2-Amino-4-methylpyrimidine, a compound belonging to the pyrimidine family, plays a significant role in various industries and products that impact everyday life. This compound serves as a key building block in the synthesis of pharmaceuticals, agrochemicals, and materials such as polymers and dyes. In the pharmaceutical sector, it is utilized in the production of various medications, including antiviral drugs and nucleoside analogues. Additionally, 2-Amino-4-methylpyrimidine is employed in the development of herbicides and pesticides in the agricultural sector. Its versatile applications make it a crucial component in enhancing and improving various aspects of daily life.
Table of Contents:
- 💡 Commercial Applications
- ⚗️ Chemical & Physical Properties
- 🏭 Production & Procurement
- ⚠️ Safety Considerations
- 🔬 Potential Research Directions
- 🧪 Related Compounds
💡 Commercial Applications
2-Amino-4-methylpyrimidine has several commercial and industrial applications. It is commonly used as a building block in the synthesis of pharmaceuticals, agrochemicals, and dyes. This compound can also be utilized in the production of photoinitiators for photopolymerization processes in the printing and coatings industries.
In terms of drug and medication applications, 2-Amino-4-methylpyrimidine is an important intermediate in the synthesis of various pharmaceutical compounds. It serves as a key component in the production of antiviral drugs, such as acyclovir, which is used to treat herpes simplex virus infections. Additionally, this compound can be used in the synthesis of anti-inflammatory medications and other pharmaceuticals for a variety of medical conditions.
⚗️ Chemical & Physical Properties
2-Amino-4-methylpyrimidine is a white crystalline solid with no distinct odor. It is a compound that is often used in pharmaceutical and agricultural applications.
This chemical compound has a molar mass of 110.12 g/mol and a density of 1.124 g/cm3. Compared to common food items, such as sugar with a molar mass of 342.3 g/mol and a density of 1.59 g/cm3, 2-Amino-4-methylpyrimidine is relatively lighter and less dense.
The melting point of 2-Amino-4-methylpyrimidine is approximately 68-73°C, and its boiling point is around 296-303°C. In comparison, common food items like butter have a melting point of 32-35°C and a boiling point of 150°C. This compound has higher melting and boiling points than most food items.
2-Amino-4-methylpyrimidine is sparingly soluble in water and has a low viscosity. Compared to common food items like salt, which is highly soluble in water and has a higher viscosity, this compound displays lower solubility and viscosity in water.
🏭 Production & Procurement
2-Amino-4-methylpyrimidine, also known as AMPY, is typically produced through chemical synthesis methods. The most common approach involves the reaction of 2,4-dichloro-6-methylpyrimidine with ammonia, resulting in AMPY as the final product. This process is carried out in specialized laboratories under controlled conditions to ensure high purity and yield.
In order to procure 2-Amino-4-methylpyrimidine, one must rely on suppliers who carry this chemical compound. Various chemical manufacturers and distributors offer AMPY for sale in bulk quantities. Once procured, the compound can be transported in sealed containers to prevent contamination or degradation during transit.
Care must be taken when handling and transporting 2-Amino-4-methylpyrimidine due to its potential health hazards. Proper safety equipment, such as gloves and goggles, should be worn during the handling of the compound. Additionally, strict regulations regarding the transportation of hazardous chemicals must be followed to ensure the safe delivery of the product to its intended destination.
⚠️ Safety Considerations
Safety considerations for 2-Amino-4-methylpyrimidine should first and foremost include measures to prevent inhalation, skin contact, and ingestion. This compound is classified as harmful if swallowed, inhaled, or in contact with skin, so personal protective equipment such as gloves, goggles, and a lab coat should be worn at all times when handling it. In addition, it is important to work with 2-Amino-4-methylpyrimidine in a well-ventilated area to minimize exposure to its potentially harmful effects.
Furthermore, proper storage and disposal of 2-Amino-4-methylpyrimidine is essential to ensure the safety of laboratory workers and the environment. This compound should be stored in a dry, cool, and well-ventilated area away from incompatible substances, such as oxidizing agents and acids. Any unused or expired 2-Amino-4-methylpyrimidine should be disposed of according to local regulations for hazardous waste, to prevent accidental exposure and contamination of the surrounding area.
Hazard statements for 2-Amino-4-methylpyrimidine include the potential for causing skin irritation, serious eye irritation, and being harmful if swallowed. This compound may also cause respiratory irritation if inhaled. It is important to avoid breathing in dust, vapor, mist, or gas from 2-Amino-4-methylpyrimidine, as well as to avoid contact with skin and eyes. In case of ingestion, immediate medical attention should be sought, and the individual should not induce vomiting unless instructed to do so by medical personnel.
Precautionary statements for 2-Amino-4-methylpyrimidine should include wearing suitable protective clothing, gloves, and eye/face protection when handling this compound. It is important to work in a well-ventilated area, and to avoid breathing in dust/fume/gas/mist/vapors when using 2-Amino-4-methylpyrimidine. In case of skin contact, the affected area should be washed thoroughly with soap and water. In case of eye contact, the eyes should be rinsed cautiously with water for several minutes, while removing contact lenses if present and seeking medical advice if irritation persists.
🔬 Potential Research Directions
Research on 2-Amino-4-methylpyrimidine, a heterocyclic compound, may focus on its pharmacological properties and potential therapeutic applications. Studies could explore its interactions with biological targets and its potential as a drug candidate for various medical conditions.
Another research direction could involve the synthesis of derivatives of 2-Amino-4-methylpyrimidine to improve its biological activity and specificity. By modifying its chemical structure, researchers can investigate how these changes impact its pharmacological profile, opening up avenues for the development of novel pharmaceutical agents.
Furthermore, investigations into the pharmacokinetics and pharmacodynamics of 2-Amino-4-methylpyrimidine could shed light on its absorption, distribution, metabolism, and excretion in the body. Understanding these aspects is crucial for assessing its safety and efficacy as a potential drug candidate.
🧪 Related Compounds
One similar compound to 2-Amino-4-methylpyrimidine is 2-Amino-4-ethylpyrimidine. In this compound, the methyl group of 2-Amino-4-methylpyrimidine is replaced by an ethyl group. This substitution results in a similar molecular structure with an ethyl side chain instead of a methyl one.
Another related compound is 2-Amino-4-propylpyrimidine. In this compound, the methyl group of 2-Amino-4-methylpyrimidine is substituted by a propyl group. This change in side chain length alters the physical and chemical properties of the compound while maintaining the pyrimidine core structure.
A third compound similar to 2-Amino-4-methylpyrimidine is 2-Amino-4-isopropylpyrimidine. Here, the methyl group is replaced by an isopropyl group, resulting in a structural variant with a branched side chain. This modification impacts the compound’s reactivity and biological activity, while still preserving the pyrimidine base structure.
