2-Fluoropyridine is a chemical compound that has relevance in everyday life due to its utilization in the pharmaceutical industry. This compound serves as a building block in the synthesis of various drugs and pharmaceutical products. Its role in drug development and research highlights its importance in the medical field and underscores its impact on human health and well-being. The significance of 2-Fluoropyridine lies in its contribution to the advancement of healthcare through the creation of novel medications and treatments for a wide range of ailments.
Table of Contents:
- 💡 Commercial Applications
- ⚗️ Chemical & Physical Properties
- 🏭 Production & Procurement
- ⚠️ Safety Considerations
- 🔬 Potential Research Directions
- 🧪 Related Compounds
💡 Commercial Applications
2-Fluoropyridine, a chemical compound with the molecular formula C5H4FN, has various commercial and industrial applications. It is commonly used as an intermediate in the manufacturing of pharmaceuticals, agrochemicals, and other specialty chemicals. This compound is also utilized in the production of dyes, flavorings, and fragrances due to its unique chemical properties.
In the realm of drug and medication applications, 2-Fluoropyridine plays a significant role as a building block in the synthesis of various pharmaceuticals. It is often used in the development of antiviral drugs, anti-inflammatory medications, and anti-cancer treatments. The presence of fluorine in the compound enhances its bioavailability and pharmacokinetic properties, making it a valuable ingredient in the pharmaceutical industry.
Beyond its pharmaceutical applications, 2-Fluoropyridine is also employed in the synthesis of crop protection agents and insecticides. Its versatile chemical structure allows for the creation of potent pesticides that target specific pests while minimizing harm to the environment. Additionally, this compound is used in the production of specialty polymers and coatings, contributing to advancements in materials science and industrial processes.
⚗️ Chemical & Physical Properties
2-Fluoropyridine is a colorless liquid with a pungent odor. It is a member of the pyridine family of compounds, which are commonly used in organic synthesis.
The molar mass of 2-Fluoropyridine is approximately 110.1 g/mol, and its density is around 1.11 g/cm³. In comparison, common food items such as sugar and salt have molar masses in the range of 342.3 g/mol and 58.4 g/mol, respectively, and densities of approximately 1.59 g/cm³ and 2.17 g/cm³, respectively.
The melting point of 2-Fluoropyridine is -35°C, while its boiling point is 117°C. In contrast, common food items like butter have melting points around 32°C and boiling points around 177°C.
2-Fluoropyridine is sparingly soluble in water and has a relatively low viscosity. This is in contrast to common food items such as sugar, which are highly soluble in water, and honey, which has a high viscosity.
🏭 Production & Procurement
2-Fluoropyridine is commonly produced through a process known as fluorination, in which a fluorine atom is introduced into the pyridine molecule. This can be achieved through various methods, including direct fluorination using elemental fluorine or indirect fluorination using fluorinating agents such as hydrogen fluoride.
In order to procure 2-Fluoropyridine, one can source it from chemical suppliers and manufacturers who produce the compound for research and industrial applications. The compound can be purchased in bulk quantities or smaller amounts depending on the needs of the buyer. It is important to ensure proper storage and transportation conditions to maintain the integrity of the compound.
Transportation of 2-Fluoropyridine typically involves the use of specialized containers and packaging to prevent accidental spills or leaks during transit. The compound is often classified as a hazardous material due to its chemical properties, so it is essential to comply with regulations and guidelines for handling and transportation. Proper labeling and documentation are also necessary for the safe and legal transport of 2-Fluoropyridine.
⚠️ Safety Considerations
Safety considerations for 2-Fluoropyridine include the potential for skin and eye irritation upon contact. It is important to wear appropriate personal protective equipment, such as gloves and safety glasses, when handling this substance. Additionally, 2-Fluoropyridine should be stored in a cool, dry, well-ventilated area away from incompatible materials to prevent the risk of fire or chemical reaction.
Hazard statements for 2-Fluoropyridine include “Causes skin irritation” and “Causes serious eye irritation.” These statements indicate the potential health hazards associated with exposure to this substance. It is important to take necessary precautions to minimize the risk of skin and eye irritation when working with 2-Fluoropyridine.
Precautionary statements for 2-Fluoropyridine include “Avoid breathing dust/fume/gas/mist/vapors/spray” and “Wash hands thoroughly after handling.” These statements emphasize the importance of practicing safe handling procedures to minimize the risk of exposure. It is recommended to work with 2-Fluoropyridine in a well-ventilated area and to take appropriate measures to prevent skin contact.
🔬 Potential Research Directions
One potential research direction for 2-Fluoropyridine is its medicinal applications. Given its structural similarity to other fluoropyridine derivatives that have shown promising pharmacological properties, further investigation into the biological activities of 2-Fluoropyridine could reveal new therapeutic uses in drug development.
Another avenue of research for 2-Fluoropyridine could focus on its potential as a building block in organic synthesis. The incorporation of fluorine atoms into organic molecules can lead to compounds with unique reactivity and physical properties, making 2-Fluoropyridine a valuable tool for the construction of complex molecular frameworks.
Additionally, the study of the reactivity and stereochemistry of 2-Fluoropyridine in various chemical reactions could provide insights into the mechanism of fluorination processes and the behavior of fluorinated heterocycles. Understanding these fundamental aspects of 2-Fluoropyridine could contribute to the development of more efficient synthetic methodologies and facilitate the design of novel fluorinated compounds.
🧪 Related Compounds
One similar compound to 2-Fluoropyridine is 2-Chloropyridine, which has a molecular structure that is analogous to 2-Fluoropyridine but with a chlorine atom instead of a fluorine atom attached to the pyridine ring. This substitution results in different chemical properties and potential reactivity compared to 2-Fluoropyridine. 2-Chloropyridine is commonly used in organic synthesis and pharmaceutical research due to its unique properties.
Another related compound is 2-Bromopyridine, which shares a similar molecular structure with 2-Fluoropyridine, but with a bromine atom in place of the fluorine atom. This substitution impacts the compound’s physical and chemical properties, making 2-Bromopyridine a versatile building block in organic synthesis. Like 2-Fluoropyridine, 2-Bromopyridine is commonly employed in pharmaceutical research and agrochemical development due to its reactivity and stability.
A further analogous compound is 2-Iodopyridine, which bears resemblance to 2-Fluoropyridine in terms of molecular structure but incorporates an iodine atom in place of the fluorine atom. This substitution results in distinct chemical behavior and reactivity for 2-Iodopyridine compared to 2-Fluoropyridine. 2-Iodopyridine is used in various chemical reactions, particularly in cross-coupling reactions in organic synthesis, due to its unique properties and reactivity.
