2-Amino-4-methylbenzothiazole is a compound that plays a significant role in various industries, including pharmaceutical, chemical, and food production. This compound is commonly used in the synthesis of pharmaceutical drugs, dyes, and pesticides. In the pharmaceutical industry, it is utilized in the creation of anti-inflammatory medications and antibiotics. Additionally, 2-Amino-4-methylbenzothiazole is commonly found in hair dyes and certain food products as a colorant. Its presence is crucial in everyday products and processes that impact daily life.
Table of Contents:
- 💡 Commercial Applications
- ⚗️ Chemical & Physical Properties
- 🏭 Production & Procurement
- ⚠️ Safety Considerations
- 🔬 Potential Research Directions
- 🧪 Related Compounds
💡 Commercial Applications
2-Amino-4-methylbenzothiazole, a chemical compound with various industrial and commercial applications, finds use as a key intermediate in the synthesis of dyes, pigments, and pharmaceutical compounds. Its high reactivity and versatile chemical properties make it ideal for producing a wide range of products in the chemical industry.
In the commercial and industrial sectors, 2-Amino-4-methylbenzothiazole is commonly employed in the production of hair dyes, leather dyes, and optical brighteners due to its ability to impart vivid and long-lasting color to various materials. Additionally, it is utilized in the manufacturing of rubber accelerators, pesticide intermediates, and corrosion inhibitors, thereby playing a crucial role in diverse industrial processes.
In the realm of pharmaceuticals, 2-Amino-4-methylbenzothiazole serves as a valuable building block for synthesizing biologically active compounds, such as anticancer agents, antifungal medications, and antihistamines. Its structural versatility and pharmacological potential make it a valuable tool in drug discovery and development, highlighting its significance in the field of medicine.
⚗️ Chemical & Physical Properties
2-Amino-4-methylbenzothiazole is a white crystalline powder with a faint odor. It can be described as odorless to slightly aromatic when exposed to air.
The molar mass of 2-Amino-4-methylbenzothiazole is 171.21 g/mol, with a density of approximately 1.34 g/cm³. When compared to common food items, this compound has a higher molar mass and density than most food materials.
The melting point of 2-Amino-4-methylbenzothiazole is around 149-151°C, while the boiling point is approximately 355°C. These values are significantly higher compared to typical food items, which generally melt and boil at lower temperatures.
2-Amino-4-methylbenzothiazole is sparingly soluble in water, with a low viscosity. In comparison to common food items, this compound exhibits lower solubility in water and lower viscosity than most food materials.
🏭 Production & Procurement
2-Amino-4-methylbenzothiazole is typically produced through a reaction involving 2-aminobenzothiazole and formaldehyde with the presence of hydrogen chloride gas. This chemical synthesis method allows for the controlled formation of the desired compound with high purity.
2-Amino-4-methylbenzothiazole can be procured from specialized chemical suppliers that provide custom synthesis services or from larger chemical manufacturers that produce this compound in bulk quantities. The procurement process involves placing an order with the supplier and arranging for the transportation of the compound to the desired location.
The transportation of 2-Amino-4-methylbenzothiazole is typically conducted using specialized chemical transportation services that comply with safety regulations for handling hazardous materials. The compound may be transported in sealed containers or drums to prevent leakage and ensure the integrity of the product during transit.
⚠️ Safety Considerations
Safety considerations for 2-Amino-4-methylbenzothiazole must be taken seriously due to its potential hazards. This chemical should be handled with care to avoid skin and eye irritation. It is important to use appropriate personal protective equipment such as gloves, goggles, and a lab coat when working with this compound. Additionally, proper ventilation is necessary to prevent inhalation of fumes.
It is crucial to be aware of the hazard statements associated with 2-Amino-4-methylbenzothiazole. This chemical is harmful if swallowed, causing irritation of the respiratory tract. It may also cause skin and eye irritation upon contact. Furthermore, it has the potential to cause long-term adverse effects in aquatic environments.
Precautionary statements for 2-Amino-4-methylbenzothiazole are imperative to ensure safe handling and storage. It is important to keep this chemical out of reach of children and pets. Proper storage in a well-ventilated area away from heat sources is recommended. In case of spillage, it is crucial to clean up the area immediately and dispose of the waste according to local regulations. Personal protective equipment should always be worn when handling this compound to minimize risks.
🔬 Potential Research Directions
One potential research direction for 2-Amino-4-methylbenzothiazole is its use as a building block in the synthesis of various heterocyclic compounds with potential biological activity. This could involve exploring the reactivity of the amine and thiazole functional groups to create new chemical entities for drug discovery.
Another avenue of research could focus on the development of 2-Amino-4-methylbenzothiazole derivatives as fluorescent probes for biological imaging applications. By modifying the molecular structure to enhance the fluorescence properties, researchers could create tools for studying cellular processes and interactions in living systems.
Furthermore, investigation into the pharmacological properties of 2-Amino-4-methylbenzothiazole derivatives could lead to the discovery of new therapeutic agents with potential applications in treating various diseases. Studies could explore the compound’s effects on specific biological targets or pathways to elucidate its mechanism of action and potential benefits in clinical settings.
🧪 Related Compounds
One similar compound to 2-Amino-4-methylbenzothiazole based upon molecular structure is 2-Amino-4-ethylbenzothiazole. This compound differs from 2-Amino-4-methylbenzothiazole in that it has an ethyl group attached to the benzothiazole ring instead of a methyl group. This substitution alters the physical and chemical properties of the compound, leading to potential differences in reactivity and biological activity.
Another comparable compound is 2-Amino-4-propylbenzothiazole. In this compound, a propyl group is attached to the benzothiazole ring, differentiating it from both 2-Amino-4-methylbenzothiazole and 2-Amino-4-ethylbenzothiazole. The presence of the longer propyl chain may result in distinct stereochemical effects and interactions with other molecules, impacting its overall behavior and use in various applications.
A further noteworthy compound is 2-Amino-4-chlorobenzothiazole. Unlike the aforementioned compounds, this variant contains a chlorine atom instead of a methyl, ethyl, or propyl group. The introduction of a halogen atom can significantly alter the compound’s properties, influencing its solubility, stability, and biological activity. This unique structural feature may enable 2-Amino-4-chlorobenzothiazole to exhibit distinct pharmacological effects or chemical reactivities compared to its alkyl-substituted counterparts.