1,3,5-Trimethyl-1,3,5-triazacyclohexane, also known as cryptand 222, is a well-known cyclic molecule with three nitrogen atoms and three methyl groups. This compound has significant relevance in everyday life due to its application as a complexing agent in various fields such as chemistry, material science, and biology.
In chemistry, 1,3,5-Trimethyl-1,3,5-triazacyclohexane is used as a chelating agent to selectively bind metal ions, which is crucial in the purification and separation of metals. This compound also plays a vital role in catalysis and coordination chemistry.
In material science, cryptand 222 is utilized in the synthesis of polymers, coordination polymers, and metal-organic frameworks, leading to advancements in drug delivery systems, sensors, and energy storage devices.
Furthermore, in biology, 1,3,5-Trimethyl-1,3,5-triazacyclohexane is applied in biochemical studies and as a ligand for metalloenzymes, contributing to a better understanding of biological processes and potential therapeutic applications.
Overall, the versatility and effectiveness of 1,3,5-Trimethyl-1,3,5-triazacyclohexane make it a crucial component in various scientific disciplines, impacting our daily lives through its contributions to research, technology, and innovation.
Table of Contents:
- 💡 Commercial Applications
- ⚗️ Chemical & Physical Properties
- 🏭 Production & Procurement
- ⚠️ Safety Considerations
- 🔬 Potential Research Directions
- 🧪 Related Compounds
💡 Commercial Applications
1,3,5-Trimethyl-1,3,5-triazacyclohexane, also known as TMTCH, is commonly used in commercial and industrial applications as a chelating agent. It is often employed in the chemical industry to remove metal ions from various solutions, as it forms stable complexes with metals like copper, lead, and zinc. Additionally, TMTCH can be found in the formulation of detergents and cleaning products, where its chelating properties help enhance their effectiveness.
In the realm of drug and medication applications, 1,3,5-Trimethyl-1,3,5-triazacyclohexane is utilized as a complexing agent in pharmaceutical formulations. Due to its ability to form stable complexes with metal ions, TMTCH is often included in drug delivery systems to improve the solubility and stability of certain pharmaceutical compounds. Additionally, TMTCH can be found in some medical devices where it is used to prevent the formation of metal ion deposits.
It is worth noting that 1,3,5-Trimethyl-1,3,5-triazacyclohexane’s chelating properties make it a versatile compound with a wide range of applications across various industries. Its role as a complexing agent in commercial and industrial settings, as well as in pharmaceutical formulations, highlights its importance in the development and production of various products and technologies.
⚗️ Chemical & Physical Properties
1,3,5-Trimethyl-1,3,5-triazacyclohexane appears as a colorless, odorless liquid at room temperature. It is a cyclic organic compound with a unique six-membered ring structure.
1,3,5-Trimethyl-1,3,5-triazacyclohexane has a molar mass of approximately 177.24 g/mol and a density of about 0.95 g/cm3. Compared to common food items like water (molar mass = 18.02 g/mol, density = 1 g/cm3) and sugar (molar mass = 342.30 g/mol, density = 1.59 g/cm3), this compound is lighter in molar mass and less dense.
The melting point of 1,3,5-Trimethyl-1,3,5-triazacyclohexane is around -41°C, while the boiling point is approximately 169°C. In comparison to common food items such as butter (melting point = 32°C, boiling point = 150°C) and honey (melting point = approx. 30°C, boiling point = approx. 100°C), this compound has a lower melting point but a higher boiling point.
1,3,5-Trimethyl-1,3,5-triazacyclohexane is sparingly soluble in water and exhibits low viscosity. These properties differ from common food items like salt (high solubility in water) and honey (higher viscosity), highlighting the unique characteristics of this compound in aqueous solutions.
🏭 Production & Procurement
1,3,5-Trimethyl-1,3,5-triazacyclohexane, also known as TMTCH, is produced through a multi-step synthesis process involving the reaction of 1,3,5-trihalocyclohexane with excess ethylenediamine in the presence of a catalyst. This reaction results in the formation of the desired product, which can then be isolated and purified through various techniques such as recrystallization or column chromatography.
Once produced, 1,3,5-Trimethyl-1,3,5-triazacyclohexane can be procured from chemical suppliers and manufacturers who specialize in the production and distribution of specialty chemicals. These suppliers typically offer the compound in various purities and quantities to accommodate the needs of different industries and research applications. The compound can be transported in sealed containers, such as glass bottles or plastic drums, to ensure its stability and prevent contamination during transit.
1,3,5-Trimethyl-1,3,5-triazacyclohexane is commonly used in the synthesis of coordination complexes and as a ligand in metal-catalyzed reactions. Due to its versatile nature and unique structural properties, the compound is in demand by researchers and industries engaged in organic synthesis, catalysis, and materials science. It is important for users to store and handle the compound according to the guidelines provided by the supplier to ensure its stability and safety.
⚠️ Safety Considerations
Safety considerations for 1,3,5-Trimethyl-1,3,5-triazacyclohexane, also known as MeCyclam, include the potential for skin and eye irritation upon contact. It is important to handle this compound with care, wearing appropriate protective equipment such as gloves and goggles. Additionally, it is recommended to work with MeCyclam in a well-ventilated area to avoid inhaling any vapors that may be emitted.
Hazard statements for 1,3,5-Trimethyl-1,3,5-triazacyclohexane typically include warnings about its potential to cause skin and eye irritation. It may also be harmful if swallowed or inhaled, and could cause respiratory irritation. It is important to use caution when working with this compound to minimize the risk of any adverse effects on one’s health.
Precautionary statements for 1,3,5-Trimethyl-1,3,5-triazacyclohexane often advise storing it in a cool, dry place away from heat and direct sunlight. It is important to keep it tightly sealed in its original container and away from incompatible materials. When handling MeCyclam, it is recommended to use proper protective equipment and to wash hands thoroughly after contact to prevent any potential skin irritation.
🔬 Potential Research Directions
Potential research directions for 1,3,5-Trimethyl-1,3,5-triazacyclohexane could include studying its coordination chemistry with various metal ions to explore its potential as a chelating agent in catalysis or material science applications.
Additionally, investigations into the synthesis and characterization of functionalized derivatives of 1,3,5-Trimethyl-1,3,5-triazacyclohexane could provide valuable insights into structure-activity relationships and potential biological applications.
Furthermore, exploring the reactivity of 1,3,5-Trimethyl-1,3,5-triazacyclohexane towards various organic transformations could lead to the development of new synthetic methodologies and the discovery of novel chemical reactivity patterns.
🧪 Related Compounds
One similar compound to 1,3,5-Trimethyl-1,3,5-triazacyclohexane is 1,3,5-Trimethyl-1,3,5-trioxaane. This compound has a similar molecular structure, with three oxygen atoms instead of nitrogen atoms present in the ring. This change in the heteroatom results in different chemical properties and reactivity compared to the nitrogen-containing compound.
Another analogous compound is 1,3,5-Trimethyl-1,3,5-trithiane, which also shares a similar molecular structure with the aforementioned compound. In this case, sulfur atoms replace the nitrogen atoms in the ring, leading to distinct chemical properties. Despite the structural similarities, the presence of sulfur atoms alters the compound’s reactivity and potential applications.
1,3,5-Trimethyl-1,3,5-trialkyl-1,3,5-triazacyclohexanes represent a broader class of compounds that share structural similarities with the original compound. By varying the alkyl substituents on the nitrogen atoms, different compounds with similar ring structures can be synthesized. These derivatives exhibit diverse chemical properties based on the nature of the alkyl groups attached to the nitrogen atoms, offering a range of potential applications in various fields.
