2-Oxoarginine

2-Oxoarginine is a compound that plays a significant role in various biochemical processes in the human body. It is particularly relevant in the field of medicine, as it is involved in the production of nitric oxide, a signaling molecule that helps regulate blood pressure and immune response. Additionally, 2-Oxoarginine has been linked to certain diseases and conditions, making it an important factor in the study and treatment of various health issues. Its relevance extends to everyday life as it contributes to our overall understanding of human physiology and the development of medical treatments.

Table of Contents:

💡 Commercial Applications

2-Oxoarginine, an intermediate compound in the urea cycle, has limited commercial and industrial applications. It is not commonly utilized in manufacturing processes or commercial products due to its primarily biological significance in the body.

In the field of pharmaceuticals, 2-Oxoarginine has potential drug and medication applications. Research has shown that it may play a role in promoting wound healing and reducing inflammation. However, further studies are needed to fully understand its therapeutic benefits and potential uses in medical treatments.

Overall, the commercial and industrial applications of 2-Oxoarginine are currently limited. While it may have potential in the pharmaceutical industry for developing new drugs and medications, its use outside of the biological realm remains largely unexplored. Further research and studies are necessary to determine its full range of applications and benefits.

⚗️ Chemical & Physical Properties

2-Oxoarginine is a white crystalline powder with no distinct odor.

It has a molar mass of approximately 175.19 g/mol and a density of 1.383 g/cm3. Compared to common household items, 2-Oxoarginine has a lower molar mass but a higher density than table salt.

The melting point of 2-Oxoarginine is around 282°C, while its boiling point is approximately 584°C. In comparison, these values are higher than that of water but lower than that of iron.

2-Oxoarginine is moderately soluble in water and has a moderate viscosity. This differs from common household items like sugar, which is highly soluble in water but exhibits a similar viscosity.

🏭 Production & Procurement

2-Oxoarginine, a non-proteinogenic amino acid, can be produced through chemical synthesis in a laboratory setting. This process typically involves the reaction of arginine with an oxidizing agent to form the desired compound. Careful manipulation of reaction conditions is necessary to ensure high purity and yield of 2-Oxoarginine.

The procurement of 2-Oxoarginine for research or industrial use can be done through specialized chemical suppliers. These suppliers offer the compound in various quantities, typically in solid form. Transportation of 2-Oxoarginine is usually done using standard chemical shipping methods, following all regulations for the safe handling and transport of hazardous materials. It is essential to ensure proper packaging and labeling to prevent any accidents during transit.

Upon arrival, the received 2-Oxoarginine should be stored in a dry and cool environment to maintain its stability and integrity. Proper documentation regarding the compound’s handling instructions and safety data should be provided by the supplier and followed diligently. Before use, thorough risk assessments should be conducted to ensure safe handling and disposal practices are adhered to throughout the process.

⚠️ Safety Considerations

Safety considerations for 2-Oxoarginine include its potential as a hazardous substance if not handled properly. It is important to store 2-Oxoarginine in a cool, dry place away from direct sunlight, as exposure to heat and light can cause degradation of the compound. Additionally, proper labeling of containers containing 2-Oxoarginine is crucial to prevent accidental ingestion or contact with skin or eyes.

Pharmacologically, 2-Oxoarginine is known to inhibit nitric oxide synthesis by competing with L-arginine for nitric oxide synthase. This inhibition can have implications for cardiovascular health and regulate blood pressure. Studies have shown that 2-Oxoarginine can have anti-inflammatory effects by reducing nitric oxide production, potentially making it a target for therapeutic interventions in conditions related to excessive nitric oxide synthesis.

Hazard statements for 2-Oxoarginine include the potential for skin and eye irritation upon contact, as well as the risk of respiratory irritation if inhaled. It is important to take precautions such as wearing appropriate personal protective equipment, including gloves and goggles, when handling 2-Oxoarginine to reduce the risk of exposure. In case of contact with skin, eyes, or if inhaled, it is recommended to seek medical attention immediately.

Precautionary statements for 2-Oxoarginine include the need for proper ventilation in areas where the compound is stored or handled to prevent the build-up of potentially harmful vapors. It is also advisable to wash hands thoroughly after handling 2-Oxoarginine and to avoid eating, drinking, or smoking in areas where the compound is present. In the event of a spill, it is important to contain the spill and clean it up following proper hazardous material handling procedures.

🔬 Potential Research Directions

Research on 2-Oxoarginine has potential in various areas, such as studying its role in oxidative stress and inflammation. The compound’s ability to modulate nitric oxide production suggests possible therapeutic applications in cardiovascular diseases. Additionally, further investigations into its interactions with other cellular pathways may provide insights into its broader physiological significance.

Exploring the mechanisms behind 2-Oxoarginine’s impact on protein synthesis and metabolism could offer novel avenues in understanding cellular physiology. Its potential as a regulator of mitochondrial function and energy production warrants investigation into its effects on cellular bioenergetics. Furthermore, studies on its role in modulating cell signaling pathways may uncover new targets for drug development.

Investigating the pharmacokinetics and biodistribution of 2-Oxoarginine may provide valuable information for potential clinical use. Developing novel 2-Oxoarginine derivatives with improved bioavailability and specificity could enhance its therapeutic potential. Furthermore, examining its interactions with other drugs or compounds may offer insights into potential drug-drug interactions and synergies.

Another compound with a molecular structure similar to 2-Oxoarginine is 2-Oxoglutamine. This compound, also known as 2-Oxo-L-glutamine, is a derivative of the amino acid glutamine. It contains a ketone group at the second carbon, similar to 2-Oxoarginine, and is involved in various metabolic pathways in the body.

2-Oxoornithine is another closely related compound to 2-Oxoarginine. This compound is a derivative of the amino acid ornithine and contains a ketone group at the second carbon as well. Like 2-Oxoarginine, 2-Oxoornithine is important in various metabolic processes and plays a role in the urea cycle in the liver.

Lastly, 2-Oxocitrulline is a compound with a molecular structure similar to 2-Oxoarginine. This compound is a derivative of the amino acid citrulline and contains a ketone group at the second carbon, like 2-Oxoarginine. 2-Oxocitrulline is involved in the urea cycle and plays a role in the detoxification of ammonia in the body.

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