2-Phenylbutyramide, a chemical compound often used as a treatment for uremic pruritus in chronic kidney disease patients, may seem distant from everyday life to the average consumer. However, its relevance lies in its potential to improve the quality of life for individuals suffering from this debilitating condition. By alleviating itching and discomfort associated with uremic pruritus, 2-Phenylbutyramide offers tangible relief to those grappling with the challenges of chronic kidney disease, thereby underscoring its importance in enhancing daily well-being and comfort.
Table of Contents:
- 💡 Commercial Applications
- ⚗️ Chemical & Physical Properties
- 🏭 Production & Procurement
- ⚠️ Safety Considerations
- 🔬 Potential Research Directions
- 🧪 Related Compounds
💡 Commercial Applications
2-Phenylbutyramide, also known as beta-phenylbutyramide, has a variety of commercial and industrial applications. It is commonly used as an intermediate in the synthesis of pharmaceuticals, agrochemicals, and fragrances. Additionally, it can be used as a corrosion inhibitor in various industrial applications due to its ability to protect metal surfaces from degradation.
In the realm of drug and medication applications, 2-Phenylbutyramide has shown promise as a potential treatment for certain neurological disorders. Research has indicated that this compound may have neuroprotective effects and could potentially be used in the development of drugs for conditions such as Parkinson’s disease and Alzheimer’s disease. Further studies are needed to fully understand the therapeutic potential of 2-Phenylbutyramide in the field of medicine.
⚗️ Chemical & Physical Properties
2-Phenylbutyramide is a crystalline solid that appears as colorless to off-white in appearance. It has a faint, pleasant odor that is described as similar to almond or cherry.
With a molar mass of 165.21 g/mol and a density of 1.031 g/cm³, 2-Phenylbutyramide is relatively light compared to common food items. For example, sugar has a molar mass of 342.30 g/mol and a density of 1.59 g/cm³, making it heavier and denser than 2-Phenylbutyramide.
The melting point of 2-Phenylbutyramide is approximately 76-78°C, while its boiling point is around 283-285°C. These values are lower compared to common food items like sugar, which has a melting point of 186°C and a boiling point of 368°C.
2-Phenylbutyramide is sparingly soluble in water and exhibits low viscosity. In comparison to common food items, such as salt which is highly soluble in water and has a higher viscosity, 2-Phenylbutyramide shows limited solubility and lower viscosity in aqueous solutions.
🏭 Production & Procurement
2-Phenylbutyramide, also known as phenylbutyramide or 2-phenylbutyric acid amide, is typically produced through a chemical synthesis process. This involves reacting phenylbutyric acid with an appropriate amine compound, such as ammonia or an amine derivative, under controlled conditions. The reaction yields 2-Phenylbutyramide as the final product, which can then be further purified and processed for various industrial or research applications.
In terms of procurement, 2-Phenylbutyramide can be acquired through chemical suppliers or manufacturers specializing in fine chemicals and pharmaceutical intermediates. These suppliers often offer the compound in different forms, such as powder or crystals, with varying levels of purity. Transporting 2-Phenylbutyramide typically involves packaging the compound in suitable containers that meet regulatory requirements for safe handling and shipping. Depending on the quantity and destination, shipping methods may include ground transport, air freight, or sea freight to ensure timely and secure delivery to the end user.
For researchers or industries requiring 2-Phenylbutyramide in larger quantities or customized formulations, it is advisable to establish direct relationships with reliable suppliers or manufacturers. This allows for better control over product quality, pricing, and availability, as well as the possibility of requesting specific modifications or packaging options to meet specific project requirements. Additionally, it is important to adhere to all legal and safety regulations governing the handling, storage, and disposal of 2-Phenylbutyramide to ensure compliance with industry standards and environmental regulations.
⚠️ Safety Considerations
Safety considerations for 2-Phenylbutyramide should include the following: It should be handled with care to avoid skin and eye irritation. It should be stored in a cool, dry place away from heat and sources of ignition. Proper ventilation should be maintained when working with this compound to avoid inhalation of vapors. Protective equipment such as gloves, goggles, and lab coat should be worn when handling 2-Phenylbutyramide to minimize exposure.
The hazard statements for 2-Phenylbutyramide include: Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation. Harmful if swallowed. Harmful if inhaled. May cause damage to organs through prolonged or repeated exposure. May cause allergy or asthma symptoms or breathing difficulties if inhaled.
Precautionary statements for 2-Phenylbutyramide should include: Wear protective gloves, eye protection, and face protection. Avoid breathing vapors, mist, or spray. Wash thoroughly after handling. Use only outdoors or in a well-ventilated area. Do not eat, drink, or smoke while using this product. Store in a well-ventilated place. Keep container tightly closed. Dispose of contents/container in accordance with local regulations.
🔬 Potential Research Directions
One potential research direction for 2-Phenylbutyramide is its use as a potential therapeutic agent in the treatment of various medical conditions. Studies could investigate its efficacy in reducing inflammation, alleviating pain, or modulating immune responses.
Another research direction could focus on the pharmacokinetics and metabolism of 2-Phenylbutyramide in the human body. Understanding how this compound is absorbed, distributed, metabolized, and excreted could provide valuable insights into its potential side effects, optimal dosing regimens, and overall safety profile.
Furthermore, research could explore the mechanisms of action of 2-Phenylbutyramide at the molecular level. Investigating how this compound interacts with specific biological targets or signaling pathways could elucidate its potential therapeutic effects and help identify new drug targets for the development of novel treatments.
🧪 Related Compounds
One similar compound to 2-Phenylbutyramide is 2-Phenylpropionamide, also known as beta-phenylpropionamide. This compound has a similar molecular structure to 2-Phenylbutyramide, with a phenyl group attached to a propionamide backbone. 2-Phenylpropionamide is commonly used in the synthesis of pharmaceuticals and research chemicals due to its stable structure and diverse properties.
Another compound that shares similarities with 2-Phenylbutyramide is N-Ethyl-2-phenylbutyramide. This compound has an ethyl group attached to the nitrogen atom of the butyramide backbone, similar to the phenyl group in 2-Phenylbutyramide. N-Ethyl-2-phenylbutyramide is often used in the pharmaceutical industry as a precursor for various drugs and active pharmaceutical ingredients.
One more compound with a comparable structure to 2-Phenylbutyramide is 2-Phenylpentanamide, also known as valerylphenylamide. Like 2-Phenylbutyramide, this compound contains a phenyl group attached to a pentanamide backbone. 2-Phenylpentanamide is commonly used in organic synthesis and drug research due to its unique chemical properties and potential pharmaceutical applications.
