2-Hydroxycyclohexan-1-one, also known as 2-Hydroxycyclohexanone, is a chemical compound with potential applications in various industries, including pharmaceuticals, cosmetics, and flavors. It can be used as a building block in the synthesis of organic compounds, potentially leading to the development of new drugs, personal care products, and food additives. Its unique molecular structure and properties make it a valuable component in the research and development of innovative products that impact everyday life.
Table of Contents:
- 💡 Commercial Applications
- ⚗️ Chemical & Physical Properties
- 🏭 Production & Procurement
- ⚠️ Safety Considerations
- 🔬 Potential Research Directions
- 🧪 Related Compounds
💡 Commercial Applications
2-Hydroxycyclohexan-1-one, also known as 2-Hydroxy-1-cyclohexanone, has a variety of commercial and industrial applications. This compound is commonly used as a fragrance and flavoring agent in the cosmetic and food industries due to its pleasant odor and taste. Additionally, 2-Hydroxycyclohexan-1-one is utilized in the production of plasticizers and polymer resins, enhancing flexibility and durability in plastic products.
In terms of drug and medication applications, 2-Hydroxycyclohexan-1-one plays a crucial role in the synthesis of pharmaceutical compounds. This compound serves as a building block in the creation of various drugs, such as antiviral and antifungal medications. Furthermore, 2-Hydroxycyclohexan-1-one is used in the development of medical diagnostics and research chemicals, contributing to advancements in the healthcare industry.
⚗️ Chemical & Physical Properties
2-Hydroxycyclohexan-1-one, a cyclic ketone compound, appears as a colorless liquid with a slightly pungent odor. It is often used in the synthesis of pharmaceuticals and fragrances due to its unique chemical properties.
With a molar mass of approximately 128.17 g/mol and a density of 1.08 g/cm³, 2-Hydroxycyclohexan-1-one falls within the range of common household items such as acetone (molar mass: 58.08 g/mol, density: 0.79 g/cm³) and ethyl acetate (molar mass: 88.11 g/mol, density: 0.90 g/cm³).
The melting point of 2-Hydroxycyclohexan-1-one is around -5°C, while its boiling point is approximately 168°C. These properties place it in the same range as common household items like water (melting point: 0°C, boiling point: 100°C) and ethanol (melting point: -114.1°C, boiling point: 78.37°C).
2-Hydroxycyclohexan-1-one exhibits limited solubility in water, as it forms a cloudy solution when mixed. Its viscosity is relatively low compared to common household items such as sugar (soluble in water, high viscosity) and salt (soluble in water, low viscosity).
🏭 Production & Procurement
Production of 2-Hydroxycyclohexan-1-one involves the oxidation of cyclohexanone using suitable oxidizing agents such as hydrogen peroxide or chromic acid. This process typically occurs under reflux conditions to promote the oxidation reaction. The resulting 2-Hydroxycyclohexan-1-one can then be isolated and purified through techniques such as distillation or crystallization.
2-Hydroxycyclohexan-1-one can be procured commercially from chemical suppliers that specialize in fine chemicals and specialty intermediates. The compound is typically available in varying quantities ranging from grams to kilograms. Upon procurement, the compound is usually packaged in suitable containers to ensure its safe transportation.
For transportation purposes, 2-Hydroxycyclohexan-1-one is commonly shipped in sealed containers to prevent leakage and contamination. The compound may be classified as hazardous material due to its chemical properties, requiring adherence to transportation regulations for hazardous substances. Proper labeling and documentation are essential for ensuring safe and compliant transportation of 2-Hydroxycyclohexan-1-one.
⚠️ Safety Considerations
Safety considerations for handling 2-Hydroxycyclohexan-1-one include wearing appropriate personal protective equipment such as gloves, goggles, and a lab coat to prevent skin contact and eye irritation. It is important to work with this chemical in a well-ventilated area to avoid inhaling vapors, and to handle it with caution to prevent accidental spills or exposure. Additionally, proper disposal methods should be followed to minimize environmental impact.
The pharmacology of 2-Hydroxycyclohexan-1-one involves its ability to act as a precursor in various organic synthesis reactions. This compound is commonly used in the pharmaceutical industry for the production of certain medications and as a key intermediate in chemical synthesis. Its pharmacological properties stem from its ability to react with other compounds and form new chemical structures with distinct biological activity.
Hazard statements for 2-Hydroxycyclohexan-1-one include “Causes skin irritation” and “Causes serious eye irritation.” These statements indicate the potential risks associated with exposure to this compound, emphasizing the importance of wearing protective equipment and practicing safe handling procedures. It is essential to be aware of these hazards and take necessary precautions to minimize the risk of harm to oneself and others.
Precautionary statements for 2-Hydroxycyclohexan-1-one include “Wear protective gloves/eye protection” and “Avoid breathing dust/fume/gas/mist/vapors/spray.” These statements serve as guidelines for safely working with this chemical, highlighting the importance of using proper personal protective equipment and working in a well-ventilated area. Following these precautions can help reduce the risk of exposure and ensure a safe working environment when handling 2-Hydroxycyclohexan-1-one.
🔬 Potential Research Directions
One potential research direction for 2-Hydroxycyclohexan-1-one could focus on its biological activity. Investigating its potential as a pharmaceutical compound for medicinal use, such as in drug development or as a therapeutic agent, could provide valuable insight into its pharmacological properties.
Another avenue for research on 2-Hydroxycyclohexan-1-one is its chemical reactivity and potential applications in organic synthesis. Exploring its reactivity towards different functional groups and its ability to participate in various chemical transformations could lead to the development of new synthetic methodologies or the production of novel compounds with specific properties.
🧪 Related Compounds
One similar compound to 2-Hydroxycyclohexan-1-one based upon molecular structure is 2-Hydroxycyclopentanone. This compound also contains a hydroxyl group attached to a cyclic carbon chain, but in this case, the carbon chain is a five-membered ring rather than a six-membered ring. The presence of the hydroxyl group in both compounds confers similar reactivity and chemical properties.
Another similar compound to 2-Hydroxycyclohexan-1-one is 2-Hydroxycycloheptanone. Like 2-Hydroxycyclohexan-1-one, this compound features a hydroxyl group attached to a cyclic carbon chain. However, in this case, the carbon chain forms a seven-membered ring. The presence of the hydroxyl group in both compounds allows for similar types of chemical reactions to occur, albeit with potential differences in reactivity due to the ring size.
Additionally, a related compound to 2-Hydroxycyclohexan-1-one is 3-Hydroxycyclohexanone. In this compound, the hydroxyl group is attached to a different carbon atom within the cyclohexanone ring compared to 2-Hydroxycyclohexan-1-one. This subtle structural difference can lead to variations in reactivity and chemical behavior between the two compounds, despite their overall similarities in molecular structure.