2-(6-Hydroxy-3-oxo-3H-xanthen-9-yl)benzoic acid, also known as Fluorescein, is a compound commonly used in everyday life for a variety of applications. It is widely utilized as a fluorescent dye in industries such as textiles, plastics, and cosmetics. Additionally, it plays a crucial role in medical diagnostics, specifically in the field of ophthalmology for eye examinations and determining corneal damage. Due to its bright fluorescent properties, Fluorescein is also used in the food industry for tracing leaks during the packaging process. Overall, this compound has practical applications that impact our daily lives in various ways.
Table of Contents:
- 💡 Commercial Applications
- ⚗️ Chemical & Physical Properties
- 🏭 Production & Procurement
- ⚠️ Safety Considerations
- 🔬 Potential Research Directions
- 🧪 Related Compounds
💡 Commercial Applications
The compound 2-(6-Hydroxy-3-oxo-3H-xanthen-9-yl)benzoic acid, also known as Fluorescein, has various commercial and industrial applications. It is commonly used as a fluorescent dye in industries such as textiles, cosmetics, and food coloring. Fluorescein is also utilized in forensics, where it is used to detect latent blood stains on various surfaces. Additionally, it is used in the medical field as a contrast agent for imaging studies.
In the realm of drug and medication applications, Fluorescein has found use in ophthalmology as a diagnostic tool for various eye diseases and conditions. It is commonly used in fluorescein angiography, a diagnostic procedure where the dye is injected into a patient’s bloodstream to highlight blood vessels in the eye. This enables doctors to identify and monitor conditions like diabetic retinopathy, macular degeneration, and vascular occlusions. Overall, Fluorescein’s unique fluorescent properties make it invaluable in both commercial and medical settings.
⚗️ Chemical & Physical Properties
2-(6-Hydroxy-3-oxo-3H-xanthen-9-yl)benzoic acid appears as a white crystalline solid with no distinct odor. It is typically found in a powdered form, which can easily dissolve in various solvents.
The molar mass of 2-(6-Hydroxy-3-oxo-3H-xanthen-9-yl)benzoic acid is approximately 318.29 g/mol, with a density of around 1.37 g/cm³. Compared to common food items such as sugar (molar mass ≈ 342.3 g/mol, density ≈ 1.59 g/cm³) and salt (molar mass ≈ 58.44 g/mol, density ≈ 2.165 g/cm³), it is lighter and less dense.
The melting point of 2-(6-Hydroxy-3-oxo-3H-xanthen-9-yl)benzoic acid is around 280-285°C, while the boiling point is approximately 615-620°C. In comparison, common food items like butter (melting point ≈ 32-35°C, boiling point ≈ 150°C) and chocolate (melting point ≈ 34-38°C, boiling point ≈ 116-118°C) have significantly lower melting and boiling points.
2-(6-Hydroxy-3-oxo-3H-xanthen-9-yl)benzoic acid has low solubility in water but is highly soluble in organic solvents, which results in a low viscosity. This is in contrast to common food items like sugar and salt, which are highly soluble in water and have higher viscosities when dissolved.
🏭 Production & Procurement
Paragraph 1: The production of 2-(6-Hydroxy-3-oxo-3H-xanthen-9-yl)benzoic acid involves the synthesis of xanthenone followed by its reaction with benzoic acid. Xanthenone is typically prepared through the reaction of salicylic aldehyde with dimedone in the presence of acidic catalysts. This intermediate is then reacted with benzoic acid in the presence of suitable reagents to yield the desired product.
Paragraph 2: 2-(6-Hydroxy-3-oxo-3H-xanthen-9-yl)benzoic acid can be procured from chemical suppliers specializing in rare organic compounds. The compound is typically transported in sealed containers to prevent degradation due to exposure to light or moisture. It is important to handle and store this compound in a dry, cool, and dark environment to maintain its stability.
⚠️ Safety Considerations
Safety considerations for 2-(6-Hydroxy-3-oxo-3H-xanthen-9-yl)benzoic acid must be taken into account when handling this chemical compound. It is important to wear appropriate personal protective equipment such as gloves, goggles, and lab coat to prevent skin contact and inhalation of vapors. Additionally, this compound should be used in a well-ventilated area to minimize exposure and the risk of adverse health effects.
Hazard statements for 2-(6-Hydroxy-3-oxo-3H-xanthen-9-yl)benzoic acid include: may be harmful if swallowed, may cause skin and eye irritation, and may cause respiratory irritation. It is important to handle this compound with caution and follow proper safety protocols to avoid potential risks associated with its use.
Precautionary statements for 2-(6-Hydroxy-3-oxo-3H-xanthen-9-yl)benzoic acid include: wear protective gloves/eye protection/face protection, do not eat, drink or smoke when using this product, and wash hands thoroughly after handling. It is essential to adhere to these precautionary measures to ensure safe handling and minimize the risk of exposure to this chemical compound.
🔬 Potential Research Directions
Potential research directions for 2-(6-Hydroxy-3-oxo-3H-xanthen-9-yl)benzoic acid may include investigating its biological activities, such as its potential as an antioxidant or anti-inflammatory agent. Researchers may also explore its potential use in drug development for the treatment of various diseases.
Additionally, further studies could focus on understanding the chemical properties and synthesis methods of 2-(6-Hydroxy-3-oxo-3H-xanthen-9-yl)benzoic acid, in order to optimize its production and improve its stability. This could lead to the development of more efficient and cost-effective methods for producing this compound.
Moreover, research efforts could be directed towards elucidating the mechanism of action of 2-(6-Hydroxy-3-oxo-3H-xanthen-9-yl)benzoic acid, in order to better understand how it interacts with biological systems and exerts its effects. This knowledge could potentially pave the way for the development of novel therapeutic interventions based on this compound.
🧪 Related Compounds
One similar compound to 2-(6-Hydroxy-3-oxo-3H-xanthen-9-yl)benzoic acid is 1-(6-Hydroxy-3-oxo-3H-xanthen-9-yl)benzoic acid. In this compound, the hydroxyl group is attached to the first carbon of the xanthene ring, rather than the second carbon as in the original compound. This subtle change in attachment can lead to variations in biological activity and chemical reactivity.
Another similar compound is 2-(6-Methoxy-3-oxo-3H-xanthen-9-yl)benzoic acid. Here, the hydroxyl group in the original compound is replaced with a methoxy group, altering the polarity and hydrogen bonding capabilities of the molecule. This substitution can influence the compound’s solubility, stability, and interaction with biological targets.
A third similar compound is 2-(6-Hydroxy-3-oxo-3H-xanthen-9-yl)phenylacetic acid. In this variant, the benzoic acid moiety of the original compound is replaced with a phenylacetic acid group. This structural modification can impact the compound’s binding affinity, metabolism, and overall biological effects. Understanding the structure-activity relationships of these related compounds can provide valuable insights for drug design and development.
