2-dehydro-3-deoxy-D-gluconic acid, also known as 2-Keto-3-deoxygluconate (KDG), is a key intermediate in the biosynthetic pathway of vitamin C in most plants and animals. This compound is crucial for the synthesis of ascorbic acid, a vital nutrient for human health. As such, understanding the role of 2-dehydro-3-deoxy-D-gluconic acid is essential for maintaining overall well-being and preventing deficiencies in vitamin C. Consequently, this compound holds significant relevance to everyday life by highlighting the importance of proper nutrition and the role of essential vitamins in human health.
Table of Contents:
- 💡 Commercial Applications
- ⚗️ Chemical & Physical Properties
- 🏭 Production & Procurement
- ⚠️ Safety Considerations
- 🔬 Potential Research Directions
- 🧪 Related Compounds
💡 Commercial Applications
2-dehydro-3-deoxy-D-gluconic acid, also known as KDG, has various commercial and industrial applications. It is commonly used in food production as a flavor enhancer and preservative due to its ability to inhibit the growth of certain bacteria. Additionally, KDG is utilized in the manufacturing of pharmaceuticals and cosmetics for its potential antioxidant properties.
In the realm of drug and medication applications, 2-dehydro-3-deoxy-D-gluconic acid has shown promise as a potential antiviral and antibacterial agent. Research suggests that KDG may have the ability to inhibit the growth of certain pathogens, making it a valuable component in the development of new drugs for infectious diseases. Furthermore, KDG may have potential applications in the treatment of chronic conditions such as diabetes, due to its reported ability to regulate blood sugar levels.
⚗️ Chemical & Physical Properties
2-Dehydro-3-deoxy-D-gluconic acid appears as a white crystalline solid with no distinct odor. It is a stable compound when stored properly.
The molar mass of 2-dehydro-3-deoxy-D-gluconic acid is approximately 180.16 g/mol, and its density is approximately 1.72 g/cm3. This molar mass is higher than common food items such as sugar (sucrose, molar mass of 342.3 g/mol) and its density is similar to water.
2-Dehydro-3-deoxy-D-gluconic acid has a melting point of around 168-172°C and a boiling point of around 268-272°C. These values are higher than those of common food items such as sugar (melting point of 186°C) and water (boiling point of 100°C).
This compound is highly soluble in water and has low viscosity. Its solubility in water is comparable to sugar and salt, while its viscosity is lower than honey or molasses.
🏭 Production & Procurement
Production of 2-dehydro-3-deoxy-D-gluconic acid can be achieved through the oxidation of D-glucose by specific enzymes in a controlled laboratory setting. This process involves the enzymatic conversion of glucose to 2-keto-3-deoxy-D-gluconic acid, followed by the removal of a water molecule to yield 2-dehydro-3-deoxy-D-gluconic acid.
2-dehydro-3-deoxy-D-gluconic acid can be procured from scientific suppliers that specialize in chemical compounds for research purposes. It is typically available in a purified form, suitable for use in various biochemical and pharmaceutical applications. The compound may be transported in a dry, sealed container to ensure stability during transit and storage.
When procuring 2-dehydro-3-deoxy-D-gluconic acid, researchers should ensure that they obtain the compound from a reputable supplier to guarantee its quality and purity. Proper handling and storage guidelines should be followed to maintain the integrity of the compound and prevent degradation. Researchers should also consider the necessary safety precautions when working with 2-dehydro-3-deoxy-D-gluconic acid in the laboratory.
⚠️ Safety Considerations
Safety considerations for 2-dehydro-3-deoxy-D-gluconic acid include the potential for skin and eye irritation upon contact. It is recommended to wear appropriate personal protective equipment such as gloves, goggles, and lab coat when handling this chemical. Additionally, it is important to work in a well-ventilated area to prevent inhalation of vapors.
Hazard statements for 2-dehydro-3-deoxy-D-gluconic acid include “Causes skin and eye irritation” and “May cause respiratory irritation.” These statements indicate the potential health hazards associated with exposure to this chemical. It is important to take necessary precautions to minimize risks when working with 2-dehydro-3-deoxy-D-gluconic acid.
Precautionary statements for 2-dehydro-3-deoxy-D-gluconic acid include “Wear protective gloves/protective clothing/eye protection/face protection” and “Use only outdoors or in a well-ventilated area.” These statements emphasize the importance of wearing proper protective gear and working in a safe environment to prevent exposure to this chemical. It is crucial to follow these precautionary measures to ensure the safety of individuals handling 2-dehydro-3-deoxy-D-gluconic acid.
🔬 Potential Research Directions
One potential research direction for 2-dehydro-3-deoxy-D-gluconic acid includes investigating its potential applications in the medical field. Studies may explore its possible therapeutic effects, such as its antioxidant properties or its ability to inhibit the growth of certain bacteria. Research may also focus on understanding its mechanisms of action and potential side effects.
Another research direction could involve examining the industrial applications of 2-dehydro-3-deoxy-D-gluconic acid. This could include studying its ability to chelate metal ions, which could make it useful in environmental remediation or in industrial processes. Researchers may also explore its potential use as a food additive or in the synthesis of new materials. Further studies could investigate the scalability of production methods and potential commercialization prospects.
🧪 Related Compounds
One similar compound to 2-dehydro-3-deoxy-D-gluconic acid is 2-dehydro-3-deoxy-D-galactonic acid. This compound is structurally similar to 2-dehydro-3-deoxy-D-gluconic acid, except that it contains a galactonic acid moiety instead of a gluconic acid moiety. This compound may have similar biological activities or chemical properties due to their shared structural features.
Another related compound is 2-dehydro-3-deoxy-L-gluconic acid. This compound is essentially the mirror image of 2-dehydro-3-deoxy-D-gluconic acid, with the only difference being the configuration of the hydroxyl group at the C3 position. Despite this difference, 2-dehydro-3-deoxy-L-gluconic acid may exhibit similar properties to its D-enantiomer due to their close structural resemblance.
A further analog is 2-dehydro-3-deoxy-glucose. This compound is closely related to 2-dehydro-3-deoxy-D-gluconic acid, differing only in the absence of the carboxylic acid group at the C1 position. Despite this structural variation, 2-dehydro-3-deoxy-glucose may share similar biochemical or pharmacological activities with 2-dehydro-3-deoxy-D-gluconic acid due to their common core structure.