2-Hydroxyquinoxaline, a compound commonly used in the pharmaceutical industry, is relevant to everyday life due to its potential therapeutic applications. This compound has been shown to possess various pharmacological properties, including antioxidant, antimicrobial, and anti-inflammatory effects. These properties make 2-Hydroxyquinoxaline a promising candidate for the development of new drugs to combat a range of medical conditions. From treating infections to reducing inflammation, the potential benefits of 2-Hydroxyquinoxaline highlight its importance in advancing healthcare and improving quality of life for individuals.
Table of Contents:
- 💡 Commercial Applications
- ⚗️ Chemical & Physical Properties
- 🏭 Production & Procurement
- ⚠️ Safety Considerations
- 🔬 Potential Research Directions
- 🧪 Related Compounds
💡 Commercial Applications
2-Hydroxyquinoxaline, also known as 2-Quinoxalineol, has various commercial and industrial applications. It is utilized as an intermediate in the synthesis of pharmaceuticals, pesticides, and dyes. Additionally, this compound is employed in the production of rubber accelerators and corrosion inhibitors due to its ability to form coordination complexes with transition metal ions.
In the realm of drug and medication applications, 2-Hydroxyquinoxaline plays a crucial role as a building block in the synthesis of several biologically active compounds. It serves as a key precursor in the creation of antimalarial agents, anti-cancer drugs, and antimicrobial agents. Its versatile chemical structure allows for modifications that can enhance the biological activity and pharmacological properties of these therapeutic agents.
⚗️ Chemical & Physical Properties
2-Hydroxyquinoxaline is a white crystalline solid with a faint characteristic odor. It is sparingly soluble in water and organic solvents.
The molar mass of 2-Hydroxyquinoxaline is 146.12 g/mol, and its density is approximately 1.41 g/cm³. Compared to common food items such as sugar (180.16 g/mol) and salt (58.44 g/mol), 2-Hydroxyquinoxaline has a lower molar mass.
The melting point of 2-Hydroxyquinoxaline is around 146-148°C, and its boiling point is approximately 340°C. In comparison, common food items like butter (melting point around 32-35°C) and water (boiling point at 100°C) have significantly lower melting and boiling points.
2-Hydroxyquinoxaline is slightly soluble in water and has a low viscosity. This is in contrast to common food items like sugar, which is highly soluble in water, and honey, which has a higher viscosity.
🏭 Production & Procurement
2-Hydroxyquinoxaline is typically produced through a multi-step synthesis process in a laboratory setting. The starting materials for this synthesis are quinoxaline and a suitable oxidizing agent, such as hydrogen peroxide or potassium permanganate. The oxidation of quinoxaline yields 2-Hydroxyquinoxaline as the final product.
2-Hydroxyquinoxaline can be procured commercially from chemical suppliers that specialize in providing fine chemicals and research materials. The compound is available in various purities and quantities to accommodate the specific needs of researchers and manufacturers. Once procured, 2-Hydroxyquinoxaline can be transported in sealed containers to prevent contamination or degradation during transit.
For transportation, 2-Hydroxyquinoxaline is typically packaged in standard chemical containers that meet regulatory requirements for handling and transport. The compound is labeled with appropriate hazard information and safety precautions to ensure proper handling by individuals involved in its transportation. Specialized carriers may be used for transporting 2-Hydroxyquinoxaline to ensure compliance with regulations governing the transportation of hazardous materials.
⚠️ Safety Considerations
Safety considerations for 2-Hydroxyquinoxaline are paramount due to its potential hazards. This compound poses a risk of irritation to the skin, eyes, and respiratory system upon exposure. It is important to handle 2-Hydroxyquinoxaline with caution, ensuring proper ventilation and personal protective equipment are utilized to minimize the risk of adverse effects.
Furthermore, it is crucial to store 2-Hydroxyquinoxaline in a secure location, away from incompatible substances and sources of ignition. Proper labeling of containers containing this compound is essential to prevent accidental exposure and potential harm. In case of spillage or accidental release, appropriate clean-up procedures should be followed to prevent environmental contamination and harm to individuals.
In summary, hazard statements for 2-Hydroxyquinoxaline include the potential for skin, eye, and respiratory irritation upon exposure. Additionally, this compound may be harmful if swallowed or inhaled. It is important to handle 2-Hydroxyquinoxaline with care and follow proper safety protocols to minimize the risk of adverse effects.
Precautionary statements for 2-Hydroxyquinoxaline emphasize the importance of wearing appropriate personal protective equipment, such as gloves, goggles, and a respirator, when handling this compound. It is also recommended to work with 2-Hydroxyquinoxaline in a well-ventilated area to minimize exposure to fumes or vapors. Avoid contact with skin, eyes, and clothing, and wash hands thoroughly after handling to prevent potential irritation or harm. Additionally, store 2-Hydroxyquinoxaline in a cool, dry, well-ventilated area away from heat and sources of ignition. In case of accidental exposure or spillage, follow appropriate clean-up procedures and dispose of waste material in accordance with local regulations.
🔬 Potential Research Directions
Research on 2-Hydroxyquinoxaline has the potential to explore its pharmacological properties, including its antioxidant and anti-inflammatory effects. Studies may investigate its possible applications in drug development for treating various diseases.
Furthermore, research could focus on the synthesis and modification of 2-Hydroxyquinoxaline derivatives to enhance their biological activities. This may lead to the discovery of new compounds with improved efficacy and reduced side effects for use in pharmaceuticals.
Additionally, studies may investigate the mechanisms of action of 2-Hydroxyquinoxaline and its derivatives at the molecular level. Understanding the interactions of these compounds with cellular targets could provide valuable insights for designing more potent and selective drugs in the future.
🧪 Related Compounds
2-Hydroxyquinoxaline, with a molecular formula of C9H6N2O, belongs to a class of compounds known as quinoxalines. These compounds contain a benzene ring fused to a pyrazine ring. 2-Hydroxyquinoxaline specifically contains a hydroxy group on the benzene ring, giving it unique properties compared to other quinoxalines.
One similar compound to 2-Hydroxyquinoxaline is 2-Methylquinoxaline, which has a methyl group attached to the benzene ring in place of the hydroxy group. This substitution alters the chemical properties of the compound while still maintaining the basic structural framework of quinoxalines. 2-Methylquinoxaline can be used in a variety of organic synthesis reactions due to its close resemblance to 2-Hydroxyquinoxaline.
Another related compound is 2,3-Dihydroxyquinoxaline, which contains two hydroxy groups on the benzene ring of the quinoxaline structure. This compound exhibits different solubility and reactivity compared to 2-Hydroxyquinoxaline due to the presence of an additional hydroxy group. 2,3-Dihydroxyquinoxaline can be used in medicinal chemistry research for its unique properties in drug design and development.
