1H-Benzimidazol-2-yl(phenyl)methanol is a chemical compound that holds significance in various industries ranging from pharmaceuticals to materials science. This compound has been studied for its potential applications in drug development, particularly in the treatment of various diseases. Additionally, its unique chemical structure makes it a promising candidate for creating advanced materials with specific properties. In everyday life, 1H-Benzimidazol-2-yl(phenyl)methanol has the potential to impact the development of new medicines and innovative materials that could enhance various aspects of our daily lives.
Table of Contents:
- 💡 Commercial Applications
- ⚗️ Chemical & Physical Properties
- 🏭 Production & Procurement
- ⚠️ Safety Considerations
- 🔬 Potential Research Directions
- 🧪 Related Compounds
💡 Commercial Applications
1H-Benzimidazol-2-yl(phenyl)methanol, a compound known for its versatility, finds several commercial and industrial applications. It is often utilized in the production of pharmaceuticals, pigments, and dyes, owing to its unique chemical properties. Additionally, this compound serves as a key building block for the synthesis of various organic compounds used in the manufacturing sector.
In the realm of drug and medication applications, 1H-Benzimidazol-2-yl(phenyl)methanol plays a crucial role. Its ability to interact with biological systems makes it a valuable component in the pharmaceutical industry. This compound is commonly used in the development of antimicrobial agents, antiviral drugs, and other therapeutic agents targeted at combating diseases and infections.
Furthermore, the presence of 1H-Benzimidazol-2-yl(phenyl)methanol in drug formulations has been shown to enhance their efficacy and bioavailability. Its molecular structure allows for strategic modifications that can improve drug targeting, absorption, and overall therapeutic outcomes. As such, this compound continues to be a valuable asset in the development of novel medications and treatments.
⚗️ Chemical & Physical Properties
1H-Benzimidazol-2-yl(phenyl)methanol appears as a white crystalline solid with no distinct odor. Its physical appearance is reminiscent of powdered sugar or sea salt, with a powdery texture.
The molar mass of 1H-Benzimidazol-2-yl(phenyl)methanol is approximately 232.26 g/mol, and its density is around 1.28 g/cm3. In comparison, common food items such as table sugar have a molar mass of 342.3 g/mol and a density of 1.59 g/cm3, indicating that 1H-Benzimidazol-2-yl(phenyl)methanol is lighter and less dense.
1H-Benzimidazol-2-yl(phenyl)methanol has a melting point of around 158-160°C and a boiling point of approximately 370°C. In contrast, common food items like butter have a melting point of 30-35°C and a boiling point above 200°C, illustrating that 1H-Benzimidazol-2-yl(phenyl)methanol has higher melting and boiling points.
1H-Benzimidazol-2-yl(phenyl)methanol is sparingly soluble in water and exhibits a low viscosity. Compared to common food items like salt, which dissolves readily in water, and honey, which is highly viscous, 1H-Benzimidazol-2-yl(phenyl)methanol has different solubility characteristics and viscosity levels.
🏭 Production & Procurement
1H-Benzimidazol-2-yl(phenyl)methanol is typically produced through a multistep synthesis process involving the condensation of o-phenylenediamine with ortho-formylbenzoic acid, followed by reduction of the resulting imine intermediate.
Once synthesized, 1H-Benzimidazol-2-yl(phenyl)methanol can be procured from chemical suppliers specializing in fine chemicals. The compound is usually transported in sealed containers to prevent contamination or degradation during transit.
When procuring 1H-Benzimidazol-2-yl(phenyl)methanol, it is essential to ensure that the compound meets the required purity standards for its intended application. It is advisable to consult with chemical suppliers regarding handling and storage guidelines to maintain the compound’s stability.
⚠️ Safety Considerations
Safety considerations for 1H-Benzimidazol-2-yl(phenyl)methanol include the need for proper storage and handling to prevent accidental exposure. This compound should be stored in a cool, dry place away from sources of ignition and incompatible chemicals. Personal protective equipment such as gloves, safety goggles, and a lab coat should be worn when working with 1H-Benzimidazol-2-yl(phenyl)methanol to minimize the risk of skin and eye irritation.
In addition, proper ventilation is necessary when handling this compound to prevent inhalation of vapors. It is important to work with 1H-Benzimidazol-2-yl(phenyl)methanol in a fume hood or well-ventilated area to reduce the risk of respiratory irritation or other adverse health effects. Spills should be cleaned up promptly and in accordance with appropriate safety procedures to prevent contamination of the work area.
The hazard statements for 1H-Benzimidazol-2-yl(phenyl)methanol include “Causes skin irritation” and “May cause respiratory irritation.” These statements indicate that exposure to this compound can result in irritation to the skin and respiratory system. It is important to take precautions to minimize contact with 1H-Benzimidazol-2-yl(phenyl)methanol and to handle it in a well-ventilated area to reduce the risk of adverse health effects.
Precautionary statements for 1H-Benzimidazol-2-yl(phenyl)methanol include wearing protective gloves, eye protection, and face protection. It is also recommended to work with this compound in a well-ventilated area and to avoid breathing in vapors or mist. In case of skin contact, the affected area should be washed with plenty of soap and water, and in case of respiratory irritation, fresh air should be sought immediately. Proper disposal methods for 1H-Benzimidazol-2-yl(phenyl)methanol should also be followed to prevent environmental contamination.
🔬 Potential Research Directions
One potential research direction for 1H-Benzimidazol-2-yl(phenyl)methanol could involve its pharmacological properties, such as studying its potential as a drug candidate for certain diseases or as a building block for new drug design. Researchers may also investigate its potential biological activities, such as its interactions with specific enzymes or receptors in biological systems.
Another area of study could focus on the synthesis and modification of 1H-Benzimidazol-2-yl(phenyl)methanol to explore its chemical reactivity and potential applications in organic synthesis. Researchers could explore different synthetic routes to prepare this compound and develop new methods for its transformation into structurally related compounds with diverse properties.
Furthermore, the investigation of the structural characteristics of 1H-Benzimidazol-2-yl(phenyl)methanol through techniques such as X-ray crystallography or computational modeling may provide valuable insights into its molecular conformation, intermolecular interactions, and potential binding sites for further biological or chemical studies. Such structural studies could aid in the rational design of derivatives with improved activity or specificity for specific targets.
🧪 Related Compounds
One similar compound to 1H-Benzimidazol-2-yl(phenyl)methanol is 1H-Benzimidazole-2-yl(4-methylphenyl)methanol. This compound has the same benzimidazole core structure with a phenyl group attached to the nitrogen atom. However, in this case, the phenyl group is substituted with a methyl group in the para position. This substitution can affect the compound’s physical and chemical properties, such as solubility and reactivity.
Another similar compound is 1H-Benzimidazole-2-yl(2-methoxyphenyl)methanol. Like the previous compound, this molecule features a benzimidazole core structure with a phenyl group attached to the nitrogen atom. In this case, the phenyl group is substituted with a methoxy group in the ortho position. The presence of the methoxy group can influence the compound’s biological activity and interactions with other molecules.
A third related compound is 1H-Benzimidazole-2-yl(3-chlorophenyl)methanol. This compound shares the same benzimidazole core structure with a phenyl group attached to the nitrogen atom. However, in this case, the phenyl group is substituted with a chlorine atom in the meta position. The presence of the chlorine atom can impact the compound’s stability and potential interactions with biological targets.
