12-Hydroxy-5,8,10-heptadecatrienoic acid is a fatty acid that plays a crucial role in human health. It is a precursor to important signaling molecules in the body that regulate inflammation, blood clotting, and blood vessel function. These functions impact everyday life as they play a role in various health conditions such as heart disease, diabetes, and arthritis. Additionally, this fatty acid is found in various foods and dietary supplements, making it relevant to individuals seeking to maintain a healthy lifestyle.
Table of Contents:
- 💡 Commercial Applications
- ⚗️ Chemical & Physical Properties
- 🏭 Production & Procurement
- ⚠️ Safety Considerations
- 🔬 Potential Research Directions
- 🧪 Related Compounds
💡 Commercial Applications
12-Hydroxy-5,8,10-heptadecatrienoic acid, also known as Hydoxypolyunsaturated fatty acid (HPFA), has various commercial and industrial applications. It is commonly used in the production of cosmetics, such as skin creams and lotions, due to its moisturizing properties. Additionally, HPFA is utilized in the manufacturing of dietary supplements and nutraceuticals for its potential health benefits.
In the realm of drug and medication applications, 12-Hydroxy-5,8,10-heptadecatrienoic acid has shown promise in the treatment of inflammatory conditions due to its anti-inflammatory properties. It is being explored for its potential use in pharmaceutical formulations for conditions such as arthritis and other inflammatory diseases. Additionally, HPFA may also have potential applications in the field of dermatology for the treatment of skin conditions such as eczema and psoriasis.
⚗️ Chemical & Physical Properties
12-Hydroxy-5,8,10-heptadecatrienoic acid is a colorless, odorless compound with a powdery appearance.
The molar mass of 12-Hydroxy-5,8,10-heptadecatrienoic acid is approximately 296.47 g/mol, with a density of around 0.93 g/mL. This molar mass is comparable to that of common food items such as olive oil, while the density is similar to water.
The melting point of 12-Hydroxy-5,8,10-heptadecatrienoic acid is around 65-68°C, and the boiling point is approximately 275-280°C. These values are higher than those of common food items like butter, which typically have lower melting and boiling points.
12-Hydroxy-5,8,10-heptadecatrienoic acid is insoluble in water but soluble in organic solvents, exhibiting a moderate viscosity. This solubility and viscosity are similar to that of fatty acids found in dairy products like cheese.
🏭 Production & Procurement
12-Hydroxy-5,8,10-heptadecatrienoic acid, also known as 12-HHT, is produced through a series of enzymatic reactions involving the oxidation of arachidonic acid. These enzymatic reactions are typically carried out by lipoxygenases, which are enzymes responsible for the oxidation of polyunsaturated fatty acids such as arachidonic acid.
In order to procure 12-Hydroxy-5,8,10-heptadecatrienoic acid, one must first obtain arachidonic acid, which is a polyunsaturated fatty acid found in various plant and animal sources. Arachidonic acid can be extracted from sources such as soybean oil, sunflower oil, and animal fats. Once arachidonic acid is obtained, it can be subjected to enzymatic reactions using lipoxygenases to produce 12-Hydroxy-5,8,10-heptadecatrienoic acid.
Transportation of 12-Hydroxy-5,8,10-heptadecatrienoic acid is typically done in its purified form, either as a liquid or solid depending on the specific application. It is essential to handle and transport this compound with care to prevent degradation or contamination. Proper labeling and documentation of the compound during transportation are also crucial to ensure traceability and compliance with regulations.
⚠️ Safety Considerations
Safety considerations for 12-Hydroxy-5,8,10-heptadecatrienoic acid should be taken seriously due to its potential hazards. This compound should be handled with care to avoid skin and eye contact, ingestion, or inhalation. Personal protective equipment, such as gloves, goggles, and a lab coat, should be worn when working with this substance to minimize any risks of exposure.
It is important to store 12-Hydroxy-5,8,10-heptadecatrienoic acid in a well-ventilated area away from heat sources and incompatible materials. Proper labeling of containers is essential to avoid confusion and accidental exposure. In case of a spill, appropriate cleanup procedures should be followed to prevent any environmental contamination or harm to individuals working in the area. When disposing of this compound, local regulations for hazardous waste disposal should be strictly adhered to.
Hazard statements for 12-Hydroxy-5,8,10-heptadecatrienoic acid include “Causes skin irritation” and “Causes serious eye damage.” These hazards indicate the potential risks associated with direct contact of this compound with skin or eyes. It is important to take necessary precautions to prevent these hazards, such as wearing protective clothing and eyewear when handling 12-Hydroxy-5,8,10-heptadecatrienoic acid.
Precautionary statements for 12-Hydroxy-5,8,10-heptadecatrienoic acid include “Wear protective gloves/protective clothing/eye protection/face protection” and “IF ON SKIN: Wash with plenty of water.” These statements emphasize the importance of using appropriate personal protective equipment and following proper hygiene practices when working with this compound. It is crucial to follow these precautions to minimize the risks of exposure and ensure safety while handling 12-Hydroxy-5,8,10-heptadecatrienoic acid.
🔬 Potential Research Directions
Potential research directions for 12-Hydroxy-5,8,10-heptadecatrienoic acid include its biological significance and potential therapeutic applications. Studies may focus on elucidating its role in inflammatory pathways and identifying potential targets for drug development.
Furthermore, research could explore the synthesis and metabolism of 12-Hydroxy-5,8,10-heptadecatrienoic acid in various biological systems. Understanding its production and breakdown may provide insights into its physiological functions and potential dysregulation in disease states.
Additionally, investigations into the signaling pathways modulated by 12-Hydroxy-5,8,10-heptadecatrienoic acid could reveal novel therapeutic strategies for conditions such as inflammation, cancer, and metabolic disorders. Targeting these pathways may lead to the development of new drugs with improved efficacy and reduced side effects.
🧪 Related Compounds
One similar compound to 12-Hydroxy-5,8,10-heptadecatrienoic acid is 13-Hydroxy-5,8,10-heptadecatrienoic acid. This compound differs only by the position of the hydroxyl group, located on the 13th carbon atom instead of the 12th.
Another similar compound is 12-Hydroxy-5,8,10-octadecatrienoic acid. This compound shares the same hydroxyl group position as 12-Hydroxy-5,8,10-heptadecatrienoic acid but has an additional carbon atom in its structure.
Additionally, 12-Hydroxy-5,8,10-hexadecatrienoic acid is a similar compound to 12-Hydroxy-5,8,10-heptadecatrienoic acid. This compound has a shorter carbon chain length, consisting of 16 carbon atoms, but shares the same position of the hydroxyl group.
