2-(Diisopropylamino)ethyl chloride is a chemical compound that plays a crucial role in various industries, particularly in the pharmaceutical and healthcare sectors. This compound is commonly used as a precursor in the synthesis of various medications, such as local anesthetics and antihistamines. Additionally, it is utilized in organic chemistry research and in the development of new drugs. Its relevance extends to everyday life as it contributes to the production of essential medical treatments that improve the health and well-being of individuals worldwide.
Table of Contents:
- 💡 Commercial Applications
- ⚗️ Chemical & Physical Properties
- 🏭 Production & Procurement
- ⚠️ Safety Considerations
- 🔬 Potential Research Directions
- 🧪 Related Compounds
💡 Commercial Applications
2-(Diisopropylamino)ethyl chloride, also known as N,N-diisopropylethylamine hydrochloride, has various commercial and industrial applications. One significant use is as a catalyst in the synthesis of pharmaceuticals and agrochemicals. Its ability to facilitate chemical reactions makes it valuable in the production of these crucial substances.
Additionally, this compound is utilized in the synthesis of polymers and resin systems. Its properties make it a suitable additive in coatings, adhesives, and sealants. The presence of 2-(Diisopropylamino)ethyl chloride can improve the performance and longevity of these materials, making it a desirable component in industrial applications.
In the realm of drug and medication applications, 2-(Diisopropylamino)ethyl chloride is used as an intermediate in the synthesis of various pharmaceutical compounds. It plays a crucial role in the production of certain medications, particularly those that require complex chemical processes for their creation. Its involvement in drug synthesis highlights its importance in the pharmaceutical industry.
⚗️ Chemical & Physical Properties
2-(Diisopropylamino)ethyl chloride is a colorless to pale yellow liquid with a strong, sharp odor. The odor of this compound can be described as pungent and similar to that of chloroform.
With a molar mass of 143.67 g/mol and a density of 0.881 g/cm³, 2-(Diisopropylamino)ethyl chloride is heavier than common food items like water (18.02 g/mol, 1.00 g/cm³) and sugar (342.30 g/mol, 1.59 g/cm³).
The melting point of 2-(Diisopropylamino)ethyl chloride is reported to be around -40°C, while its boiling point is approximately 113-114°C. In comparison, common food items like butter (melting point around 32-35°C) and water (boiling point at 100°C) have lower melting and boiling points.
2-(Diisopropylamino)ethyl chloride is sparingly soluble in water and has a low viscosity. This is in contrast to common food items like salt (high solubility in water) and honey (high viscosity), which exhibit different solubility and viscosity properties in aqueous solutions.
🏭 Production & Procurement
2-(Diisopropylamino)ethyl chloride is typically produced through a reaction between diisopropylamine and ethyl chloride. This reaction yields the desired product along with other side products, which must be carefully separated to obtain the pure compound.
The procurement of 2-(Diisopropylamino)ethyl chloride involves obtaining the necessary raw materials, such as diisopropylamine and ethyl chloride, from chemical suppliers. These materials are then combined in a controlled environment, utilizing proper safety precautions to ensure the reaction proceeds smoothly.
Once the 2-(Diisopropylamino)ethyl chloride is synthesized, it can be transported via standard chemical transportation methods, such as in sealed containers or drums. Special attention must be paid to the temperature and pressure conditions during transportation to prevent any potential hazards or degradation of the compound. Proper labeling and documentation are also crucial for compliance with regulations.
⚠️ Safety Considerations
Safety considerations for 2-(Diisopropylamino)ethyl chloride should be taken seriously due to its potential hazards. This compound is highly flammable and may ignite easily, so precautions should be taken to prevent exposure to sources of ignition. Additionally, it is corrosive and may cause skin and eye irritation upon contact. Proper personal protective equipment, such as gloves and safety goggles, should be worn when handling this chemical to minimize the risk of harm.
The hazard statements for 2-(Diisopropylamino)ethyl chloride include “Highly flammable liquid and vapor,” “Causes skin irritation,” “Causes serious eye irritation,” and “May cause respiratory irritation.” These statements highlight the various potential hazards associated with this compound, emphasizing the importance of handling it with caution and following proper safety protocols to prevent harm.
Precautionary statements for 2-(Diisopropylamino)ethyl chloride include “Keep away from heat/sparks/open flames/hot surfaces,” “Wear protective gloves/protective clothing/eye protection/face protection,” “IF ON SKIN: Wash with plenty of soap and water,” and “IF IN EYES: Rinse cautiously with water for several minutes.” These statements outline specific actions that should be taken to minimize the risk of harm when handling this chemical, emphasizing the importance of proper protective measures and prompt response in case of exposure.
🔬 Potential Research Directions
One potential research direction for 2-(Diisopropylamino)ethyl chloride is its application in organic synthesis reactions. Studying its reactivity and selectivity in various transformations could provide insights into new methodologies for the preparation of complex organic molecules.
Another area of interest could be investigating the pharmacological properties of 2-(Diisopropylamino)ethyl chloride. Determining its potential as a pharmaceutical agent or precursor for drug synthesis could lead to the development of novel therapeutic compounds with improved efficacy and safety profiles.
Furthermore, exploration of the chemical stability and compatibility of 2-(Diisopropylamino)ethyl chloride with other reagents and substrates could offer valuable information for its practical use in chemical processes. Understanding its behavior under different reaction conditions could help optimize its application in various synthetic protocols.
🧪 Related Compounds
One similar compound to 2-(Diisopropylamino)ethyl chloride is N,N-Diisopropylethylamine. This compound also contains a diisopropylamino group, but without the chloride functional group attached. N,N-Diisopropylethylamine is commonly used as a base in organic synthesis reactions due to its basicity and non-nucleophilic nature.
Another related compound is 2-(Dimethylamino)ethyl chloride. This compound shares a similar structure with 2-(Diisopropylamino)ethyl chloride but instead of two isopropyl groups, it has two methyl groups attached to the amino nitrogen. 2-(Dimethylamino)ethyl chloride is often used as a quaternization reagent in organic synthesis to introduce the chloride counterion to the dimethylamino group.
A further compound with a comparable structure is 2-(Diethylamino)ethyl chloride. This compound contains a diethylamino group instead of a diisopropylamino group like 2-(Diisopropylamino)ethyl chloride. 2-(Diethylamino)ethyl chloride is also utilized as a quaternization reagent in organic chemistry reactions, similar to 2-(Dimethylamino)ethyl chloride.
