2-Amino-2-phenylacetic acid, also known as phenylalanine, is a vital amino acid that plays a crucial role in maintaining proper brain function and regulating mood. This amino acid is a building block of proteins and is found in various foods such as meat, fish, eggs, dairy products, and certain plant-based sources. Phenylalanine is particularly important for the production of neurotransmitters like dopamine, norepinephrine, and serotonin, which are responsible for regulating emotions, focus, and overall mental well-being. Deficiencies in phenylalanine can lead to mood disorders, cognitive impairments, and other neurological complications. Therefore, ensuring an adequate intake of phenylalanine through a balanced diet is essential for supporting optimal brain function and emotional health in everyday life.
Table of Contents:
- 💡 Commercial Applications
- ⚗️ Chemical & Physical Properties
- 🏭 Production & Procurement
- ⚠️ Safety Considerations
- 🔬 Potential Research Directions
- 🧪 Related Compounds
💡 Commercial Applications
2-Amino-2-phenylacetic acid, also known as phenylglycine, has several commercial and industrial applications. It is commonly used in the synthesis of pharmaceuticals and agrochemicals, serving as a building block for various molecules. Additionally, it is utilized in the production of chiral intermediates for the pharmaceutical industry, which are essential for the synthesis of certain types of drugs. Due to its versatile nature, 2-Amino-2-phenylacetic acid is a valuable compound in the chemical industry.
In the realm of drug and medication applications, 2-Amino-2-phenylacetic acid plays a crucial role in the synthesis of various pharmaceuticals. It is particularly important in the production of antibiotics, antiviral drugs, and non-steroidal anti-inflammatory medications. The compound’s ability to serve as a building block for these types of drugs highlights its significance in the pharmaceutical industry. Moreover, its chiral properties make it a key component in the synthesis of enantiomerically pure pharmaceuticals, which are necessary for specific drug formulations.
The commercial and industrial applications of 2-Amino-2-phenylacetic acid extend beyond the pharmaceutical sector. It is also utilized in the manufacturing of fine chemicals, dyes, and pigments. Additionally, the compound finds use in the production of fragrances and flavoring agents, contributing to various consumer products. Its versatility and importance in different industries make 2-Amino-2-phenylacetic acid a valuable compound with diverse applications.
⚗️ Chemical & Physical Properties
2-Amino-2-phenylacetic acid, also known as β-phenylalanine, is a white crystalline powder with no distinct odor. It is a solid substance at room temperature.
The molar mass of 2-Amino-2-phenylacetic acid is approximately 165.19 g/mol, and its density is around 1.21 g/cm³. When compared to common food items, such as sugar or salt, it has a higher molar mass and lower density.
The melting point of 2-Amino-2-phenylacetic acid is about 218-220°C, while the boiling point is approximately 215-218°C. In comparison to common food items, it has a higher melting point and lower boiling point.
2-Amino-2-phenylacetic acid is soluble in water, and has a low viscosity. When compared to common food items, it has similar solubility in water but lower viscosity.
🏭 Production & Procurement
2-Amino-2-phenylacetic acid, also known as alpha-phenylglycine, is typically produced through a multi-step synthesis process involving the reaction of an amino acid with an aryl halide. This reaction results in the formation of the desired compound, which is then further purified and isolated through various chemical techniques. The overall production of 2-Amino-2-phenylacetic acid requires a high level of chemical expertise and precision.
In terms of procurement, 2-Amino-2-phenylacetic acid can be sourced from specialized chemical suppliers who produce and distribute various chemical compounds for research and industrial purposes. The compound is typically available in both liquid and solid forms, depending on the specific requirements of the end user. Due to the potential hazards associated with handling certain chemicals, proper safety precautions must be observed during transport and storage of 2-Amino-2-phenylacetic acid.
Transportation of 2-Amino-2-phenylacetic acid is typically carried out in accordance with established guidelines for the handling and transport of hazardous chemical substances. The compound may be shipped in sealed containers that are labeled with appropriate safety information and handling instructions to ensure safe and secure delivery. It is important to comply with all regulatory requirements and safety protocols when transporting 2-Amino-2-phenylacetic acid to minimize the risk of accidents and ensure the integrity of the compound.
⚠️ Safety Considerations
Safety considerations for 2-Amino-2-phenylacetic acid should be taken seriously due to its potential hazards. This compound may cause skin and eye irritation upon contact, and inhalation of its dust or vapors may result in respiratory irritation. It is important to wear appropriate personal protective equipment, including gloves, goggles, and a lab coat, when handling this substance. Additionally, 2-Amino-2-phenylacetic acid should be stored in a cool, dry place away from incompatible materials and sources of ignition.
The hazard statements for 2-Amino-2-phenylacetic acid include “Causes skin and eye irritation” and “May cause respiratory irritation.” These statements indicate the potential risks associated with exposure to this compound. It is important to handle 2-Amino-2-phenylacetic acid with care to minimize the likelihood of adverse effects on health and safety.
Precautionary statements for 2-Amino-2-phenylacetic acid include “Wear protective gloves/eye protection/face protection” and “Wash hands and face thoroughly after handling.” These precautions are essential for minimizing the risks associated with this compound. It is important to follow proper procedures for handling, storing, and disposing of 2-Amino-2-phenylacetic acid to ensure the safety of laboratory personnel and the surrounding environment.
🔬 Potential Research Directions
One potential research direction for 2-Amino-2-phenylacetic acid is its potential use as a building block in the synthesis of novel pharmaceutical compounds. Understanding its chemical reactivity and ability to form various derivatives could lead to the development of new therapeutics with improved efficacy and reduced side effects.
Another promising area of research is exploring the biological activity of 2-Amino-2-phenylacetic acid and its derivatives. Investigating its interactions with biological targets, such as enzymes or receptors, could provide insights into its potential pharmacological properties. Furthermore, studying its effects on cellular processes could uncover new therapeutic applications for this compound.
🧪 Related Compounds
Compounds that are structurally similar to 2-Amino-2-phenylacetic acid can include those with a similar skeleton but differing functional groups. For example, a compound with the same 2-phenylacetic acid skeleton but a hydroxyl group instead of an amino group would be 2-Hydroxy-2-phenylacetic acid. This modification changes the compound’s properties and potential biological activities while maintaining the core structure.
Similarly, replacing the amino group with a nitro group would result in 2-Nitro-2-phenylacetic acid. This alteration introduces a more polar group, potentially impacting the compound’s solubility and reactivity. These subtle structural changes can have significant implications for the compound’s behavior and applications in various fields such as medicine or material science.
Furthermore, a substitution of the phenyl ring with another aromatic group could lead to compounds like 2-Amino-2-(4-methoxyphenyl)acetic acid. This modification alters the compound’s aromaticity and electronic properties, potentially influencing its interactions with other molecules or biological systems. By exploring these structural variations, researchers can gain insights into structure-activity relationships and develop new compounds with tailored functionalities.