Compound Profile

2-Chloropropionic acid 

2

2-Chloropropionic acid is a chemical compound that plays a crucial role in various industries and applications. It is commonly used in the production of pharmaceuticals, agrochemicals, and other specialty chemicals. This compound is also utilized as a building block in the synthesis of various organic compounds, making it a key ingredient in the manufacturing of a wide range of products. Its relevance to everyday life lies in its role in the production of essential goods and materials that we commonly rely on in our daily lives.

Table of Contents:

💡  Commercial Applications

2-Chloropropionic acid, also known as 2-chloropropanoic acid, has various commercial and industrial applications. It is commonly used as a building block in the synthesis of pharmaceuticals, agrochemicals, and other organic compounds. Additionally, it is utilized in the production of herbicides, insecticides, and other chemical products due to its reactivity and versatility.

In the realm of drug and medication applications, 2-Chloropropionic acid plays a crucial role in the synthesis of various pharmaceutical compounds. It is used as a starting material for the production of drugs such as ibuprofen, which is a nonsteroidal anti-inflammatory drug (NSAID) commonly used to relieve pain and reduce inflammation. The acid’s chemical properties make it a valuable precursor in the pharmaceutical industry for the development of new medications and treatments.

Furthermore, 2-Chloropropionic acid is employed in the production of various medications used in the treatment of neurological disorders and mental health conditions. It serves as a key intermediate in the synthesis of gamma-aminobutyric acid (GABA), an important neurotransmitter in the central nervous system. This acid derivative is utilized in the manufacturing of drugs that modulate GABA receptors, contributing to the management of conditions such as epilepsy, anxiety, and insomnia.

⚗️  Chemical & Physical Properties

2-Chloropropionic acid is a colorless liquid with a pungent odor. It is soluble in water and ethanol, and its stability is affected by exposure to air and light.

The molar mass of 2-Chloropropionic acid is approximately 108.52 g/mol, with a density of about 1.316 g/cm3. This places it on par with common food items such as sucrose (molar mass of 342.30 g/mol, density of 1.587 g/cm3).

The melting point of 2-Chloropropionic acid is around -11°C, while the boiling point is around 164-165°C. In comparison, common food items like butter have a melting point of around 32-35°C and a boiling point of around 150-200°C.

2-Chloropropionic acid is soluble in water but exhibits high viscosity. This sets it apart from common food items like salt, which are highly soluble in water but have low viscosity.

🏭  Production & Procurement

2-Chloropropionic acid, a chemical compound also known as alpha-chloropropionic acid, is typically produced through the chlorination of propionic acid. This reaction involves the addition of chlorine gas, resulting in the substitution of a hydrogen atom with a chlorine atom at the alpha position of the propionic acid molecule. The process is carried out under specific conditions to ensure the formation of 2-Chloropropionic acid as the desired product.

The procurement of 2-Chloropropionic acid involves obtaining the chemical compound from manufacturers or chemical suppliers. It is commonly available in liquid form, packaged in containers suitable for transportation and storage. Due to its corrosive nature, proper precautions must be taken when handling and transporting 2-Chloropropionic acid to prevent spills or exposure to skin and eyes. Specialized equipment and storage facilities may be required to ensure safe handling of the compound.

Once procured, 2-Chloropropionic acid can be transported using appropriate vessels such as chemical drums or tanks, depending on the quantity and specific requirements for transport. Careful consideration must be given to regulatory guidelines governing the transportation of hazardous chemicals to ensure compliance with safety standards. Proper labeling and documentation are essential to facilitate the safe and efficient transport of 2-Chloropropionic acid from the manufacturer to the end-user.

⚠️  Safety Considerations

Safety considerations for 2-Chloropropionic acid include its classification as a harmful substance that can cause skin irritation, serious eye damage, and respiratory irritation. It is important to handle this chemical with caution, wearing appropriate personal protective equipment such as gloves, goggles, and respiratory protection. In case of contact with skin or eyes, immediate medical attention should be sought, and contaminated clothing should be removed.

Hazard statements for 2-Chloropropionic acid include “causes skin irritation,” “causes serious eye damage,” and “may cause respiratory irritation.” These statements highlight the potential dangers associated with exposure to this chemical, emphasizing the importance of taking proper precautions when handling it. It is essential to minimize the risk of skin, eye, and respiratory contact with 2-Chloropropionic acid to prevent harmful effects on health.

Precautionary statements for 2-Chloropropionic acid include “wear protective gloves/protective clothing/eye protection/face protection,” “IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water/shower,” and “IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.” These statements provide specific instructions on how to safely handle 2-Chloropropionic acid to minimize the risk of exposure and prevent adverse health effects. Adhering to these precautions is crucial to maintaining a safe working environment when dealing with this chemical.

🔬  Potential Research Directions

Potential research directions for 2-Chloropropionic acid may include investigating its use as a precursor in the synthesis of pharmaceutical compounds. Researchers may also explore its role in various chemical reactions and organic transformations to develop new synthetic methodologies. Additionally, studies could focus on the environmental impact of 2-Chloropropionic acid and its degradation pathways in different ecosystems.

Furthermore, investigations into the toxicological effects of 2-Chloropropionic acid on human health and the environment could be a key research direction. Understanding its mechanism of action and potential hazards can provide valuable insights for risk assessment and regulatory considerations. Additionally, exploring the possibility of developing safer derivatives or alternative synthetic routes for 2-Chloropropionic acid could be of interest to researchers in the field.

Moreover, studies on the physicochemical properties and reactivity of 2-Chloropropionic acid under different conditions could offer insights into its potential applications in various industries. Researchers may also delve into the catalytic reactions involving 2-Chloropropionic acid to enhance the efficiency and selectivity of chemical transformations. Overall, further research on 2-Chloropropionic acid can contribute to expanding our knowledge in organic chemistry, toxicology, and environmental science.

One similar compound to 2-Chloropropionic acid is 2-Bromopropionic acid. This compound has a similar molecular structure to 2-Chloropropionic acid, with a bromine atom in place of the chlorine atom. Like 2-Chloropropionic acid, 2-Bromopropionic acid is a colorless liquid that is slightly soluble in water.

Another compound similar to 2-Chloropropionic acid is 2-Iodopropionic acid. This compound has the same molecular formula as 2-Chloropropionic acid, but with an iodine atom in place of the chlorine atom. 2-Iodopropionic acid is also a colorless liquid, but it is more soluble in water than 2-Chloropropionic acid.

A third similar compound to 2-Chloropropionic acid is 2-Fluoropropionic acid. This compound has a fluorine atom in place of the chlorine atom in its molecular structure. Like 2-Chloropropionic acid, 2-Fluoropropionic acid is a colorless liquid that is slightly soluble in water. Each of these compounds shares a similar molecular structure with 2-Chloropropionic acid, differing only in the halogen atom present in the molecule.

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