2-Aminothiophenol is a compound that possesses valuable properties in various industries, particularly in the field of organic chemistry. This compound is used in the manufacturing of pharmaceuticals, agrochemicals, and pigments. It also serves as a precursor in the synthesis of other important compounds. Due to its versatility and wide range of applications, 2-Aminothiophenol plays a significant role in everyday life by contributing to the development of essential products that impact society’s health, agriculture, and aesthetics.
Table of Contents:
- 💡 Commercial Applications
- ⚗️ Chemical & Physical Properties
- 🏭 Production & Procurement
- ⚠️ Safety Considerations
- 🔬 Potential Research Directions
- 🧪 Related Compounds
💡 Commercial Applications
2-Aminothiophenol has various commercial and industrial applications. It is commonly used in the manufacture of dyes, pigments, and pharmaceuticals due to its ability to act as a building block for constructing complex molecules. Additionally, it can be utilized as a corrosion inhibitor in metalworking processes.
In the realm of drug and medication applications, 2-Aminothiophenol has been studied for its potential therapeutic properties. Research has shown that this compound exhibits antioxidant and anti-inflammatory effects, suggesting that it could be beneficial for treating conditions such as arthritis and other inflammatory diseases. Furthermore, its chemical structure makes it a promising candidate for the development of new pharmaceuticals targeting specific biological pathways.
⚗️ Chemical & Physical Properties
2-Aminothiophenol is a white solid with a characteristic foul odor, similar to that of rotten eggs. This compound is commonly used in organic synthesis and pharmaceutical manufacturing due to its reactivity and distinct aroma.
With a molar mass of 125.16 g/mol and a density of 1.3 g/cm³, 2-Aminothiophenol has similar properties to common food items such as sugar and salt in terms of molar mass and density. However, its chemical properties differ significantly, making it unsuitable for consumption.
The melting point of 2-Aminothiophenol is approximately 38°C, while its boiling point is around 131°C. Compared to common food items like butter or chocolate, which melt at higher temperatures, this compound has lower melting and boiling points, indicative of its volatile nature.
2-Aminothiophenol is sparingly soluble in water and has a relatively low viscosity. In contrast, common food items like sugar or salt dissolve readily in water and exhibit a higher viscosity. These differences in solubility and viscosity highlight the unique chemical properties of 2-Aminothiophenol compared to everyday food items.
🏭 Production & Procurement
2-Aminothiophenol, a key intermediate in the synthesis of pharmaceuticals and agrochemicals, is typically produced through the reaction of aniline with carbon disulfide and sodium hydroxide. This process, known as the Zincke reaction, results in the formation of 2-Aminothiophenol as a yellow solid, which can be further purified through recrystallization.
2-Aminothiophenol can be procured from chemical suppliers or pharmaceutical companies that specialize in the production of fine chemicals. It is commonly transported in sealed containers or drums to prevent exposure to moisture or air, which can degrade the quality of the compound. Due to its sensitivity to light and air, 2-Aminothiophenol should be stored in a cool, dry place away from direct sunlight.
Care should be taken when handling and transporting 2-Aminothiophenol, as it is considered a hazardous chemical that can cause skin and eye irritation upon contact. Proper safety precautions, such as the use of gloves and protective eyewear, should be followed to minimize the risk of exposure. Additionally, regulatory guidelines regarding the handling and transportation of hazardous chemicals should be strictly adhered to in order to ensure the safe and efficient procurement of 2-Aminothiophenol.
⚠️ Safety Considerations
Safety considerations for 2-Aminothiophenol involve its potential hazards when handling, storing, or using the compound. As an aromatic amine, 2-Aminothiophenol is known to have mutagenic and carcinogenic properties. It may cause irritation to the skin, eyes, and respiratory tract upon contact or inhalation. In addition, exposure to 2-Aminothiophenol should be limited to avoid adverse health effects.
The hazard statements for 2-Aminothiophenol include warnings about its potential mutagenic and carcinogenic properties. It is advised to handle the compound with caution and to avoid direct contact with the skin, eyes, and respiratory system. Any spills or leaks should be contained and properly cleaned up to prevent exposure. Adequate personal protective equipment should be worn when working with 2-Aminothiophenol to minimize risks of adverse health effects.
Precautionary statements for 2-Aminothiophenol recommend storing the compound in a well-ventilated area away from heat sources and incompatible materials. It is important to keep the substance tightly sealed in its original container and to avoid exposure to moisture. When working with 2-Aminothiophenol, it is crucial to use appropriate personal protective equipment, such as gloves, goggles, and a lab coat. In case of accidental exposure, immediate medical attention should be sought.
🔬 Potential Research Directions
One potential research direction for 2-Aminothiophenol is its role as a building block for the synthesis of various organic compounds. By exploring different reaction pathways and conditions, researchers can investigate the versatility of this molecule in forming new chemical structures.
Another promising research avenue is the study of the biological activities of 2-Aminothiophenol and its derivatives. Understanding how this compound interacts with biological systems could lead to the development of new pharmaceuticals or agrochemicals with specific molecular targets.
Furthermore, investigating the photophysical properties of 2-Aminothiophenol could provide insights into its potential applications in optoelectronic devices or sensors. By studying its absorption and emission spectra, researchers can explore the compound’s potential as a fluorescent probe or photosensitizer in various technological fields.
🧪 Related Compounds
One similar compound to 2-Aminothiophenol based upon molecular structure is 2-Mercaptoaniline. This compound contains a sulfur atom in the phenyl ring and an amino group attached to the sulfur atom, similar to the structure of 2-Aminothiophenol. 2-Mercaptoaniline is commonly used in organic synthesis and chemical research due to its ability to undergo various reactions to form diverse chemical products.
Another similar compound is 2-Aminobenzothiol. This compound also contains a sulfur atom in the phenyl ring, similar to 2-Aminothiophenol. However, 2-Aminobenzothiol has a benzene ring instead of a thiophene ring. 2-Aminobenzothiol is often used in pharmaceutical research and as a building block in organic synthesis due to its ability to form stable complexes with various metal ions.
Additionally, 2-Aminobenzothiazole is a compound similar to 2-Aminothiophenol. It contains a nitrogen atom and a sulfur atom in a benzothiazole ring, which is structurally related to the thiophene ring in 2-Aminothiophenol. 2-Aminobenzothiazole is known for its application in the synthesis of various heterocyclic compounds and its use as a corrosion inhibitor in metal surfaces due to its ability to form stable complexes with metal ions.