2-Chloro-4-nitrobenzoic acid 

2-Chloro-4-nitrobenzoic acid is a chemical compound that may not have direct relevance to everyday life for most individuals. However, it plays a crucial role in various industries, including pharmaceuticals, agriculture, and materials science. This compound is used in the synthesis of numerous drugs, pesticides, and dyes, making it a key component in the development of products that impact our daily lives. Additionally, its unique chemical properties make it valuable in research and development for a wide range of applications.

Table of Contents:

💡  Commercial Applications

2-Chloro-4-nitrobenzoic acid, a compound derived from benzoic acid, finds commercial and industrial applications due to its unique properties. It is commonly used in the manufacture of dyes, pigments, and pharmaceuticals. Additionally, this compound serves as an intermediate in the synthesis of various organic chemicals, making it a valuable commodity in the chemical industry.

In terms of drug and medication applications, 2-Chloro-4-nitrobenzoic acid is used in the production of certain pharmaceutical compounds. Specifically, it can be utilized as a building block for the synthesis of active pharmaceutical ingredients (APIs) in the pharmaceutical industry. Its chemical structure allows for modifications that enhance the bioavailability and efficacy of drugs, making it a crucial component in drug development and formulation processes.

⚗️  Chemical & Physical Properties

2-Chloro-4-nitrobenzoic acid is a white crystalline solid with a slight odor. Its appearance is similar to many other organic compounds.

The molar mass of 2-Chloro-4-nitrobenzoic acid is 205.54 g/mol, and its density is 1.66 g/cm^3. This makes it more dense than common food items such as water (molar mass of 18.02 g/mol, density of 1 g/cm^3) and sugar (molar mass of 342.3 g/mol, density of 1.59 g/cm^3).

2-Chloro-4-nitrobenzoic acid has a melting point of 177-178°C and a boiling point of 344°C. This is significantly higher than common food items such as butter (melting point of 32-35°C, boiling point of 150°C) and salt (melting point of 801°C, boiling point of 1,413°C).

2-Chloro-4-nitrobenzoic acid is sparingly soluble in water and has a low viscosity. This differs from common food items such as sugar (high solubility in water) and honey (high viscosity).

🏭  Production & Procurement

2-Chloro-4-nitrobenzoic acid is typically produced through the nitration of 2-chlorobenzoic acid, a process that involves treating the compound with a mixture of concentrated sulfuric acid and nitric acid. This reaction results in the substitution of a nitro group (-NO2) at the para position of the benzene ring, ultimately forming 2-Chloro-4-nitrobenzoic acid.

The procurement of 2-Chloro-4-nitrobenzoic acid involves sourcing the compound from chemical suppliers or manufacturers specialized in producing nitrobenzoic acids. The compound is typically available in the form of a solid powder or crystalline substance. Once procured, 2-Chloro-4-nitrobenzoic acid can be transported in sealed containers or drums to ensure its stability and prevent potential contamination during transit.

During transportation, it is crucial to handle 2-Chloro-4-nitrobenzoic acid with care, as it is considered a hazardous chemical due to its potential irritant and toxic properties. Proper labeling, packaging, and handling procedures in accordance with regulatory guidelines must be observed to ensure the safe transport of the compound. Moreover, storing and transporting 2-Chloro-4-nitrobenzoic acid in a controlled environment, away from heat sources and incompatible substances, is essential to maintain its integrity and prevent any potential hazards.

⚠️  Safety Considerations

Safety considerations for 2-Chloro-4-nitrobenzoic acid include its potential for causing irritation to the skin, eyes, and respiratory tract upon contact. It is important to handle this compound with care, using appropriate personal protective equipment such as gloves and goggles. In case of accidental exposure, it is crucial to wash affected areas thoroughly with water and seek medical attention if necessary.

This compound should be stored in a well-ventilated area away from sources of ignition or heat. It is important to avoid prolonged exposure to 2-Chloro-4-nitrobenzoic acid and to limit its release into the environment. Proper labeling and handling procedures should be followed to prevent any accidents or contamination.

Hazard statements for 2-Chloro-4-nitrobenzoic acid include its potential to cause skin irritation, serious eye damage, and respiratory irritation upon contact. It is also classified as harmful if swallowed or inhaled. This compound may cause damage to organs through prolonged or repeated exposure, and it is important to handle it with caution to prevent any adverse health effects.

Precautionary statements for 2-Chloro-4-nitrobenzoic acid include the need to wear protective gloves, clothing, and eye protection when handling this compound. It is recommended to work in a well-ventilated area and avoid breathing its vapors. In case of skin contact, the affected area should be washed with soap and water, and in case of eye contact, rinsing with water should be done immediately. It is also crucial to store this compound in a tightly closed container in a well-ventilated area away from incompatible substances.

🔬  Potential Research Directions

Potential research directions for 2-Chloro-4-nitrobenzoic acid may include studies on its chemical reactivity and pharmacological properties. Research into its potential uses as a building block in organic synthesis or as a precursor for the preparation of biologically active molecules could also be of interest.

Furthermore, investigations into the environmental fate and toxicity of 2-Chloro-4-nitrobenzoic acid could be valuable for understanding its impact on ecosystems and human health. Studies on its degradation pathways, persistence in the environment, and potential bioaccumulation in organisms could provide important insights.

Additionally, research on the potential applications of 2-Chloro-4-nitrobenzoic acid in various industries such as pharmaceuticals, agrochemicals, or materials science may be warranted. Evaluating its potential as a key intermediate in the synthesis of new drugs, pesticides, or advanced materials could lead to the discovery of novel compounds with beneficial properties.

One similar compound to 2-Chloro-4-nitrobenzoic acid is 2-Chloro-3-nitrobenzoic acid. This compound differs from the original in the position of the nitro group, which is located on the 3-carbon instead of the 4-carbon. This slight alteration in structure can lead to differences in reactivity and biological activity.

Another analogous compound is 2-Chloro-4-methylbenzoic acid. In this compound, a methyl group replaces the nitro group present in 2-Chloro-4-nitrobenzoic acid. This substitution can impact the compound’s physical and chemical properties, such as melting point and solubility, as well as its biological activity.

A further similar compound is 3-Chloro-4-nitrobenzoic acid. In this case, the chlorine atom is positioned on the 3-carbon instead of the 2-carbon, while the nitro group remains in the 4-carbon position. This slight change in structure can lead to alterations in the compound’s reactivity and interactions with other molecules.

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