2-Fluorobenzotrifluoride is a chemical compound that is used in various industrial applications, including as a building block in the production of pharmaceuticals, agrochemicals, and specialty chemicals. Its relevance to everyday life lies in its role in the manufacturing of products that we rely on daily, such as medications, pesticides, and other products that enhance our quality of life. Despite being a niche chemical, 2-Fluorobenzotrifluoride plays a crucial role in the modern economy and contributes to the advancements in various sectors that impact everyday life.
Table of Contents:
- 💡 Commercial Applications
- ⚗️ Chemical & Physical Properties
- 🏭 Production & Procurement
- ⚠️ Safety Considerations
- 🔬 Potential Research Directions
- 🧪 Related Compounds
💡 Commercial Applications
2-Fluorobenzotrifluoride, also known as 1,2-Difluoro-3-(trifluoromethyl)benzene, has various commercial and industrial applications. It is primarily utilized as an intermediate in the synthesis of agrochemicals, pharmaceuticals, and other organic compounds. Its unique chemical properties make it useful in the production of specialty polymers and coatings.
In terms of drug and medication applications, 2-Fluorobenzotrifluoride is not commonly used in the pharmaceutical industry. However, it can be employed as a building block for the synthesis of novel drug candidates. Its trifluoromethyl group can impart desirable pharmacokinetic properties to compounds, making it potentially valuable in drug discovery programs. Further research is needed to explore its full potential in medicinal chemistry.
⚗️ Chemical & Physical Properties
2-Fluorobenzotrifluoride is a colorless liquid with a faint odor. It is sparingly soluble in water and has a noticeable viscosity.
The molar mass of 2-Fluorobenzotrifluoride is approximately 180.1 g/mol, with a density of around 1.4 g/cm3. This places it in between common food items in terms of molar mass and density.
2-Fluorobenzotrifluoride has a melting point of -30°C and a boiling point of 138°C. These values are higher compared to common food items, which typically have lower melting and boiling points.
In terms of solubility in water, 2-Fluorobenzotrifluoride is not highly soluble, but it does exhibit a higher viscosity. This differs from common food items, which are usually more soluble in water and have lower viscosity levels.
🏭 Production & Procurement
2-Fluorobenzotrifluoride, a key intermediate in the synthesis of pharmaceuticals and agrochemicals, is primarily produced through a fluorination reaction involving benzotrifluoride and a fluorinating agent such as hydrogen fluoride. This reaction typically takes place under controlled conditions, including specific temperature and pressure requirements, to ensure high yields of the desired product.
The procurement of 2-Fluorobenzotrifluoride typically involves sourcing the compound from chemical suppliers or manufacturers who specialize in fluorinated compounds. Due to its specialized nature, 2-Fluorobenzotrifluoride may not be readily available from general chemical suppliers, requiring buyers to locate suppliers with expertise in fluorine chemistry. Once procured, the compound can be safely transported in sealed containers to prevent exposure to moisture or other reactive substances.
Transportation of 2-Fluorobenzotrifluoride is typically conducted in accordance with regulations governing the transport of hazardous or reactive chemicals. This may involve using specialized containers or packaging materials to ensure the compound’s stability during transit. Additionally, proper labeling and documentation are required to comply with international shipping regulations and ensure the safe handling of 2-Fluorobenzotrifluoride throughout the transportation process.
⚠️ Safety Considerations
Safety considerations for 2-Fluorobenzotrifluoride involve handling the compound with caution due to its hazardous properties. It is important to wear appropriate personal protective equipment, such as gloves, goggles, and a lab coat, when working with 2-Fluorobenzotrifluoride to prevent skin contact, eye irritation, and inhalation of vapors. The compound should only be used in a well-ventilated area to minimize exposure and the risk of respiratory irritation.
In addition, it is essential to store 2-Fluorobenzotrifluoride in a cool, dry, well-ventilated place away from sources of heat or ignition to prevent potential fire or explosion hazards. The compound should be kept away from incompatible materials, such as strong oxidizing agents, to avoid reactions that could lead to dangerous situations. Proper labeling and handling procedures should be followed when transporting or disposing of 2-Fluorobenzotrifluoride to prevent any accidental spills or environmental contamination.
Hazard statements for 2-Fluorobenzotrifluoride include “Causes skin irritation,” “Causes serious eye irritation,” “Harmful if swallowed,” and “May cause respiratory irritation.” These statements indicate the potential health hazards associated with exposure to 2-Fluorobenzotrifluoride and highlight the importance of following safety protocols to minimize risks. It is crucial to take necessary precautions to avoid skin and eye contact, inhalation of vapors, and ingestion of the compound to prevent adverse health effects.
Precautionary statements for 2-Fluorobenzotrifluoride include “Wear protective gloves/eye protection/face protection,” “IF ON SKIN: Wash with plenty of water,” “IF IN EYES: Rinse cautiously with water for several minutes,” and “IF SWALLOWED: Call a POISON CENTER/doctor.” These statements emphasize the importance of using appropriate personal protective equipment, such as gloves and goggles, to prevent skin and eye contact. In the event of exposure, prompt action should be taken to rinse affected areas with water and seek medical attention if necessary. It is essential to follow these precautionary measures to ensure safe handling and minimize the risks associated with 2-Fluorobenzotrifluoride.
🔬 Potential Research Directions
One potential research direction for 2-Fluorobenzotrifluoride is the investigation of its reactivity and potential applications in organic synthesis. This compound may serve as a valuable building block in the development of new pharmaceuticals, agrochemicals, or materials.
Another area worth exploring is the environmental impact of 2-Fluorobenzotrifluoride and its potential as a precursor for environmentally friendly alternatives. Research could focus on developing greener synthetic routes or studying the degradation pathways of this compound to assess its potential effects on ecosystems.
🧪 Related Compounds
One similar compound to 2-Fluorobenzotrifluoride is 2-Chlorobenzotrifluoride. In this compound, the fluorine atom in 2-Fluorobenzotrifluoride is replaced by a chlorine atom. This substitution results in a different set of chemical properties, such as changes in polarity and reactivity.
Another related compound is 2-Nitrobenzotrifluoride. In this molecule, a nitro group replaces the fluorine atom in 2-Fluorobenzotrifluoride. The addition of the nitro group introduces new functional groups that can participate in various chemical reactions, leading to different applications and properties compared to 2-Fluorobenzotrifluoride.
A third compound similar to 2-Fluorobenzotrifluoride is 2-Methylbenzotrifluoride. In this molecule, a methyl group is attached to the benzene ring instead of a fluorine atom. The presence of the methyl group can alter the steric hindrance and electronic properties of the compound, influencing its behavior in various chemical reactions and interactions.
