2-(((2-Ethylhexyl)oxy)carbonyl)benzoic acid, more commonly known as Octocrylene, is a key ingredient in many sunscreens and cosmetic products. Its role as a UV filter helps protect the skin from harmful effects of sun exposure, including premature aging and skin cancer. Therefore, this compound plays a crucial role in everyday life by aiding individuals in maintaining healthy skin while enjoying outdoor activities.
Table of Contents:
- 💡 Commercial Applications
- ⚗️ Chemical & Physical Properties
- 🏭 Production & Procurement
- ⚠️ Safety Considerations
- 🔬 Potential Research Directions
- 🧪 Related Compounds
💡 Commercial Applications
Despite its complex chemical name, 2-(((2-Ethylhexyl)oxy)carbonyl)benzoic acid, also known as Octocrylene, is commonly used in commercial and industrial applications. This compound is utilized as a UV filter in sunscreen products due to its ability to absorb UVB radiation and stabilize other UV filters. Additionally, Octocrylene is often added to cosmetic formulations to increase SPF levels and provide protection against sun damage.
In the realm of drug and medication applications, 2-(((2-Ethylhexyl)oxy)carbonyl)benzoic acid is rarely used. However, some topical medications may contain Octocrylene for its ability to enhance the stability of other active ingredients. It is important for pharmaceutical manufacturers to consider the potential sensitizing effects of this compound when formulating medications, as some individuals may experience allergic reactions upon prolonged exposure. Further research is needed to explore the medicinal properties and limitations of Octocrylene in pharmaceutical products.
⚗️ Chemical & Physical Properties
2-(((2-Ethylhexyl)oxy)carbonyl)benzoic acid is a white, odorless crystalline solid at room temperature. It possesses no distinct odor, making it suitable for various applications in the chemical industry.
The molar mass of 2-(((2-Ethylhexyl)oxy)carbonyl)benzoic acid is 316.42 g/mol, with a density of approximately 1.05 g/cm³. Comparatively, common food items like sugar (sucrose) have a molar mass of 342.3 g/mol and a density of 1.59 g/cm³.
2-(((2-Ethylhexyl)oxy)carbonyl)benzoic acid has a melting point of around 121-123°C and a boiling point of approximately 380°C. These values differ significantly from common food items like butter (melting point of 32-35°C) and water (boiling point of 100°C).
This compound is sparingly soluble in water and exhibits low viscosity. In contrast, common food items such as salt are highly soluble in water, while honey demonstrates higher viscosity levels.
🏭 Production & Procurement
2-(((2-Ethylhexyl)oxy)carbonyl)benzoic acid, commonly known as octinoxate, is produced through a multistep synthesis process involving the esterification of salicylic acid with 2-ethylhexanol. This reaction is typically catalyzed by an acid, such as sulfuric acid, to form the desired product.
Once the 2-(((2-Ethylhexyl)oxy)carbonyl)benzoic acid is synthesized, it can be procured from chemical manufacturers or suppliers specializing in cosmetic and pharmaceutical ingredients. The substance is typically transported in sealed containers, such as drums or bottles, to ensure purity and prevent any contamination during transit.
Organizations that require 2-(((2-Ethylhexyl)oxy)carbonyl)benzoic acid for research or production purposes can place orders with approved suppliers, who will arrange for the safe and efficient delivery of the compound. It is essential to follow proper handling and storage protocols to maintain the integrity and quality of the product.
⚠️ Safety Considerations
Safety considerations for 2-(((2-Ethylhexyl)oxy)carbonyl)benzoic acid must be taken seriously due to its potential hazards. It is important to handle this compound with care, wearing appropriate personal protective equipment such as gloves, goggles, and a lab coat. Additionally, it should only be used in a well-ventilated area to minimize the risk of inhalation exposure. Proper storage of 2-(((2-Ethylhexyl)oxy)carbonyl)benzoic acid is crucial to prevent accidental spills or leaks, as it can be harmful if it comes into contact with skin or eyes.
The hazard statements for 2-(((2-Ethylhexyl)oxy)carbonyl)benzoic acid include “Causes skin irritation” and “Causes serious eye irritation.” These statements indicate that direct contact with this compound can lead to irritation and potential harm. It is crucial to take appropriate precautions when handling 2-(((2-Ethylhexyl)oxy)carbonyl)benzoic acid to avoid any adverse effects on the skin or eyes.
Precautionary statements for 2-(((2-Ethylhexyl)oxy)carbonyl)benzoic acid include “Wear protective gloves/protective clothing/eye protection/face protection” and “Wash thoroughly after handling.” These statements emphasize the importance of using proper protective equipment when working with this compound. It is also essential to thoroughly wash any exposed skin after handling 2-(((2-Ethylhexyl)oxy)carbonyl)benzoic acid to minimize the risk of irritation or other adverse effects.
🔬 Potential Research Directions
Potential research directions for 2-(((2-Ethylhexyl)oxy)carbonyl)benzoic acid may include its role as a UV filter in sunscreens and other cosmetic formulations. This compound has the potential to enhance the photoprotective properties of sunscreens, thereby contributing to the prevention of UV-induced skin damage.
Another possible research direction could explore the environmental impact of 2-(((2-Ethylhexyl)oxy)carbonyl)benzoic acid, particularly its potential for bioaccumulation in aquatic organisms. Understanding the fate and transport of this compound in the environment is crucial for assessing its potential risks to ecosystems and human health.
Furthermore, investigations into the synthesis and stability of 2-(((2-Ethylhexyl)oxy)carbonyl)benzoic acid derivatives could lead to the development of novel sunscreen formulations with improved efficacy and safety profiles. These studies may provide valuable insights into the structure-activity relationships of this compound and its analogs, paving the way for the design of next-generation UV filters.
🧪 Related Compounds
One similar compound to 2-(((2-Ethylhexyl)oxy)carbonyl)benzoic acid is 2-(((2-Methylbutyl)oxy)carbonyl)benzoic acid. In this compound, the ethyl group in the 2-Ethylhexyl chain is replaced with a methyl group. This substitution results in a slightly different molecular structure while retaining the overall ester functionality.
Another analogous compound is 2-(((2-Propyl)oxy)carbonyl)benzoic acid. In this compound, the ethyl group in the 2-Ethylhexyl chain is replaced with a propyl group. This modification alters the size and shape of the alkyl chain attached to the carboxylic acid group, leading to different chemical properties compared to 2-(((2-Ethylhexyl)oxy)carbonyl)benzoic acid.
Additionally, 2-(((2-Butyl)oxy)carbonyl)benzoic acid is a compound similar to 2-(((2-Ethylhexyl)oxy)carbonyl)benzoic acid. Here, the ethyl group is substituted with a butyl group in the alkyl chain. This alteration affects the hydrophobicity and overall structure of the molecule, potentially influencing its biological or chemical properties.
