiopheneacetic acid, also known as thiophene-2-acetic acid, has several commercial and industrial applications. It is commonly used as a building block in the synthesis of various pharmaceuticals and agrochemicals. Additionally, it is utilized in the production of flavors and fragrances due to its unique odor profile.
In the realm of drug and medication applications, 2-Thiopheneacetic acid plays a vital role as a key intermediate in the synthesis of several important drugs. It is used in the production of a variety of pharmaceuticals, including antipsychotic medications, anticonvulsants, and anti-inflammatory drugs. Due to its versatile chemical structure, it is able to facilitate the creation of complex molecules necessary for these therapeutic purposes.
⚗️ Chemical & Physical Properties
2-Thiopheneacetic acid is a white crystalline solid with a pungent odor, reminiscent of sulfur. The compound is readily soluble in organic solvents such as ethanol and acetone.
With a molar mass of 150.2 g/mol and a density of 1.374 g/cm3, 2-Thiopheneacetic acid is heavier than common food items such as sugar (molar mass of 342.3 g/mol, density of 0.80 g/cm3) and salt (molar mass of 58.44 g/mol, density of 2.16 g/cm3).
The melting point of 2-Thiopheneacetic acid is 94-96°C, while its boiling point is 230-235°C. In comparison, common food items like butter and chocolate have lower melting and boiling points, making 2-Thiopheneacetic acid more heat resistant.
2-Thiopheneacetic acid has limited solubility in water, forming a cloudy suspension, and exhibits low viscosity. This is in stark contrast to common food items like sugar and salt, which dissolve readily in water and have a higher viscosity.
🏭 Production & Procurement
2-Thiopheneacetic acid is typically produced through a series of chemical reactions involving thiophene. The process begins with the chlorination of thiophene to form 2-chlorothiophene, which is then treated with potassium acetate to yield 2-Thiopheneacetic acid.
2-Thiopheneacetic acid can be procured from chemical suppliers specializing in organic acids. It is often available in both liquid and powder forms, depending on the application requirements. The product can be transported in sealed containers to prevent spills or contamination during transit.
Transportation of 2-Thiopheneacetic acid is usually carried out by specialized chemical transport companies equipped to handle hazardous materials. The product is packaged according to regulatory guidelines and transported in compliance with safety protocols to ensure minimal risk of exposure or environmental harm. It is essential to follow proper handling procedures to prevent any accidents or incidents during transport.
⚠️ Safety Considerations
Safety considerations for 2-Thiopheneacetic acid include the potential for skin and eye irritation upon contact. Proper personal protective equipment, such as gloves and goggles, should be worn when handling this compound. In addition, 2-Thiopheneacetic acid should be stored in a cool, dry place away from sources of ignition to prevent fire hazards.
Hazard statements for 2-Thiopheneacetic acid include “Causes skin irritation” and “Causes serious eye irritation.” These statements indicate the potential for harm when this compound comes into contact with skin or eyes. It is important to handle 2-Thiopheneacetic acid with caution and follow proper safety protocols to prevent injury.
Precautionary statements for 2-Thiopheneacetic acid include “Wear protective gloves/protective clothing/eye protection/face protection” and “IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.” These statements emphasize the importance of using appropriate personal protective equipment and taking immediate action in case of exposure to 2-Thiopheneacetic acid. It is crucial to follow these precautions to minimize the risk of harm.
🔬 Potential Research Directions
2-Thiopheneacetic acid, a heterocyclic compound, offers a rich landscape for potential research directions. One avenue of study could involve its potential use as a building block in the synthesis of other heterocyclic compounds with biological activity. Another area of interest could be investigating the relationship between the structure of 2-Thiopheneacetic acid and its reactivity in various chemical reactions.
Researchers may also choose to explore the pharmacological properties of 2-Thiopheneacetic acid and its derivatives. This could involve studying its potential as a drug candidate for treating various diseases or conditions. Additionally, investigations into the potential toxicological effects of 2-Thiopheneacetic acid could offer valuable insights into its safety profile and potential risks associated with its use in pharmaceuticals or other applications.
Moreover, the development of new synthetic methods for the preparation of 2-Thiopheneacetic acid and its derivatives could be a fruitful research direction. These methods could focus on improving the efficiency, scalability, and sustainability of the synthesis process. Furthermore, exploring the potential applications of 2-Thiopheneacetic acid in materials science, such as in the development of new polymers or sensors, could open up new avenues for innovation and discovery in this field.
🧪 Related Compounds
One similar compound to 2-Thiopheneacetic acid is 2-Thiophenecarboxylic acid. This compound has a molecular structure similar to 2-Thiopheneacetic acid but with a carboxylic acid group instead of an acetic acid group. The presence of the carboxylic acid group allows for different chemical interactions and properties compared to 2-Thiopheneacetic acid.
Another similar compound is 2-Thiophenemethanol. This compound also shares a similar molecular structure with 2-Thiopheneacetic acid, but with a hydroxyl group attached instead of an acetic acid group. The presence of the hydroxyl group can lead to different reactivity and biological activity compared to 2-Thiopheneacetic acid.
A third similar compound is 2-Thiophenemethylamine. This compound has a similar molecular structure to 2-Thiopheneacetic acid, but with an amine group instead of an acetic acid group. The presence of the amine group can significantly alter the chemical reactivity and properties of the compound compared to 2-Thiopheneacetic acid.
