1-Phenylethanol

1-Phenylethanol, a compound with a chemical structure consisting of a benzene ring attached to a hydroxyl group, holds relevance in everyday life due to its various applications. In addition to being utilized as a fragrance ingredient in perfumes and personal care products, 1-Phenylethanol also serves as a precursor in the synthesis of pharmaceuticals and agrochemicals. Furthermore, it is found in certain food items and beverages, contributing to their aroma and flavor profiles. Overall, the versatility of 1-Phenylethanol underscores its significance in enhancing sensory experiences and supporting numerous industries.

Table of Contents:

💡 Commercial Applications

1-Phenylethanol, also known as alpha-Methylbenzyl alcohol, is a common chemical compound utilized in various commercial and industrial applications. It is commonly used as a fragrance ingredient in cosmetics, soaps, and perfumes due to its pleasant rose-like odor. Additionally, 1-Phenylethanol is used as a flavoring agent in food products such as chewing gum and candies.

In the pharmaceutical industry, 1-Phenylethanol has applications in drug formulations and medications. It is often used as a sedative in anesthesia due to its calming effects on the central nervous system. Furthermore, 1-Phenylethanol has antimicrobial properties, making it a valuable ingredient in topical antiseptic solutions and disinfectants. Additionally, it is used in the production of certain medications for its potential therapeutic effects.

Overall, 1-Phenylethanol serves as a versatile compound with various practical applications in both commercial and industrial sectors. Its unique properties make it a valuable ingredient in a wide range of products, from fragrances and flavors to pharmaceutical formulations and medications. Its role in these industries highlights its importance as a functional compound with diverse applications.

⚗️ Chemical & Physical Properties

1-Phenylethanol, also known as phenyl ethanol or benzyl alcohol, is a colorless liquid that has a pleasant floral, rose-like odor. It is commonly used as a fragrance ingredient in perfumes and cosmetics due to its appealing scent.

With a molar mass of 122.16 g/mol and a density of 1.045 g/cm3, 1-Phenylethanol is similar in molar mass to common household items like baking soda (NaHCO3) and slightly less dense than water. This makes it relatively light compared to heavier household items like table salt (NaCl) and sugar (C12H22O11).

1-Phenylethanol has a melting point of 20.2°C and a boiling point of 205°C. This places it within the range of melting points for common household items such as butter (30-35°C) and vegetable oil (14-24°C), but with a higher boiling point than most household liquids like water (100°C) and vinegar (100.6°C).

1-Phenylethanol is sparingly soluble in water, but more soluble in organic solvents like ethanol and acetone. It has a relatively low viscosity compared to common household items like honey and molasses, which are much thicker and more viscous in nature.

🏭 Production & Procurement

1-Phenylethanol, also known as alpha-Methylbenzyl alcohol, is typically produced through the reduction of acetophenone using reducing agents such as sodium borohydride or lithium aluminum hydride. This reaction results in the formation of the desired product along with some undesirable byproducts that need to be removed through purification processes.

Once 1-Phenylethanol has been successfully synthesized, it can be procured from chemical suppliers that specialize in providing a wide range of fine chemicals and intermediates. The compound is typically supplied in liquid form and is packaged in appropriate containers for transportation to customers. Proper handling and storage procedures should be followed to ensure the integrity and quality of the product during transit.

Transportation of 1-Phenylethanol is typically carried out using standard chemical transport methods, such as road, rail, or air transportation. The compound is classified as a hazardous material due to its flammable nature, and strict regulations must be followed to ensure safety during transportation. Proper labeling, packaging, and documentation are required to comply with transportation regulations and ensure the safe delivery of the product to its destination.

⚠️ Safety Considerations

Safety considerations for 1-Phenylethanol should be taken seriously due to its potential hazards. This compound is irritating to the skin, eyes, and respiratory system. Therefore, it is essential to handle it with caution and wear appropriate protective equipment such as gloves, goggles, and a mask when working with it. Additionally, 1-Phenylethanol should be stored in a well-ventilated area away from heat and sources of ignition to prevent the risk of fire or explosion.

In terms of pharmacology, 1-Phenylethanol is known for its aromatic properties and is often used in perfumes, flavors, and cosmetics. It has a pleasant floral odor reminiscent of roses, making it a popular choice in the fragrance industry. 1-Phenylethanol is also used as a preservative in certain products due to its antimicrobial properties. When ingested or inhaled in high concentrations, it can have sedative effects on the central nervous system.

The hazard statements for 1-Phenylethanol include its flammable nature, as it can easily catch fire if exposed to heat or sparks. It is also classified as harmful if swallowed or inhaled, and may cause irritation to the skin, eyes, and respiratory system upon contact. Moreover, prolonged or repeated exposure to 1-Phenylethanol may lead to sensitization or allergic reactions in some individuals. Therefore, it is crucial to follow proper handling procedures and avoid direct contact with this compound.

Precautionary statements for 1-Phenylethanol include avoiding skin and eye contact, inhaling its vapors, and ingesting the substance. If contact or exposure occurs, it is recommended to wash the affected area thoroughly with soap and water and seek medical attention if necessary. It is essential to work in a well-ventilated area when using 1-Phenylethanol and to store it in a cool, dry place away from incompatible materials. In case of a spill, proper cleanup procedures should be followed to prevent environmental contamination or health hazards.

🔬 Potential Research Directions

Research on 1-Phenylethanol, a versatile aromatic compound, could explore its applications in the pharmaceutical industry. Studies could investigate its potential as an anti-inflammatory agent or its efficacy in the treatment of neurological disorders.

Additionally, research could focus on the chemical synthesis of 1-Phenylethanol in order to improve its production efficiency and purity. This could involve developing novel synthetic routes or optimizing existing methods to enhance yield and minimize byproducts.

Furthermore, investigations into the biological activities of 1-Phenylethanol could shed light on its potential as an antimicrobial or antioxidant agent. Understanding its mechanism of action and identifying its molecular targets could pave the way for the development of new therapeutic agents.

One closely related compound to 1-Phenylethanol is 2-Phenylethanol, which differs by the position of the hydroxyl group on the phenyl ring. This compound shares the same molecular formula as 1-Phenylethanol (C8H10O), but the arrangement of atoms in the molecule causes differences in physical and chemical properties. 2-Phenylethanol is also known as β-phenylethanol due to the position of the hydroxyl group on the carbon chain.

Another similar compound to 1-Phenylethanol is Benzyl alcohol, which has a benzene ring attached directly to the hydroxyl group. Benzyl alcohol has the chemical formula C7H8O, and like 1-Phenylethanol, it is commonly used in fragrances and as a solvent. Both compounds have a similar aromatic scent due to the presence of the benzene ring in their structures. However, Benzyl alcohol is more commonly used in industrial applications due to its lower cost and availability.

A third compound that shares similarities with 1-Phenylethanol is Cinnamyl alcohol, which contains a longer carbon chain attached to the phenyl ring. Cinnamyl alcohol has the molecular formula C9H10O and is commonly found in cinnamon bark oil. Like 1-Phenylethanol, Cinnamyl alcohol has a pleasant odor and is used in fragrances and flavorings. The longer carbon chain in Cinnamyl alcohol gives it slightly different physical and chemical properties compared to 1-Phenylethanol, but both compounds belong to the same chemical family.

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