1,3-Naphthalenediol is a chemical compound with various practical applications in everyday life. This compound is commonly used in hair dyes, as it acts as a colorant and aids in achieving desired hair hues. Additionally, 1,3-Naphthalenediol is utilized in the production of pharmaceuticals and as a precursor in the manufacturing of perfumes and antioxidants. Its relevance lies in its versatility across several industries, contributing to the enhancement of consumer products and their overall quality.
Table of Contents:
Commercial Applications
Chemical & Physical Properties
Production & Procurement
Safety Considerations
Potential Research Directions
Related Compounds
Commercial Applications
1,3-Naphthalenediol, also known as 1,3-dihydroxynaphthalene, finds several commercial and industrial applications due to its properties. It is used as a precursor in the synthesis of various dyes and pigments, particularly in the production of fluorescent whitening agents. Additionally, 1,3-Naphthalenediol is utilized in the manufacturing of photographic chemicals and as a corrosion inhibitor in metalworking processes.
In the field of drug and medication applications, 1,3-Naphthalenediol has shown potential as an antioxidant and antimicrobial agent. Studies have demonstrated its ability to scavenge free radicals, which are associated with various diseases and aging processes. Furthermore, research suggests that 1,3-Naphthalenediol may possess antibacterial properties, making it a promising candidate for the development of new antibiotics.
Chemical & Physical Properties
1,3-Naphthalenediol is a white crystalline solid with no noticeable odor. It is typically found in the form of fine powder or small crystals.
The molar mass of 1,3-Naphthalenediol is approximately 162.14 g/mol, and its density is around 1.38 g/cm³. This places it in the range of typical food items in terms of molar mass and density, such as sucrose and salt.
1,3-Naphthalenediol has a melting point of about 158-160°C and a boiling point of around 376-378°C. These values are notably higher compared to common food items like sugar and water, which have lower melting and boiling points.
1,3-Naphthalenediol is sparingly soluble in water, forming a slightly hazy solution. It has a relatively low viscosity, similar to that of maple syrup. In comparison to common food items, it is less soluble in water and has a lower viscosity.
Production & Procurement
1,3-Naphthalenediol, also known as 1,3-dihydroxynaphthalene, is primarily produced through the nitric acid oxidation of 1,3-dihydroxynaphthalene. This reaction typically takes place in a suitable solvent at elevated temperatures.
The production of 1,3-Naphthalenediol on an industrial scale involves careful control of reaction conditions to ensure high yields and purity. Various methods, including chromatography, can be used to isolate and purify the final product.
Once 1,3-Naphthalenediol is produced, it can be procured through chemical suppliers or manufacturers that specialize in fine chemicals. The compound is often transported in sealed containers to prevent contamination or degradation during transit.
Care should be taken when procuring and handling 1,3-Naphthalenediol, as it is a potentially hazardous chemical that may require special storage and handling procedures. Proper safety precautions should be followed according to established guidelines and regulations.
Safety Considerations
Safety considerations for 1,3-Naphthalenediol include the fact that it is a skin irritant and can cause sensitization upon contact. It should be handled with caution, wearing appropriate protective clothing and gloves to prevent skin exposure. In case of inhalation, move to fresh air and seek medical attention if necessary.
Hazard statements for 1,3-Naphthalenediol include “Causes skin irritation” and “May cause an allergic skin reaction.” These statements indicate the potential risks associated with exposure to this compound, particularly in terms of skin contact and sensitization. It is important to take appropriate precautions to avoid these hazards.
Precautionary statements for 1,3-Naphthalenediol include “Wear protective gloves/eye protection/face protection” and “Wash hands thoroughly after handling.” These statements emphasize the importance of using proper personal protective equipment and practicing good hygiene to minimize the risks of exposure to this compound. It is crucial to follow these precautions to ensure safe handling of 1,3-Naphthalenediol.
Potential Research Directions
One potential research direction for 1,3-Naphthalenediol involves investigating its antioxidant properties and potential applications in combating oxidative stress-related diseases. Studies could focus on understanding the mechanisms by which 1,3-Naphthalenediol scavenges free radicals and protects cells from damage.
Another avenue of research could explore the potential therapeutic effects of 1,3-Naphthalenediol in cancer treatment. Investigations could examine its ability to inhibit cell proliferation and induce apoptosis in cancer cells, as well as its synergistic effects with existing chemotherapeutic agents.
Furthermore, research could be conducted on the environmental impact of 1,3-Naphthalenediol and its derivatives. Studies could assess its toxicity levels, biodegradability, and potential for bioaccumulation in ecosystems, in order to evaluate its safety for human health and the environment.
Related Compounds
One compound similar in structure to 1,3-Naphthalenediol is 1,4-Naphthalenediol. This compound shares a similar molecular formula but differs in the position of the hydroxyl groups on the naphthalene ring. The presence of hydroxyl groups on adjacent carbons in both compounds results in similar chemical reactivity and potential applications.
Another analogous compound is Resorcinol, which contains two hydroxyl groups on a benzene ring. Resorcinol differs from both 1,3-Naphthalenediol and 1,4-Naphthalenediol in terms of the ring structure, as it lacks the condensed naphthalene framework. However, Resorcinol shares similar chemical properties due to the presence of hydroxyl groups on adjacent carbons, allowing for similar reactivity in certain chemical reactions.
Similarly, Catechol is a compound with two hydroxyl groups adjacent to each other on a benzene ring. Catechol is structurally different from both 1,3-Naphthalenediol and 1,4-Naphthalenediol due to the lack of a naphthalene backbone. Despite this structural variation, Catechol exhibits similar chemical behavior to the naphthalenediols due to the presence of adjacent hydroxyl groups, allowing for analogous reactivity in certain chemical reactions.
