1-Phenyl-1,2-propanedione, also known as benzoylacetone, is a compound used in various everyday products. It is commonly found in cosmetics, perfumes, and flavorings due to its pleasant scent. Additionally, this compound plays a key role in the synthesis of pharmaceuticals and agrochemicals, making it an essential ingredient in the production of many consumer goods. Overall, 1-Phenyl-1,2-propanedione has a significant impact on everyday life through its contributions to numerous industries and products.
Table of Contents:
- 💡 Commercial Applications
- ⚗️ Chemical & Physical Properties
- 🏭 Production & Procurement
- ⚠️ Safety Considerations
- 🔬 Potential Research Directions
- 🧪 Related Compounds
💡 Commercial Applications
1-Phenyl-1,2-propanedione, commonly known as benzylacetone, has various commercial and industrial applications. It is used as a fragrance ingredient in perfumes and cosmetics due to its sweet, floral odor. In the industrial sector, 1-Phenyl-1,2-propanedione is used as a chemical intermediate in the production of pharmaceuticals, agrochemicals, and other organic compounds.
In terms of drug and medication applications, 1-Phenyl-1,2-propanedione is used as a precursor in the synthesis of various pharmaceuticals. It can be found in certain medications as an active ingredient or as a chemical building block. Research has shown its potential use in the treatment of certain medical conditions, although further studies are needed to fully explore its medicinal properties.
⚗️ Chemical & Physical Properties
1-Phenyl-1,2-propanedione, also known as benzoylacetone, is a pale yellow crystalline solid with a strong aromatic odor. The compound is commonly used in the synthesis of various organic compounds due to its distinctive smell and appearance.
This compound has a molar mass of 164.2 g/mol and a density of 1.11 g/cm³. In comparison to common food items, 1-Phenyl-1,2-propanedione has a higher molar mass and density, making it more dense and heavy than most food substances.
1-Phenyl-1,2-propanedione has a melting point of 41-43°C and a boiling point of 302-304°C. Compared to common food items, this compound has significantly higher melting and boiling points, indicating a higher level of thermal stability.
1-Phenyl-1,2-propanedione is insoluble in water but soluble in organic solvents. It has a low viscosity, making it easily pourable. In contrast, common food items are typically more soluble in water and may have higher viscosity levels.
🏭 Production & Procurement
1-Phenyl-1,2-propanedione, also known as benzylacetone, is primarily produced through the Friedel-Crafts acylation reaction. This reaction involves the acylation of benzene using an acyl chloride in the presence of a Lewis acid catalyst. The resulting product is then subjected to further purification steps to obtain pure 1-Phenyl-1,2-propanedione.
In terms of procurement and transportation, 1-Phenyl-1,2-propanedione can be purchased from various chemical suppliers around the world. The compound is typically supplied as a solid or liquid and is often packaged in glass or plastic containers to ensure its safe transportation. Depending on the quantity required, 1-Phenyl-1,2-propanedione can be shipped via ground or air freight to its destination.
It is important to note that 1-Phenyl-1,2-propanedione is a hazardous chemical and should be handled with care. Proper safety precautions, such as the use of personal protective equipment (PPE) and proper ventilation, should be taken when working with this compound. Additionally, proper labeling and documentation should accompany the shipment of 1-Phenyl-1,2-propanedione to ensure regulatory compliance and safe handling throughout its transportation.
⚠️ Safety Considerations
Safety considerations for handling 1-Phenyl-1,2-propanedione include ensuring proper ventilation in the working area to prevent inhalation of vapors. Personal protective equipment such as gloves, goggles, and lab coat should be worn to minimize skin and eye contact with the chemical. It is important to store 1-Phenyl-1,2-propanedione in a cool, dry place away from sources of ignition and incompatible materials to prevent fire hazards.
Hazard statements for 1-Phenyl-1,2-propanedione include “Causes skin irritation” and “May cause an allergic skin reaction.” Additionally, it is classified as harmful if swallowed, causing damage to organs through prolonged or repeated exposure. This chemical may also be harmful if inhaled, leading to respiratory irritation and other potential health effects.
Precautionary statements for handling 1-Phenyl-1,2-propanedione include wearing protective gloves, eye protection, and face protection to prevent skin and eye contact. It is recommended to wash hands thoroughly after handling and before eating, drinking, or using the restroom. In case of skin irritation or allergic reaction, seek medical advice and attention. Additionally, store this chemical in a well-ventilated area away from heat sources and incompatible materials.
🔬 Potential Research Directions
1-Phenyl-1,2-propanedione, often referred to as PPD, has shown potential as a versatile compound for research in various fields. One potential research direction could include exploring its applications in organic synthesis, particularly in the development of new chemical reactions and methodologies.
Additionally, PPD could be further studied for its potential therapeutic properties. Research could focus on investigating its biological activities, such as its potential as an antioxidant, antimicrobial agent, or anti-inflammatory compound.
Moreover, the structural features of 1-phenyl-1,2-propanedione suggest possible applications in materials science. Research in this area could explore its potential as a building block for the synthesis of new materials with unique properties, such as in the development of polymers or nanomaterials.
🧪 Related Compounds
1-Phenyl-1,2-propanedione belongs to a class of compounds known as arylalkanones. These compounds contain an aromatic ring attached to an alkane chain with a ketone functional group. One similar compound is 1-(4-methylphenyl)-1,2-propanedione, which is structurally analogous to 1-phenyl-1,2-propanedione but has a methyl group attached to the phenyl ring.
Another related compound is 1-(4-chlorophenyl)-1,2-propanedione. This compound also shares the same basic structure as 1-phenyl-1,2-propanedione but has a chlorine atom substituted on the phenyl ring. These compounds are commonly used in organic synthesis and pharmaceutical research due to their versatile reactivity and diverse applications.
