2-Amino-2-methyl-1,3-propanediol is a compound that plays a crucial role in various industries, including pharmaceuticals, cosmetics, and food processing. In everyday life, this chemical is commonly used as a buffering agent in skincare products, as well as a stabilizer in pharmaceutical formulations. Its ability to adjust the pH of these products makes it a key ingredient in ensuring their efficacy and safety for consumers. Additionally, 2-Amino-2-methyl-1,3-propanediol is utilized in the production of certain types of medications and can be found in various over-the-counter drugs. As such, this compound holds significant importance in maintaining quality standards and meeting regulatory requirements in everyday consumer goods.
Table of Contents:
- 💡 Commercial Applications
- ⚗️ Chemical & Physical Properties
- 🏭 Production & Procurement
- ⚠️ Safety Considerations
- 🔬 Potential Research Directions
- 🧪 Related Compounds
💡 Commercial Applications
2-Amino-2-methyl-1,3-propanediol, also known as AMPD, has several commercial and industrial applications. It is commonly used as a pH adjuster in various cosmetic and personal care products such as hair dyes, hair conditioners, and cleansers. AMPD is also used as a buffer and neutralizing agent in pharmaceuticals, paints, and industrial chemicals.
In the pharmaceutical industry, 2-Amino-2-methyl-1,3-propanediol is used as an intermediate in the synthesis of various drugs and medications. It is a key ingredient in the production of certain antihistamines, bronchodilators, and anti-inflammatory drugs. AMPD is also utilized in the manufacturing of diagnostic reagents and contrast media for medical imaging procedures.
Additionally, 2-Amino-2-methyl-1,3-propanediol plays a crucial role in the production of agricultural chemicals and pesticides. It is used as a solvent, stabilizer, or reaction catalyst in the formulation of herbicides, insecticides, and fungicides. AMPD’s ability to adjust pH levels and act as a buffer makes it a versatile compound with a wide range of applications in various industries.
⚗️ Chemical & Physical Properties
2-Amino-2-methyl-1,3-propanediol, commonly known as AMPD, is a colorless crystalline solid with a slight odor. It is a hygroscopic compound, meaning it readily absorbs moisture from the air, which can affect its appearance over time.
With a molar mass of approximately 103.14 g/mol and a density of around 1.05 g/cm3, 2-Amino-2-methyl-1,3-propanediol is heavier and more dense than common household items such as water (molar mass of 18 g/mol and density of 1 g/cm3). Its molecular weight and density make it a relatively compact and heavy compound.
The melting point of 2-Amino-2-methyl-1,3-propanediol is around 70-75°C, while its boiling point is approximately 250°C. These values are higher than those of many common household items, such as water (melting point of 0°C and boiling point of 100°C), indicating that AMPD is more thermally stable under normal conditions.
2-Amino-2-methyl-1,3-propanediol is highly soluble in water, forming a clear, colorless solution. It is relatively viscous, with a thick consistency compared to substances like alcohol or vinegar. This high solubility in water and viscosity make it suitable for various applications in industries such as pharmaceuticals and cosmetics.
🏭 Production & Procurement
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2-Amino-2-methyl-1,3-propanediol, also known as AMPD, is typically produced through the reaction of acetone with ammonia and formaldehyde. This reaction results in the formation of the desired compound, which can then undergo further purification processes to obtain the final product. The production of AMPD requires careful control of reaction conditions to ensure high yield and purity.
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Once 2-Amino-2-methyl-1,3-propanediol has been successfully produced, it can be procured in various forms such as liquid or solid. The compound is commonly transported in sealed containers to prevent contamination or degradation during transit. Depending on the quantity required, 2-Amino-2-methyl-1,3-propanediol can be shipped internationally or domestically using standard shipping methods.
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Procurement of 2-Amino-2-methyl-1,3-propanediol typically involves contacting specialized chemical suppliers or manufacturers. These suppliers can provide the compound in different quantities based on the needs of the customer. It is essential to verify the quality and purity of the product before making a purchase to ensure its suitability for specific applications.
⚠️ Safety Considerations
Safety considerations for 2-Amino-2-methyl-1,3-propanediol must be carefully observed due to its potential hazards. This compound should be handled with caution to avoid skin and eye contact, ingestion, or inhalation. It is advisable to wear appropriate personal protective equipment, such as gloves and safety glasses, when working with 2-Amino-2-methyl-1,3-propanediol to minimize the risk of exposure.
The pharmacology of 2-Amino-2-methyl-1,3-propanediol involves its role as a pH buffer in various applications. This compound is commonly used in the pharmaceutical industry as an ingredient in formulations, where it helps to maintain the stability and efficacy of certain drugs. Additionally, 2-Amino-2-methyl-1,3-propanediol is utilized in the production of cosmetics and personal care products, where it serves as a neutralizing agent to adjust the pH of formulations.
Hazard statements for 2-Amino-2-methyl-1,3-propanediol should be carefully considered to ensure safe handling and storage practices. This compound is harmful if swallowed and may cause skin and eye irritation upon contact. Prolonged or repeated exposure to 2-Amino-2-methyl-1,3-propanediol may result in respiratory irritation. It is important to keep this compound away from heat sources, open flames, and incompatible materials to prevent potential hazards.
Precautionary statements for 2-Amino-2-methyl-1,3-propanediol should be followed as part of a comprehensive risk management strategy. It is recommended to store this compound in a cool, dry, well-ventilated area away from oxidizing agents and sources of ignition. When handling 2-Amino-2-methyl-1,3-propanediol, it is crucial to use proper ventilation to minimize the risk of inhalation exposure. In case of accidental exposure, first aid measures should be promptly administered, and medical attention sought if necessary.
🔬 Potential Research Directions
One potential research direction for 2-Amino-2-methyl-1,3-propanediol is its role as a versatile intermediate in organic synthesis. Its unique structure allows for various functionalizations, making it a valuable building block for the synthesis of complex molecules.
Another area of interest is the investigation of the pharmacological properties of 2-Amino-2-methyl-1,3-propanediol. Studies could focus on its potential as a drug candidate, exploring its interactions with biological targets and its pharmacokinetic profile. This research could lead to the development of novel pharmaceuticals with improved efficacy and safety profiles.
Furthermore, the biodegradability and environmental impact of 2-Amino-2-methyl-1,3-propanediol could be explored in environmental science research. Understanding its fate in the environment and its potential to accumulate in ecosystems is essential for assessing its overall impact on the environment. This information could inform regulatory decisions regarding its use in various industries.
🧪 Related Compounds
One similar compound to 2-Amino-2-methyl-1,3-propanediol is 1,3-Diamino-2-propanol. This compound shares a similar molecular structure with 2-Amino-2-methyl-1,3-propanediol, as it contains two amino groups and a hydroxy group attached to a propanediol backbone. 1,3-Diamino-2-propanol is often used in pharmaceutical and cosmetic products due to its properties and versatility.
Another comparable compound is N-Methylethanolamine, which is structurally related to 2-Amino-2-methyl-1,3-propanediol. N-Methylethanolamine consists of an amino group, a hydroxyl group, and a methyl group attached to an ethanolamine backbone. This compound is commonly utilized as a corrosion inhibitor in various industrial processes and as a component in paint strippers.
An additional analogous compound is 2-Amino-2-ethyl-1,3-propanediol. This compound closely resembles 2-Amino-2-methyl-1,3-propanediol in structure, with the only difference being the substitution of a methyl group with an ethyl group. 2-Amino-2-ethyl-1,3-propanediol is utilized in a variety of applications such as pharmaceutical formulations, emulsifiers, and corrosion inhibitors due to its chemical properties.
