2-Iodoanisole, a chemical compound used as a building block in organic synthesis, holds relevance in everyday life due to its applications in pharmaceuticals, agrochemicals, and material science. Specifically, it is utilized in the production of various drugs and as a precursor in the creation of fragrances and flavors. Its versatile nature and significance in these industries make it an important component in the development of products that impact consumers on a daily basis.
Table of Contents:
- 💡 Commercial Applications
- ⚗️ Chemical & Physical Properties
- 🏭 Production & Procurement
- ⚠️ Safety Considerations
- 🔬 Potential Research Directions
- 🧪 Related Compounds
💡 Commercial Applications
2-Iodoanisole, also known as o-iodoanisole, finds various commercial and industrial applications. It is commonly used as a building block in organic synthesis for the production of pharmaceuticals, agrochemicals, dyes, and other fine chemicals. Its reactivity with a range of functional groups makes it a versatile compound in the chemical industry.
In the realm of drug and medication applications, 2-Iodoanisole serves as a crucial intermediate in the synthesis of various biologically active compounds. It is utilized in the preparation of pharmaceutical ingredients and drug candidates due to its ability to undergo diverse chemical reactions. Its presence in the pharmaceutical industry underscores its importance as a valuable chemical building block.
Furthermore, 2-Iodoanisole plays a significant role in the development of novel drug formulations and therapies. Its unique chemical properties allow for the creation of specialized drug molecules with enhanced pharmacological activities. Research efforts continue to explore the full potential of 2-Iodoanisole in drug discovery and development, highlighting its promising prospects in the pharmaceutical sector.
⚗️ Chemical & Physical Properties
2-Iodoanisole is a colorless to pale yellow liquid with a faint aromatic odor. It is commonly used as an intermediate in the synthesis of organic compounds due to its reactivity.
The molar mass of 2-Iodoanisole is approximately 230.05 g/mol, with a density of around 1.71 g/cm³. In comparison to common food items, 2-Iodoanisole has a higher molar mass and density than substances like sugar or salt.
The melting point of 2-Iodoanisole is approximately -32°C, while the boiling point is around 227°C. Compared to common food items, 2-Iodoanisole has higher melting and boiling points than substances like butter or chocolate.
2-Iodoanisole is not soluble in water and has a low viscosity. In comparison to common food items, 2-Iodoanisole is less soluble in water and less viscous than substances like oil or honey.
🏭 Production & Procurement
2-Iodoanisole is typically produced through the iodination of anisole. This reaction involves reacting anisole with iodine in the presence of a strong oxidizing agent, such as sodium hypochlorite, in an organic solvent. The resulting product is then isolated and purified to obtain the desired 2-Iodoanisole compound.
In terms of procurement and transportation, 2-Iodoanisole can be obtained from chemical suppliers who specialize in providing specialty chemicals to researchers and manufacturers. Due to the compound’s potentially hazardous nature, it is important to follow proper safety protocols when handling and transporting 2-Iodoanisole. It is typically shipped in tightly sealed containers, often in specialized packaging designed to prevent leaks or spills during transit.
Upon arrival, the 2-Iodoanisole should be stored in a cool, dry place away from direct sunlight and sources of ignition. It is crucial to follow storage guidelines provided by the supplier to ensure the compound’s stability and integrity. When handling 2-Iodoanisole, appropriate personal protective equipment should be worn to prevent exposure to skin, eyes, and respiratory system. Proper disposal methods should also be followed to minimize environmental impact.
⚠️ Safety Considerations
Safety considerations for 2-Iodoanisole include its potential as a flammable liquid, with a flash point of 65 degrees Celsius, which means that it should be kept away from ignition sources and stored in a cool, well-ventilated area. Additionally, 2-Iodoanisole is a skin and eye irritant, so proper personal protective equipment, such as gloves and goggles, should be worn when handling this compound. Furthermore, exposure to 2-Iodoanisole should be minimized, as it may cause respiratory irritation and could be harmful if swallowed or inhaled.
The hazard statements for 2-Iodoanisole include: “Causes serious eye irritation,” “Causes skin irritation,” and “May cause respiratory irritation.” These statements indicate that contact with 2-Iodoanisole can result in harmful effects on the eyes, skin, and respiratory system. It is crucial to handle this compound with care and take appropriate safety precautions to prevent any adverse health effects.
Precautionary statements for 2-Iodoanisole include: “Wear protective gloves/protective clothing/eye protection/face protection,” “IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do,” and “IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.” These statements emphasize the importance of wearing proper protective equipment, taking immediate action in case of exposure, and seeking medical attention if necessary when dealing with 2-Iodoanisole. It is crucial to follow these precautions to ensure the safe handling of this compound.
🔬 Potential Research Directions
One potential research direction for 2-Iodoanisole could involve investigating its reactivity towards various nucleophiles in order to synthesize new organic compounds. This could lead to the development of novel pharmaceuticals or materials with useful properties.
Another potential research direction for 2-Iodoanisole could focus on exploring its potential as a reagent in cross-coupling reactions to form C-C and C-heteroatom bonds. Such studies could provide valuable insights into its utility as a building block for the synthesis of complex organic molecules with diverse applications in chemical industry and academia.
🧪 Related Compounds
One similar compound to 2-Iodoanisole based upon molecular structure is 2-Bromoanisole. In this compound, the iodine atom in 2-Iodoanisole is replaced with a bromine atom. This substitution results in a similar structure with a different halogen atom attached to the aromatic ring.
Another similar compound to 2-Iodoanisole is 2-Chloroanisole. In this compound, the iodine atom is replaced with a chlorine atom, resulting in a compound with a similar structure and different halogen substitution. This substitution affects the reactivity and properties of the compound.
A further similar compound to 2-Iodoanisole is Anisole. In this compound, the iodine atom is replaced with a hydrogen atom, resulting in a compound with a similar basic structure but lacking a halogen substituent. This variation in structure affects the reactivity and properties of the compound compared to 2-Iodoanisole.
