2′-Methylacetoacetanilide has relevance to everyday life due to its applications in the pharmaceutical industry. This compound is commonly used as a precursor for the synthesis of various pharmaceuticals, particularly those with analgesic and anti-inflammatory properties. As such, it plays a vital role in the development of medications that are crucial for the treatment of pain and inflammation in individuals worldwide. Additionally, 2′-Methylacetoacetanilide’s significance extends beyond healthcare, as it is also utilized in the production of dyes, pigments, and other chemical compounds. Its versatile properties make it an essential component in various commercial products that we encounter in our daily lives.
Table of Contents:
- 💡 Commercial Applications
- ⚗️ Chemical & Physical Properties
- 🏭 Production & Procurement
- ⚠️ Safety Considerations
- 🔬 Potential Research Directions
- 🧪 Related Compounds
💡 Commercial Applications
2′-Methylacetoacetanilide, also known as MAA, has various commercial and industrial applications. It is commonly used as a chemical intermediate in the synthesis of dyes, pharmaceuticals, and agrochemicals. Its high efficiency in promoting reactions makes it a valuable compound in the production of fine chemicals.
In the pharmaceutical industry, 2′-Methylacetoacetanilide is utilized in the synthesis of various drugs and medications. It serves as a key building block in the production of analgesics, anti-inflammatory drugs, and antipyretics. Its unique chemical structure and reactivity make it a versatile compound for drug development.
Furthermore, 2′-Methylacetoacetanilide finds applications in the manufacturing of specialty chemicals and polymers. Its ability to undergo various chemical transformations allows it to be incorporated into a wide range of industrial processes. This compound plays a crucial role in the creation of advanced materials used in electronics, coatings, and adhesives.
⚗️ Chemical & Physical Properties
2′-Methylacetoacetanilide appears as a white crystalline solid with a faint odor. It is not naturally found in common food items.
The molar mass of 2′-Methylacetoacetanilide is 201.24 g/mol, with a density of 1.177 g/cm3. Compared to common food items like sugar (molar mass: 342.3 g/mol, density: 1.59 g/cm3), 2′-Methylacetoacetanilide has a lower molar mass and density.
2′-Methylacetoacetanilide has a melting point of 140-142°C and a boiling point of 322-324°C. Compared to common food items like butter (melting point: 32-35°C, boiling point: 250°C) and water (melting point: 0°C, boiling point: 100°C), 2′-Methylacetoacetanilide has significantly higher melting and boiling points.
2′-Methylacetoacetanilide is sparingly soluble in water and exhibits low viscosity. Compared to common food items like salt (soluble in water) and honey (high viscosity), 2′-Methylacetoacetanilide has limited solubility and lower viscosity.
🏭 Production & Procurement
2′-Methylacetoacetanilide is typically produced through a multi-step organic synthesis process. The starting materials for this process usually include acetoacetanilide and methyl iodide, which react under specific conditions to form 2′-Methylacetoacetanilide as the final product. The reaction typically involves the addition of a base to facilitate the formation of the desired compound.
In order to procure 2′-Methylacetoacetanilide, one must typically purchase it from a chemical supplier that specializes in fine chemicals or pharmaceutical intermediates. The compound is typically available in the form of a powder or crystalline solid. Due to its sensitive nature, 2′-Methylacetoacetanilide must be handled and transported with care to prevent degradation or contamination. Suppliers often provide specific instructions for storage and handling to ensure the quality and integrity of the compound during transportation.
When procuring 2′-Methylacetoacetanilide, it is important to consider the purity and quality of the compound. High-quality suppliers will provide certificates of analysis (COA) and other documentation to validate the purity and identity of the product. Additionally, proper labeling and packaging are essential to ensure the safe and secure transportation of 2′-Methylacetoacetanilide. It is recommended to work with reputable suppliers who adhere to strict quality control standards to guarantee the reliability of the compound.
⚠️ Safety Considerations
Safety considerations for 2′-Methylacetoacetanilide are crucial due to its potential hazards. This compound should be handled with care in a well-ventilated area to avoid inhalation. It is important to wear appropriate personal protective equipment, such as gloves and goggles, when working with 2′-Methylacetoacetanilide to prevent skin contact and eye irritation.
Additionally, proper storage of 2′-Methylacetoacetanilide is essential to reduce the risk of accidents. This compound should be stored in a cool, dry place away from heat and sources of ignition. It is also important to keep 2′-Methylacetoacetanilide away from incompatible materials to prevent reactions or spills that could lead to harmful exposure.
Prolonged or repeated exposure to 2′-Methylacetoacetanilide may cause skin sensitization or other health effects. Therefore, it is recommended to limit exposure to this compound and seek medical attention if any adverse symptoms occur. Following these safety considerations when handling 2′-Methylacetoacetanilide is essential to minimize risks and ensure a safe working environment.
The hazard statements for 2′-Methylacetoacetanilide include “Causes skin irritation” and “May cause an allergic skin reaction.” These statements indicate the potential risks associated with skin contact with this compound and highlight the importance of wearing appropriate personal protective equipment to prevent irritation or sensitization. It is important to be aware of these hazards when working with 2′-Methylacetoacetanilide to minimize the risk of adverse effects on skin health.
Precautionary statements for 2′-Methylacetoacetanilide include “Avoid breathing dust/fume/gas/mist/vapors/spray” and “Wash hands and other exposed areas thoroughly after handling.” These statements emphasize the importance of proper ventilation and hygiene practices when working with this compound to reduce the risk of inhalation and skin exposure. Following these precautionary measures is essential to ensure the safe handling of 2′-Methylacetoacetanilide and minimize the potential health hazards associated with its use.
🔬 Potential Research Directions
Research on 2′-Methylacetoacetanilide has primarily focused on its potential applications as a pharmaceutical intermediate. This compound has shown promising properties in the synthesis of drugs due to its structure, which includes a combination of an acetoacetanilide and a methyl group.
One potential research direction could involve exploring the effectiveness of 2′-Methylacetoacetanilide in the development of new medication formulations. This could involve testing its compatibility with other active ingredients or evaluating its bioavailability and pharmacokinetic properties.
Another research avenue could involve investigating the potential biological activities of 2′-Methylacetoacetanilide. Studies could focus on its anti-inflammatory, antioxidant, or antimicrobial properties, which could offer valuable insights into its potential therapeutic applications in various disease conditions.
🧪 Related Compounds
One similar compound to 2′-Methylacetoacetanilide based upon molecular structure is Acetanilide. Acetanilide has a similar structure to 2′-Methylacetoacetanilide with the exception of the methyl group at the 2′ position. This compound is an organic compound commonly used as an aid to treat headaches and fever.
Another similar compound to 2′-Methylacetoacetanilide is N-Methylacetanilide. N-Methylacetanilide shares a similar structure with 2′-Methylacetoacetanilide but lacks the acetoacetyl group. This compound is often used in organic synthesis and as an intermediate in the production of other compounds.
A third compound similar to 2′-Methylacetoacetanilide is Acetylacetone. Acetylacetone is structurally related to 2′-Methylacetoacetanilide as it contains the acetoacetyl group with a carbonyl group on either side. This compound is commonly used as a ligand in coordination chemistry and as a precursor in the synthesis of other organic compounds.
