2-Phenyl-2-propanol, a common fragrance ingredient found in perfumes and cosmetics, plays a significant role in everyday life. Its pleasant, floral scent is used to enhance the fragrance of various consumer products, adding to the overall sensory experience of individuals in their daily routines. Additionally, 2-Phenyl-2-propanol is utilized in the pharmaceutical industry as a key component in the synthesis of certain medications. Overall, the presence of this compound in everyday products highlights its relevance and impact on our daily lives.
Table of Contents:
- 💡 Commercial Applications
- ⚗️ Chemical & Physical Properties
- 🏭 Production & Procurement
- ⚠️ Safety Considerations
- 🔬 Potential Research Directions
- 🧪 Related Compounds
💡 Commercial Applications
2-Phenyl-2-propanol, also known as α-methylbenzyl alcohol, is commonly used in fragrances and perfumes due to its pleasant aroma. It is also utilized in the production of flavors, as well as in the synthesis of pharmaceuticals and agrochemicals.
In the industrial sector, 2-Phenyl-2-propanol serves as a useful intermediate in the manufacturing of various chemicals, such as antioxidants, plasticizers, and UV stabilizers. Its ability to act as a solvent and a stabilizer makes it valuable in the production of paints, coatings, and adhesives.
In the realm of pharmaceuticals, 2-Phenyl-2-propanol is employed as a chiral auxiliary in asymmetric synthesis to produce enantiomerically pure compounds. It is also utilized in the synthesis of certain medications, such as antihistamines and antifungal agents, due to its potential biological activity. Additionally, this compound has shown promise in the development of novel drug delivery systems.
⚗️ Chemical & Physical Properties
2-Phenyl-2-propanol is a colorless liquid with a pleasant floral odor. Its appearance resembles that of water.
The molar mass of 2-Phenyl-2-propanol is approximately 150.22 g/mol, and its density is around 0.98 g/cm³. This places it in the range of common food items such as sugar (180 g/mol, 1.59 g/cm³) and salt (58.44 g/mol, 2.16 g/cm³) in terms of molar mass and density.
The melting point of 2-Phenyl-2-propanol is around -70°C, while its boiling point is approximately 214°C. This differs significantly from common food items such as butter (melting point: 32-35°C, boiling point: 177°C) and olive oil (melting point: -6 to -3°C, boiling point: 160-240°C).
2-Phenyl-2-propanol is slightly soluble in water, forming a clear solution. It has a relatively low viscosity, making it easier to mix with other substances. In comparison, common food items like sugar and salt are highly soluble in water and have varying levels of viscosity.
🏭 Production & Procurement
2-Phenyl-2-propanol, also known as alpha-methylbenzyl alcohol, is primarily produced through the reaction of benzyl chloride with acetone. This reaction typically takes place in the presence of a base catalyst, such as sodium hydroxide, at elevated temperatures. The resulting product is then purified through distillation to obtain the desired 2-Phenyl-2-propanol.
The procurement of 2-Phenyl-2-propanol can be achieved through chemical suppliers or manufacturers that specialize in producing aromatic compounds. Once procured, the compound is typically packaged in drums or containers for easy transportation. Given its relatively stable nature, 2-Phenyl-2-propanol can be safely transported via road, rail, or air depending on the quantity and destination. Additionally, proper labeling and documentation are essential for compliance with transportation regulations.
⚠️ Safety Considerations
Safety considerations for 2-Phenyl-2-propanol include its flammability and potential skin and eye irritation. It is important to handle this chemical in a well-ventilated area to prevent inhalation of vapors. Personal protective equipment, such as gloves and safety goggles, should be worn when working with 2-Phenyl-2-propanol to minimize the risk of exposure to the skin and eyes.
Hazard statements for 2-Phenyl-2-propanol include “Causes skin irritation” and “Causes serious eye irritation.” These statements indicate that direct contact with this chemical can lead to irritation of the skin and eyes. It is important to take appropriate safety precautions, such as wearing protective gloves and goggles, when handling 2-Phenyl-2-propanol to reduce the risk of adverse effects on the skin and eyes.
Precautionary statements for 2-Phenyl-2-propanol include “Avoid breathing vapors, mist, or spray” and “Wash hands and any exposed skin thoroughly after handling.” These statements emphasize the importance of minimizing inhalation of this chemical and practicing good personal hygiene to prevent skin exposure. It is essential to follow these precautionary measures to ensure safe handling and storage of 2-Phenyl-2-propanol in a laboratory or industrial setting.
🔬 Potential Research Directions
One potential research direction for 2-Phenyl-2-propanol is its use as a chiral auxiliary in asymmetric synthesis reactions. This compound has shown promise in creating enantiomerically pure products, making it an interesting molecule to explore in the development of new methodologies in organic chemistry.
Another area of research interest could be the investigation of the pharmacological properties of 2-Phenyl-2-propanol. Studies have suggested that this compound may have anti-inflammatory and analgesic effects, which could warrant further exploration in the realm of drug development. Understanding the molecular mechanisms underlying these potential therapeutic benefits could open up new avenues for pharmaceutical research.
🧪 Related Compounds
One similar compound to 2-Phenyl-2-propanol based upon molecular structure is 1-Phenyl-2-propanol. This compound also contains a phenyl group attached to a propanol chain, but in this case, the phenyl group is located at the first carbon of the propanol chain. This subtle difference in the placement of the phenyl group can result in variations in the compound’s physical and chemical properties.
Another similar compound to 2-Phenyl-2-propanol is 2-Phenylethanol. This compound has a similar molecular structure, with a phenyl group attached to an ethanol chain. The primary difference between 2-Phenyl-2-propanol and 2-Phenylethanol is the length of the carbon chain to which the phenyl group is attached. This difference can impact the compound’s solubility, reactivity, and other properties.
Additionally, another similar compound to 2-Phenyl-2-propanol is 1-Phenyl-1-propanol. Like 2-Phenyl-2-propanol, this compound contains a phenyl group attached to a propanol chain. However, in this case, the phenyl group is located on the first carbon of the propanol chain. This slight structural variation can lead to differences in the compound’s behavior in various chemical reactions and interactions with other compounds.