2-Methoxybenzoic acid, also known as o-Anisic acid, is a compound commonly used in the pharmaceutical industry as an intermediate in the production of various drugs. It also finds applications in the field of organic synthesis and as a precursor to fragrances and flavors in the food industry. Despite its significance in industrial processes, the average person may not encounter or directly interact with 2-Methoxybenzoic acid in their daily life.
Table of Contents:
- 💡 Commercial Applications
- ⚗️ Chemical & Physical Properties
- 🏭 Production & Procurement
- ⚠️ Safety Considerations
- 🔬 Potential Research Directions
- 🧪 Related Compounds
💡 Commercial Applications
2-Methoxybenzoic acid, also known as o-Anisic acid, has various commercial and industrial applications. It is commonly used as a fragrance ingredient in the cosmetic and perfume industry. It is also used as a chemical intermediate in the synthesis of pharmaceuticals, flavors, and other fine chemicals.
In the pharmaceutical industry, 2-Methoxybenzoic acid is utilized as a key intermediate in the production of various drugs and medications. It is particularly important in the synthesis of antibiotics, anti-inflammatory drugs, and antipyretic agents. Its versatile chemical properties make it a valuable component in the pharmaceutical manufacturing process.
Aside from its pharmaceutical and industrial applications, 2-Methoxybenzoic acid also finds use in organic synthesis and as a corrosion inhibitor. It has demonstrated effectiveness in inhibiting the corrosion of metal surfaces, making it a valuable additive in the production of rust-proof coatings. Additionally, its role in organic synthesis contributes to the creation of various specialty chemicals used in a wide range of industries.
⚗️ Chemical & Physical Properties
2-Methoxybenzoic acid is a white crystalline solid with a slight odor. It appears as fine crystals or powder and has a molecular formula of C8H8O3.
The molar mass of 2-Methoxybenzoic acid is 152.15 g/mol, with a density of 1.29 g/cm^3. Compared to common food items, such as sugar (molar mass of 342.30 g/mol) and olive oil (density of 0.92 g/cm^3), 2-Methoxybenzoic acid has a lower molar mass and higher density.
2-Methoxybenzoic acid has a melting point of 119-121°C and a boiling point of 275°C. In comparison to common food items like butter (melting point of 30-35°C) and water (boiling point of 100°C), 2-Methoxybenzoic acid has a higher melting and boiling point.
2-Methoxybenzoic acid is sparingly soluble in water and has a low viscosity. Compared to common food items like salt (high solubility in water) and honey (high viscosity), 2-Methoxybenzoic acid has limited solubility and low viscosity.
🏭 Production & Procurement
2-Methoxybenzoic acid, also known as o-anisic acid, is typically produced through the methylation of salicylic acid with dimethyl sulfate or methyl iodide under basic conditions. This reaction results in the formation of the desired product, which can then be isolated and purified through techniques such as recrystallization.
2-Methoxybenzoic acid can be procured from chemical suppliers or manufacturers who produce and distribute various specialty chemicals. It is often available in both powder and liquid form, with varying purities depending on the intended application. Upon procurement, the product can be transported in sealed containers to prevent contamination or degradation during transit.
Transportation of 2-Methoxybenzoic acid is typically conducted in accordance with regulations governing the shipment of hazardous chemicals to ensure safe handling and delivery. Common modes of transportation include road, rail, or air transport, depending on the distance and urgency of the shipment. Proper labeling and packaging are crucial to prevent accidental spills or leaks during transit.
⚠️ Safety Considerations
Safety considerations for 2-Methoxybenzoic acid include the potential for skin and eye irritation upon contact, as well as the possibility of respiratory irritation if inhaled. It is important to handle this compound with care, using appropriate personal protective equipment such as gloves, goggles, and a lab coat. Additionally, 2-Methoxybenzoic acid should be stored in a well-ventilated area away from incompatible substances to prevent any potential fire or explosion hazards.
Hazard statements for 2-Methoxybenzoic acid include “Causes skin irritation” and “Causes serious eye irritation.” These statements indicate the potential for skin and eye irritation upon contact with this compound. It is important to take precautions to minimize exposure and to seek medical attention if any adverse effects occur.
Precautionary statements for 2-Methoxybenzoic acid include “Wear protective gloves/protective clothing/eye protection/face protection” and “IF ON SKIN: Wash with plenty of soap and water.” These statements emphasize the importance of using appropriate personal protective equipment and taking prompt action in case of skin contact. It is crucial to follow these precautions to ensure safe handling of 2-Methoxybenzoic acid.
🔬 Potential Research Directions
Potential research directions for 2-Methoxybenzoic acid could include its use as a building block in the synthesis of various pharmaceuticals and agrochemicals.
Further studies may focus on the investigation of its antioxidant properties and potential applications in the food and cosmetics industries.
Exploration of the reactivity of 2-Methoxybenzoic acid in different chemical reactions and its role in the formation of coordination complexes could also be areas of interest for researchers in the field.
🧪 Related Compounds
One similar compound to 2-Methoxybenzoic acid is 3-Methoxybenzoic acid, which also contains a methoxy group (-OCH3) attached to the benzene ring at the para position. This compound differs from 2-Methoxybenzoic acid in the position of the methoxy group on the benzene ring.
Another similar compound is 4-Methoxybenzoic acid, in which the methoxy group is attached to the benzene ring at the meta position. This compound shares the methoxy group with 2-Methoxybenzoic acid but differs in its position on the benzene ring.
Additionally, 2-Ethoxybenzoic acid is a related compound with an ethoxy group (-OC2H5) attached to the benzene ring in lieu of a methoxy group. This compound has a similar structure to 2-Methoxybenzoic acid but with an ethoxy group instead of a methoxy group.
