1,6-di-O-phosphono-D-fructose, a compound with potential applications in the field of pharmaceuticals and agriculture, is relevant to everyday life as it offers promise in the development of new drugs and enhancers for crop yield. The compound’s unique properties make it a subject of interest for researchers seeking to address health and food security challenges. Its study and potential utilization could lead to advancements that impact society at large.
Table of Contents:
- 💡 Commercial Applications
- ⚗️ Chemical & Physical Properties
- 🏭 Production & Procurement
- ⚠️ Safety Considerations
- 🔬 Potential Research Directions
- 🧪 Related Compounds
💡 Commercial Applications
1,6-di-O-phosphono-D-fructose, also known as DPMF, is primarily used in commercial and industrial applications due to its ability to chelate metal ions. This compound is commonly employed as a metal chelating agent in industries such as food processing, textile manufacturing, and water treatment. Its strong chelation properties make it an effective ingredient in various products aimed at preventing metal ion contamination and corrosion.
In the field of drug development and medication, 1,6-di-O-phosphono-D-fructose has shown promise as a potential therapeutic agent for conditions related to metal ion imbalance. Studies have shown that this compound has the ability to bind to excess metal ions in the body, potentially offering a new avenue for the treatment of metal ion-related disorders such as Wilson’s disease. Research is ongoing to explore the potential medicinal applications of DPMF and its chelating properties in the context of human health.
Overall, the commercial and industrial applications of 1,6-di-O-phosphono-D-fructose are primarily centered around its metal chelating properties, while its potential medicinal applications involve the regulation of metal ion levels in the body. As research continues to uncover the full range of applications for this compound, it is poised to play an important role in various fields, from industrial processes to medical treatments.
⚗️ Chemical & Physical Properties
1,6-di-O-phosphono-D-fructose is a white crystalline powder with no distinctive odor. It is commonly used as a food additive due to its sweetness and stability.
The molar mass of 1,6-di-O-phosphono-D-fructose is approximately 390.1 g/mol, with a density of about 1.7 g/cm³. Compared to common food items like sugar (molar mass: 342.3 g/mol, density: 1.59 g/cm³), 1,6-di-O-phosphono-D-fructose has a higher molar mass and density.
1,6-di-O-phosphono-D-fructose has a melting point of around 195-198°C and a boiling point of approximately 638°C. These values are higher than those of common food items like sucrose (melting point: 186°C, boiling point: 376°C).
1,6-di-O-phosphono-D-fructose is highly soluble in water and has a low viscosity. Compared to common food items like salt (solubility: highly soluble, viscosity: low) and honey (solubility: slightly soluble, viscosity: high), 1,6-di-O-phosphono-D-fructose exhibits similar solubility but lower viscosity.
🏭 Production & Procurement
1,6-di-O-phosphono-D-fructose is produced through a multistep synthesis process involving the condensation of D-fructose with phosphorus oxychloride and subsequent reaction with sodium trimethylsilyl-phosphite. This process results in the formation of a phosphonate ester intermediate, which is then selectively deprotected to yield the final product.
1,6-di-O-phosphono-D-fructose can be procured from specialized chemical suppliers who offer this compound for research purposes. The compound is typically supplied as a white crystalline powder or as a solution in organic solvents. Due to its stability, 1,6-di-O-phosphono-D-fructose can be safely transported under ambient conditions without the need for special precautions.
Upon procurement, 1,6-di-O-phosphono-D-fructose should be handled and stored in a dry, cool, and well-ventilated area to prevent decomposition or degradation. Proper labeling and documentation of the compound are essential to ensure traceability and regulatory compliance. When transporting this compound, standard chemical safety practices should be followed to minimize the risk of exposure or accidental spillage.
⚠️ Safety Considerations
Safety considerations for 1,6-di-O-phosphono-D-fructose should be taken seriously due to its potential hazards. This compound may cause irritation to the eyes, skin, and respiratory system upon contact. It is important to handle it with care, using appropriate personal protective equipment such as gloves and goggles to prevent any accidental exposure. Additionally, proper ventilation should be ensured when working with this chemical to minimize the risk of inhalation.
Hazard statements for 1,6-di-O-phosphono-D-fructose include the potential for causing skin irritation, serious eye damage, and respiratory irritation. This compound may also be harmful if swallowed, leading to gastrointestinal discomfort. It is important to avoid direct contact with the substance and take necessary precautions to prevent any exposure. In case of ingestion, immediate medical attention should be sought to prevent any adverse effects.
Precautionary statements for 1,6-di-O-phosphono-D-fructose include the need to wear protective gloves, clothing, and eye/face protection when handling this compound. It is recommended to work in a well-ventilated area and avoid breathing in any fumes or vapors. In case of skin contact, the affected area should be immediately washed with soap and water. If eye contact occurs, rinse thoroughly with water for several minutes while removing contact lenses if present. Any clothing or equipment contaminated with the substance should be removed and cleaned before reuse.
🔬 Potential Research Directions
One potential research direction for 1,6-di-O-phosphono-D-fructose is its potential as a therapeutic agent for diseases such as osteoporosis or osteoarthritis. Studies could investigate its impact on bone health and joint inflammation in animal models.
Another area of interest could be its potential as a medical imaging agent. Research could explore its ability to selectively target specific cells or tissues for imaging purposes, such as in cancer detection or monitoring disease progression.
Furthermore, studies could be conducted to understand the mechanism of action of 1,6-di-O-phosphono-D-fructose on cellular signaling pathways. This could provide insight into its potential as a novel drug target for conditions such as diabetes or cardiovascular disease.
🧪 Related Compounds
One similar compound to 1,6-di-O-phosphono-D-fructose based on molecular structure is 1,6-di-O-sulfono-D-fructose. This compound features a similar structure to 1,6-di-O-phosphono-D-fructose, except with sulfur replacing the phosphorus atom in the molecule. This substitution leads to similar chemical properties and potential applications in biological systems.
Another compound related to 1,6-di-O-phosphono-D-fructose is 1,6-di-O-acetyl-D-fructose. In this compound, acetyl groups replace the phosphono groups found in 1,6-di-O-phosphono-D-fructose. This substitution alters the chemical properties of the molecule, potentially affecting its biological activity and interactions.
Additionally, another related compound to 1,6-di-O-phosphono-D-fructose is 1,6-di-O-methyl-D-fructose. In this compound, methyl groups replace the phosphono groups present in 1,6-di-O-phosphono-D-fructose. This structural modification can influence the compound’s solubility, stability, and interactions with other molecules in biological systems.
