1-Pyrroline-4-hydroxy-2-carboxylate is a crucial intermediate in the biosynthesis of proline, an amino acid that plays a vital role in protein structure and function. Proline is found in a variety of foods such as meat, dairy products, and nuts, and is essential for the proper growth and maintenance of the human body. Therefore, 1-Pyrroline-4-hydroxy-2-carboxylate indirectly impacts everyday life by contributing to the production of a fundamental building block of life. Its significance lies in its role in the maintenance of human health and well-being.
Table of Contents:
- 💡 Commercial Applications
- ⚗️ Chemical & Physical Properties
- 🏭 Production & Procurement
- ⚠️ Safety Considerations
- 🔬 Potential Research Directions
- 🧪 Related Compounds
💡 Commercial Applications
1-Pyrroline-4-hydroxy-2-carboxylate, commonly known as P4H2C, is a compound with various commercial and industrial applications. It is primarily used in the production of food flavorings, specifically in the enhancement of meat and seafood flavors. P4H2C is also utilized in the manufacturing of perfumes and fragrances due to its aromatic properties.
In the pharmaceutical industry, 1-Pyrroline-4-hydroxy-2-carboxylate has shown potential for drug and medication applications. It has been studied for its antioxidant properties and its ability to neutralize free radicals in the body, which can help prevent cellular damage. Additionally, P4H2C has been investigated for its potential role in cancer treatment, as it may inhibit tumor growth and metastasis.
Overall, 1-Pyrroline-4-hydroxy-2-carboxylate demonstrates versatility in both commercial and industrial sectors, as well as promising applications in the field of medicine and healthcare. Its unique chemical properties make it a valuable ingredient in various products and could potentially lead to innovative advancements in pharmaceutical research.
⚗️ Chemical & Physical Properties
1-Pyrroline-4-hydroxy-2-carboxylate appears as a white crystalline solid with no distinct odor. It is generally stable under normal conditions and does not exhibit any strong or offensive smells.
With a molar mass of approximately 159.1 g/mol and a density of around 1.42 g/cm³, 1-Pyrroline-4-hydroxy-2-carboxylate is similar in size and weight to common food items such as sugars and organic acids. Its density is higher than water, making it slightly denser than most food items.
The compound has a melting point of around 195-200°C and a boiling point of approximately 252-257°C. These values are higher than those of many food items, indicating that 1-Pyrroline-4-hydroxy-2-carboxylate is more heat-resistant and stable under high temperatures compared to most common food components.
1-Pyrroline-4-hydroxy-2-carboxylate is readily soluble in water and exhibits a low viscosity. This high water solubility and low viscosity make it similar to certain food additives or preservatives commonly found in liquid food products such as salad dressings or sauces.
🏭 Production & Procurement
1-Pyrroline-4-hydroxy-2-carboxylate, a vital intermediate in the biosynthesis of proline, is typically synthesized from L-glutamic acid. The production process involves several steps including the reduction of L-glutamic acid to L-glutamate semialdehyde, which is then cyclized to form 1-Pyrroline-4-hydroxy-2-carboxylate. This compound is of significant interest due to its role in various biochemical pathways.
In order to procure 1-Pyrroline-4-hydroxy-2-carboxylate for research or industrial purposes, one must typically turn to chemical suppliers specialized in rare or specialized compounds. These suppliers may offer the compound in various forms such as powder or solution depending on the needs of the consumer. Once procured, the compound can be transported using standard methods for handling sensitive chemicals.
Transportation of 1-Pyrroline-4-hydroxy-2-carboxylate generally requires compliance with safety regulations for handling and shipping hazardous materials. Depending on the quantity and purity of the compound, specialized containers or packaging may be necessary to ensure safe transport. It is advisable to work with experienced professionals or consult relevant guidelines to ensure secure and efficient transportation of the compound.
⚠️ Safety Considerations
Safety considerations for 1-Pyrroline-4-hydroxy-2-carboxylate are of utmost importance due to its potential hazards. This compound should be handled with care and appropriate personal protective equipment should be worn when working with it. It is recommended to work with 1-Pyrroline-4-hydroxy-2-carboxylate in a well-ventilated area to minimize exposure to fumes or vapors. Additionally, the compound should be stored in a tightly sealed container away from heat, sparks, and open flames to prevent any potential fire hazards.
Hazard statements for 1-Pyrroline-4-hydroxy-2-carboxylate include the following: May cause skin irritation. May cause eye irritation. May cause respiratory irritation. These hazard statements indicate the potential risks associated with exposure to this compound and emphasize the importance of taking necessary precautions when handling it.
Precautionary statements for 1-Pyrroline-4-hydroxy-2-carboxylate include the following: Wear protective gloves/eye protection/face protection. Wash hands thoroughly after handling. Avoid breathing dust/fume/gas/mist/vapors/spray. These precautionary statements highlight the importance of using proper personal protective equipment, practicing good hygiene, and minimizing exposure to the compound to ensure safe handling and use.
🔬 Potential Research Directions
One potential research direction for 1-Pyrroline-4-hydroxy-2-carboxylate is the investigation of its role in various biochemical pathways within organisms. Studies could focus on elucidating the enzymatic reactions involved in its biosynthesis and metabolism, as well as its potential functions as a signaling molecule in cellular processes.
Another area of exploration could involve the physiological significance of 1-Pyrroline-4-hydroxy-2-carboxylate in different organisms, including plants and animals. Researchers may seek to understand its impact on growth, development, stress responses, and other biological functions, as well as its potential as a biomarker for certain physiological conditions.
Furthermore, the potential pharmacological properties of 1-Pyrroline-4-hydroxy-2-carboxylate could be investigated, including its ability to modulate cellular processes or serve as a therapeutic target for diseases. Research in this area may lead to the development of novel drugs or therapies that target 1-Pyrroline-4-hydroxy-2-carboxylate metabolism or signaling pathways in various pathological conditions.
🧪 Related Compounds
One similar compound to 1-Pyrroline-4-hydroxy-2-carboxylate based on molecular structure is 1-Pyrroline-4-carboxylate. This compound has a pyrroline ring with a carboxylate group at the 4-position, similar to 1-Pyrroline-4-hydroxy-2-carboxylate. The presence of the carboxylate group imparts similar chemical reactivity and properties to the two compounds.
Another related compound is 1-Pyrroline-2-carboxylate, which shares structural similarities with 1-Pyrroline-4-hydroxy-2-carboxylate. Both compounds contain a pyrroline ring, albeit with different substitution patterns. The carboxylate group at the 2-position in 1-Pyrroline-2-carboxylate distinguishes it from 1-Pyrroline-4-hydroxy-2-carboxylate, but their overall molecular structures are comparable.
Additionally, N-methyl-1-Pyrroline-4-hydroxy-2-carboxylate is a related compound that features a methyl group attached to the nitrogen atom of the pyrroline ring. This modification alters the chemical properties of the compound compared to 1-Pyrroline-4-hydroxy-2-carboxylate, while still retaining structural similarities such as the presence of the hydroxy and carboxylate groups.
