2-Methoxy-N,N,beta-trimethyl-10H-phenothiazine-10-propylamine is a compound commonly known as methylene blue, is a medication with various medical uses. It is primarily used as a dye in medical imaging and as a treatment for methemoglobinemia, a rare blood disorder. Additionally, methylene blue has shown promise in treating conditions such as sepsis, Alzheimer’s disease, and depression, highlighting its potential importance in everyday life for individuals facing these health challenges.
Table of Contents:
- 💡 Commercial Applications
- ⚗️ Chemical & Physical Properties
- 🏭 Production & Procurement
- ⚠️ Safety Considerations
- 🔬 Potential Research Directions
- 🧪 Related Compounds
💡 Commercial Applications
2-Methoxy-N,N,beta-trimethyl-10H-phenothiazine-10-propylamine, also known as methylene blue, is commonly used as a dye in various commercial applications. It is utilized in the textile industry to dye fabrics and in the printing industry to color paper. Additionally, this compound is used in the food industry as a colorant for certain products.
In industrial applications, 2-Methoxy-N,N,beta-trimethyl-10H-phenothiazine-10-propylamine is employed as a redox indicator to detect electron transfer reactions. It is also used as a biological stain in laboratories for various applications, such as staining cells for microscopic analysis. Furthermore, this compound can be utilized in wastewater treatment processes to help remove harmful contaminants.
In the field of medicine, 2-Methoxy-N,N,beta-trimethyl-10H-phenothiazine-10-propylamine has various drug and medication applications. It is used as a medication to treat methemoglobinemia, a condition where the blood contains high levels of methemoglobin. Additionally, this compound has been studied for its potential therapeutic effects in treating Alzheimer’s disease and other neurodegenerative disorders. Overall, the pharmaceutical industry continues to explore the diverse medicinal properties of methylene blue.
⚗️ Chemical & Physical Properties
2-Methoxy-N,N,beta-trimethyl-10H-phenothiazine-10-propylamine appears as a white crystalline solid with a faint odor. This compound is highly sensitive to light and air, requiring proper handling and storage conditions to maintain its integrity.
With a molar mass of approximately 339.5 g/mol and a density of around 1.1 g/cm³, 2-Methoxy-N,N,beta-trimethyl-10H-phenothiazine-10-propylamine is significantly heavier and denser than common food items like water (molar mass: 18.015 g/mol, density: 1 g/cm³) and sugar (molar mass: 342.3 g/mol, density: 1.59 g/cm³).
The melting point of 2-Methoxy-N,N,beta-trimethyl-10H-phenothiazine-10-propylamine is approximately 80-85°C, while the boiling point ranges from 250-260°C. In comparison, common food items like butter (melting point: 32-35°C) and water (boiling point: 100°C) exhibit lower melting and boiling points.
2-Methoxy-N,N,beta-trimethyl-10H-phenothiazine-10-propylamine is sparingly soluble in water and exhibits low viscosity in solution. This differs from common food items like salt (high solubility in water) and honey (high viscosity), highlighting the unique chemical properties of this compound.
🏭 Production & Procurement
2-Methoxy-N,N,beta-trimethyl-10H-phenothiazine-10-propylamine is typically produced through a complex series of chemical reactions in a laboratory setting. The synthesis of this compound involves combining specific precursors and reagents in carefully controlled conditions to yield the desired end product.
Once 2-Methoxy-N,N,beta-trimethyl-10H-phenothiazine-10-propylamine has been successfully synthesized, it can be procured from chemical suppliers that specialize in providing rare and unique compounds. This compound is often shipped in sealed containers or vials to ensure its stability during transport. Special precautions may be necessary to comply with regulations governing the handling and transport of potentially hazardous chemicals.
It is essential to follow established safety protocols when handling and transporting 2-Methoxy-N,N,beta-trimethyl-10H-phenothiazine-10-propylamine due to its potential chemical reactivity and toxicity. Proper labeling and documentation should accompany the compound to ensure its safe and secure delivery to its intended destination. Additionally, the use of appropriate protective equipment and storage conditions is imperative to prevent accidents or exposure to this compound.
⚠️ Safety Considerations
Safety considerations for 2-Methoxy-N,N,beta-trimethyl-10H-phenothiazine-10-propylamine (also known as MPP+) must be carefully observed due to its potent neurotoxicity. This compound is known to be harmful if swallowed, inhaled, or in contact with skin. It may cause irritation to the respiratory system, skin, and eyes. Proper personal protective equipment, such as gloves, safety goggles, and a lab coat, should be worn when handling this substance. Adequate ventilation is essential to minimize exposure to airborne particles.
Hazard statements for 2-Methoxy-N,N,beta-trimethyl-10H-phenothiazine-10-propylamine include “Causes skin irritation,” “Causes serious eye irritation,” “Harmful if swallowed,” “May cause respiratory irritation,” and “Suspected of causing cancer.” These statements highlight the potential dangers associated with exposure to this chemical compound. It is important to handle and store this substance with caution to prevent any adverse health effects.
Precautionary statements for 2-Methoxy-N,N,beta-trimethyl-10H-phenothiazine-10-propylamine include “Wash hands thoroughly after handling,” “Do not eat, drink or smoke when using this product,” “Avoid release to the environment,” and “Wear protective gloves/protective clothing/eye protection/face protection.” These precautions are essential to minimize the risk of exposure to this toxic compound and to ensure the safety of individuals working with it. Proper storage and disposal methods should also be followed to prevent environmental contamination.
🔬 Potential Research Directions
One potential research direction for 2-Methoxy-N,N,beta-trimethyl-10H-phenothiazine-10-propylamine is the investigation of its pharmacological properties, specifically its potential as a therapeutic agent for certain psychiatric disorders such as schizophrenia or bipolar disorder. Studies could focus on its interaction with neurotransmitter systems and receptor sites to elucidate its mechanism of action.
Another avenue of research could involve exploring the synthesis and development of novel derivatives of 2-Methoxy-N,N,beta-trimethyl-10H-phenothiazine-10-propylamine with enhanced pharmacological profiles. By modifying the chemical structure of the compound, researchers may be able to optimize its efficacy, improve its bioavailability, or reduce potential side effects. This could lead to the discovery of more potent and selective compounds with improved therapeutic potential.
🧪 Related Compounds
One comparable compound to 2-Methoxy-N,N,beta-trimethyl-10H-phenothiazine-10-propylamine is 2-Ethoxy-N,N,beta-trimethyl-10H-phenothiazine-10-propylamine. This compound differs from the original one by replacing the methoxy group with an ethoxy group, resulting in a change in physical and chemical properties. The introduction of an ethoxy group may alter solubility, reactivity, or pharmacological effects.
Another similar compound is 2-Hydroxy-N,N,beta-trimethyl-10H-phenothiazine-10-propylamine. By incorporating a hydroxy group in place of the methoxy group, this compound assumes distinct characteristics while still sharing core structural similarities with the primary compound. The hydroxy group may confer different biological activities, metabolic fates, or binding interactions compared to the methoxy analog.
