2-Amino-1-phenyl-1-propanol is a compound that has a wide range of applications in everyday life. It is commonly used in the production of pharmaceutical drugs, particularly as a key intermediate in the synthesis of various medications. Additionally, it is utilized in the manufacturing of certain fragrances and as a chemical reagent in various laboratory procedures. Its versatility and importance in these industries make 2-Amino-1-phenyl-1-propanol a significant compound in our daily lives, albeit often unnoticed by the general public.
Table of Contents:
- 💡 Commercial Applications
- ⚗️ Chemical & Physical Properties
- 🏭 Production & Procurement
- ⚠️ Safety Considerations
- 🔬 Potential Research Directions
- 🧪 Related Compounds
💡 Commercial Applications
In commercial and industrial applications, 2-Amino-1-phenyl-1-propanol is commonly used as a building block in the synthesis of various pharmaceutical chemicals and agrochemicals. It is also utilized in the production of specialty chemicals such as corrosion inhibitors and surfactants. Additionally, this compound is employed as a chiral auxiliary in asymmetric synthesis processes.
2-Amino-1-phenyl-1-propanol is also utilized in the pharmaceutical industry for the synthesis of various drugs and medications. It is particularly valuable in the preparation of beta-blockers, which are used to treat cardiovascular conditions such as hypertension and angina. Furthermore, this compound is employed in the synthesis of antidepressants and antiarrhythmic agents, demonstrating its versatility in pharmaceutical applications.
⚗️ Chemical & Physical Properties
2-Amino-1-phenyl-1-propanol appears as a white crystalline solid with a faint odor. It is commonly used in the pharmaceutical industry as a precursor to various drugs.
The molar mass of 2-Amino-1-phenyl-1-propanol is approximately 149.21 g/mol, with a density of about 1.02 g/cm³. This places it in the range of molar mass and density of common food items such as table sugar and table salt.
2-Amino-1-phenyl-1-propanol has a melting point of around 55-60°C and a boiling point of approximately 213-215°C. These values are significantly higher than those of common food items such as butter and chocolate, which melt at lower temperatures.
2-Amino-1-phenyl-1-propanol is sparingly soluble in water and exhibits low viscosity. This sets it apart from common food items like sugar and salt, which are highly soluble in water and have varying viscosities.
🏭 Production & Procurement
2-Amino-1-phenyl-1-propanol, also known as alpha-Methylbenzylamine, is typically produced through a process involving the reaction of benzylamine with sodium nitrite followed by reduction with iron powder in the presence of acetic acid. This yields 2-Amino-1-phenyl-1-propanol as the final product, which can then be further purified through various methods such as recrystallization or distillation.
The procurement of 2-Amino-1-phenyl-1-propanol involves sourcing the necessary chemicals and equipment for the synthesis process. These can be obtained through chemical suppliers or specialized laboratories that cater to the needs of chemical research and production. Once the compound is synthesized, it can be transported in securely sealed containers to its intended destination, following proper safety regulations and guidelines for handling hazardous materials.
Overall, the production and procurement of 2-Amino-1-phenyl-1-propanol require careful attention to detail and adherence to safety protocols. This compound is used in various industries such as pharmaceuticals, dyes, and chemical synthesis, making it essential to ensure the quality and purity of the product throughout its production and transportation process.
⚠️ Safety Considerations
Safety considerations for 2-Amino-1-phenyl-1-propanol should include proper storage and handling procedures to minimize the risk of exposure. This compound should be stored in a cool, dry place away from sources of heat or ignition. Personal protective equipment such as gloves and safety goggles should be worn when handling 2-Amino-1-phenyl-1-propanol to prevent skin contact or inhalation of fumes.
Hazard statements for 2-Amino-1-phenyl-1-propanol include its classification as a hazardous substance that may cause skin irritation and serious eye damage. This compound may also be harmful if swallowed or inhaled, and can cause respiratory irritation. Long-term exposure to 2-Amino-1-phenyl-1-propanol may result in adverse health effects, so proper precautions should be taken to minimize exposure.
Precautionary statements for 2-Amino-1-phenyl-1-propanol should emphasize the importance of avoiding direct contact with the substance and ensuring adequate ventilation during use. In case of skin contact, affected areas should be rinsed thoroughly with water and medical attention sought if irritation persists. If 2-Amino-1-phenyl-1-propanol is ingested or inhaled, medical advice should be sought immediately, and the individual should be removed from the contaminated area to receive proper treatment. Personal protective equipment should be worn at all times when handling this compound to reduce the risk of exposure.
🔬 Potential Research Directions
Potential research directions for 2-Amino-1-phenyl-1-propanol (2-APP) could include exploring its pharmacological properties and potential therapeutic applications. Studies may focus on investigating its interactions with specific receptors or enzymes, as well as its effects on various physiological functions.
Another possible research direction for 2-APP could involve examining its synthesis methods and chemical reactions to develop new analogs with improved pharmacokinetic or pharmacodynamic profiles. This could lead to the development of novel drug candidates with enhanced efficacy or reduced side effects, potentially expanding the therapeutic options available to patients.
Furthermore, research on the toxicological profile of 2-APP and its metabolites could provide valuable insights into its safety and potential risks. Studies may aim to determine the potential adverse effects associated with its use, as well as the mechanisms underlying its toxicity in different biological systems. This information could help inform regulatory decisions and guide further research on the compound’s safety and efficacy.
🧪 Related Compounds
One similar compound to 2-Amino-1-phenyl-1-propanol based upon molecular structure is 2-Amino-1-phenylpropan-1-ol. This compound differs from the original by having one fewer carbon atom in the alkyl chain. This alteration affects the compound’s physicochemical properties and may result in different biological activities.
Another compound similar to 2-Amino-1-phenyl-1-propanol is N,N-dimethyl-2-amino-1-phenylpropan-1-ol. In this compound, one of the hydrogen atoms on the amino group has been substituted with a methyl group. This modification can lead to changes in the compound’s solubility, stability, and pharmacological effects.
One more compound akin to 2-Amino-1-phenyl-1-propanol is 2-Amino-1-(4-methylphenyl)-1-propanol. In this molecule, the phenyl group is substituted with a 4-methylphenyl group, resulting in a change in the compound’s stereochemistry. This alteration may affect the compound’s interactions with biological targets and its overall pharmacological profile.
