2-Hydroxy-3-(phosphonooxy)propyl octadec-9-enoate is a compound commonly used in personal care products such as lotions and cosmetics. This ingredient helps to moisturize and condition the skin, making it a popular choice for consumers looking to improve the health and appearance of their skin. Its relevance to everyday life lies in its ability to enhance the effectiveness of skincare products, providing users with a solution to common skin issues such as dryness and inflammation.
Table of Contents:
- 💡 Commercial Applications
- ⚗️ Chemical & Physical Properties
- 🏭 Production & Procurement
- ⚠️ Safety Considerations
- 🔬 Potential Research Directions
- 🧪 Related Compounds
💡 Commercial Applications
2-Hydroxy-3-(phosphonooxy)propyl octadec-9-enoate, also known as phosphatidylcholine, is primarily used in commercial and industrial applications for its emulsifying and dispersing properties. It is commonly used in cosmetics, pharmaceuticals, and food products as an emulsifier to stabilize and enhance the texture of various formulations.
In the pharmaceutical industry, 2-Hydroxy-3-(phosphonooxy)propyl octadec-9-enoate is often used in the formulation of lipid-based drug delivery systems. These systems can improve the bioavailability and efficacy of poorly water-soluble drugs by increasing their solubility and facilitating their absorption in the body. Additionally, phosphatidylcholine is used as an excipient in drug formulations to improve drug stability and delivery.
In terms of medication applications, phosphatidylcholine is sometimes included in dietary supplements and health products due to its potential health benefits. It is thought to support liver function, aid in digestion, and improve overall cell membrane health. However, the evidence supporting these claims is not definitive, and more research is needed to fully understand the potential therapeutic effects of 2-Hydroxy-3-(phosphonooxy)propyl octadec-9-enoate.
⚗️ Chemical & Physical Properties
2-Hydroxy-3-(phosphonooxy)propyl octadec-9-enoate appears as a white crystalline solid with no distinct odor. Its physical appearance is similar to common table salt or sugar.
The molar mass of 2-Hydroxy-3-(phosphonooxy)propyl octadec-9-enoate is approximately 510 g/mol, while its density is around 1.0 g/cm3. Compared to common food items like sucrose (342 g/mol) and olive oil (0.92 g/cm3), this compound has a higher molar mass and similar density.
The melting point of 2-Hydroxy-3-(phosphonooxy)propyl octadec-9-enoate is approximately 85-90°C, while its boiling point is around 300-310°C. In comparison, common food items like butter (melting point around 32-35°C) and water (boiling point at 100°C) have lower melting and boiling points.
2-Hydroxy-3-(phosphonooxy)propyl octadec-9-enoate is sparingly soluble in water and exhibits high viscosity. This is in contrast to common food items like sugar and salt, which are highly soluble in water and have low viscosity.
🏭 Production & Procurement
2-Hydroxy-3-(phosphonooxy)propyl octadec-9-enoate is typically produced through a multi-step chemical synthesis process. This process involves the reaction of octadec-9-enoic acid with phosphorous trichloride to form the corresponding acid chloride, followed by the addition of hydroxyethylidenediphosphonic acid to produce the desired product.
The production of 2-Hydroxy-3-(phosphonooxy)propyl octadec-9-enoate requires precise control of reaction conditions, including temperature, pressure, and reagent concentrations. Additionally, purification steps, such as column chromatography or recrystallization, may be necessary to isolate the final product in high purity.
Once produced, 2-Hydroxy-3-(phosphonooxy)propyl octadec-9-enoate can be procured from chemical suppliers specializing in fine chemicals and intermediates. The compound is typically supplied as a solid or liquid, depending on the specific formulation and intended use. Transportation of 2-Hydroxy-3-(phosphonooxy)propyl octadec-9-enoate may be carried out in sealed containers under controlled conditions to prevent degradation or contamination.
⚠️ Safety Considerations
Safety considerations for 2-Hydroxy-3-(phosphonooxy)propyl octadec-9-enoate are paramount due to its potential hazards. When handling this compound, it is important to wear appropriate personal protective equipment, such as gloves, goggles, and a lab coat, to prevent skin contact and inhalation of fumes. Additionally, this chemical should be stored in a cool, dry place away from incompatible substances to avoid any potential reactions or accidents.
The hazard statements for 2-Hydroxy-3-(phosphonooxy)propyl octadec-9-enoate include phrases such as “Causes skin irritation,” “Causes serious eye irritation,” and “May cause respiratory irritation.” These statements indicate the potential risks associated with exposure to this compound, highlighting the importance of taking necessary precautions to prevent any adverse effects on human health or the environment.
Precautionary statements for 2-Hydroxy-3-(phosphonooxy)propyl octadec-9-enoate involve recommendations for safe handling and storage of the chemical. It is advised to wash hands thoroughly after handling, avoid breathing dust/fume/gas/mist/vapors/spray, and use only outdoors or in a well-ventilated area. In case of fire, it is crucial to use appropriate firefighting measures, such as foam, CO2, dry powder, or water spray, to extinguish the flames and prevent further spread of the chemical.
🔬 Potential Research Directions
One potential research direction for 2-Hydroxy-3-(phosphonooxy)propyl octadec-9-enoate is the investigation of its biological activities, specifically its potential as an anti-inflammatory agent or its role in lipid metabolism.
Furthermore, research could focus on the development of synthetic methodologies or optimization of existing methods for the production of 2-Hydroxy-3-(phosphonooxy)propyl octadec-9-enoate, aiming to improve yield, purity, and cost-effectiveness.
Another possible research direction is the exploration of 2-Hydroxy-3-(phosphonooxy)propyl octadec-9-enoate’s potential applications in the field of cosmetics or pharmaceuticals, such as its use as an emollient, surfactant, or drug delivery system.
🧪 Related Compounds
One similar compound to 2-Hydroxy-3-(phosphonooxy)propyl octadec-9-enoate is 2-Hydroxy-3-(phosphonooxy)propyl dodec-9-enoate. This compound has the same hydroxy and phosphonooxy functional groups attached to a propyl chain, but with a shorter dodecyl chain compared to the octadecyl chain in the original compound.
Another analogous compound is 2-Hydroxy-3-(phosphonooxy)propyl hexadec-9-enoate. Similar to the previous compound, this variant features the hydroxy and phosphonooxy groups linked to a propyl chain, but with a hexadecyl chain instead of an octadecyl chain. This difference in chain length alters the physical and chemical properties of the compound.
A third comparable compound is 2-Hydroxy-3-(phosphonooxy)propyl tetradec-9-enoate. This compound bears resemblance to the original compound with its hydroxy and phosphonooxy groups connected to a propyl chain, but with a tetradecyl chain instead of an octadecyl chain. The change in alkyl chain length impacts the compound’s solubility, stability, and biological activity.
