1,2-Dimethyl-4-nitrobenzene is a chemical compound that is commonly used in the production of various consumer products, such as dyes, fragrances, and pharmaceuticals. Despite its technical nature, this compound plays a significant role in everyday life by contributing to the creation of items that are commonly found in households around the world. Its presence in these products highlights its importance in various industries and underscores its relevance to the daily lives of individuals.
Table of Contents:
- 💡 Commercial Applications
- ⚗️ Chemical & Physical Properties
- 🏭 Production & Procurement
- ⚠️ Safety Considerations
- 🔬 Potential Research Directions
- 🧪 Related Compounds
💡 Commercial Applications
1,2-Dimethyl-4-nitrobenzene, also known as 4-Nitro-1,2-dimethylbenzene, finds various commercial and industrial applications. This compound is commonly used as an intermediate in the manufacturing of dyes, pigments, and pharmaceuticals. Additionally, 1,2-Dimethyl-4-nitrobenzene can be utilized in the production of rubber chemicals, plastics, and crop protection agents.
In the realm of drug and medication applications, 1,2-Dimethyl-4-nitrobenzene plays a role in the synthesis of certain pharmaceutical compounds. This chemical is used in the preparation of various drugs, including antihistamines, anti-inflammatory medications, and antibiotics. Moreover, 1,2-Dimethyl-4-nitrobenzene can be employed in the pharmaceutical industry as a building block for creating novel drug molecules with specific therapeutic properties.
⚗️ Chemical & Physical Properties
1,2-Dimethyl-4-nitrobenzene is a colorless liquid with a faint aromatic odor. It is commonly used in the production of dyes and other chemicals due to its unique chemical properties.
With a molar mass of 161.15 g/mol and a density of 1.133 g/cm³, 1,2-Dimethyl-4-nitrobenzene is similar in molar mass to sugar (180.16 g/mol) but denser than water (1 g/cm³).
1,2-Dimethyl-4-nitrobenzene has a melting point of -30 °C and a boiling point of 239 °C. These values are higher than common food items such as butter and chocolate with respect to melting and boiling points.
1,2-Dimethyl-4-nitrobenzene is insoluble in water and exhibits low viscosity. This contrasts with common food items like sugar and salt, which dissolve readily in water and have varying viscosities.
🏭 Production & Procurement
1,2-Dimethyl-4-nitrobenzene, also known as p-xylene nitration product, is produced through the nitration reaction of p-xylene with a mixture of concentrated sulfuric acid and nitric acid. This reaction leads to the formation of the desired compound, which is further purified and isolated through processes such as recrystallization.
The procurement of 1,2-Dimethyl-4-nitrobenzene involves the purchasing of p-xylene, sulfuric acid, and nitric acid from reputable chemical suppliers. These reagents are then mixed in the appropriate stoichiometric ratios to carry out the nitration reaction. The resulting product can be extracted and purified using standard laboratory techniques.
Once procured and synthesized, 1,2-Dimethyl-4-nitrobenzene can be safely transported in glass or plastic containers to prevent leakage and contamination. Proper labeling and documentation of the compound are essential during transportation to ensure regulatory compliance and safe handling practices. It is recommended to store the compound in a cool, dry place away from direct sunlight and sources of heat.
⚠️ Safety Considerations
Safety considerations for 1,2-Dimethyl-4-nitrobenzene should be taken seriously due to its potential hazards. This chemical is flammable and may pose a fire hazard. It is also harmful if swallowed, inhaled, or absorbed through the skin, and can cause irritation to the respiratory system and skin. Proper personal protective equipment should be worn when handling this substance, including gloves, safety goggles, and a lab coat.
In terms of hazard statements, it is important to note that 1,2-Dimethyl-4-nitrobenzene is classified as harmful if swallowed, harmful in contact with skin, and harmful if inhaled. It may cause skin irritation and serious eye irritation. This chemical should be stored in a well-ventilated area, away from heat, sparks, and open flames. It is crucial to handle this substance with care to avoid any potential hazards.
Precautionary statements for 1,2-Dimethyl-4-nitrobenzene include wearing protective gloves, clothing, eye protection, and face protection. Avoid breathing vapors, mist, or gas. Use only outdoors or in a well-ventilated area. Keep away from heat, hot surfaces, sparks, open flames, and other sources of ignition. In case of fire, use water spray, alcohol-resistant foam, dry chemical, or carbon dioxide to extinguish the flames. It is essential to follow all safety guidelines and protocols when working with this chemical to minimize any risks to health and safety.
🔬 Potential Research Directions
Research on 1,2-Dimethyl-4-nitrobenzene may focus on its potential uses in organic synthesis due to its unique chemical structure and reactivity.
Further investigations could explore its toxicity and environmental impact, as nitrobenzenes are known to be toxic to aquatic organisms and potentially harmful to human health.
Studies may also delve into the development of new methods for the synthesis of 1,2-Dimethyl-4-nitrobenzene, aiming to improve efficiency and yield in industrial processes.
Additionally, research efforts could be directed towards exploring the biological activity of 1,2-Dimethyl-4-nitrobenzene and its potential applications in pharmaceuticals or agrochemicals.
🧪 Related Compounds
One similar compound to 1,2-Dimethyl-4-nitrobenzene is 1,3-Dimethyl-4-nitrobenzene. This compound has a similar molecular structure to 1,2-Dimethyl-4-nitrobenzene, with the nitro group located at position 4 of the benzene ring. However, in this compound, the two methyl groups are located at positions 1 and 3 of the benzene ring, rather than positions 1 and 2.
Another similar compound is 1,2-Dimethyl-5-nitrobenzene. Like 1,2-Dimethyl-4-nitrobenzene, this compound has two methyl groups attached to the benzene ring, with the nitro group located at position 5. The molecular structure of 1,2-Dimethyl-5-nitrobenzene is therefore similar to that of 1,2-Dimethyl-4-nitrobenzene, with differences in the position of the nitro group.
Additionally, 1,2,4-Trimethyl-3-nitrobenzene is another compound with a molecular structure similar to 1,2-Dimethyl-4-nitrobenzene. In this compound, there are three methyl groups attached to the benzene ring, with the nitro group located at position 3. While the number and positioning of the methyl groups differ from 1,2-Dimethyl-4-nitrobenzene, the presence of the nitro group on the benzene ring makes these compounds structurally similar.
