1-Indanol, a chemical compound primarily used in industrial applications such as the production of fragrances and pharmaceuticals, plays a crucial role in everyday life. It is commonly found in household products like perfumes, lotions, and cleaning agents, contributing to their distinct scents. Additionally, 1-Indanol is utilized in the manufacturing of medications and drugs, highlighting its significance in the pharmaceutical sector. This compound’s versatility and importance in various industries demonstrate its relevance to consumers’ daily experiences, despite its behind-the-scenes presence in numerous products.
Table of Contents:
- 💡 Commercial Applications
- ⚗️ Chemical & Physical Properties
- 🏭 Production & Procurement
- ⚠️ Safety Considerations
- 🔬 Potential Research Directions
- 🧪 Related Compounds
💡 Commercial Applications
1-Indanol, or 1-Hydroxyindane, is a versatile compound with several commercial and industrial applications. It is commonly used as a fragrance ingredient in perfumes and cosmetics due to its pleasant aroma. Additionally, it is employed as a solvent in various chemical processes and as a precursor in the synthesis of pharmaceuticals and fine chemicals.
In the pharmaceutical industry, 1-Indanol has shown promising potential in drug and medication applications. It is being studied for its antiviral properties and its ability to inhibit certain enzymes involved in disease processes. Furthermore, its role as a building block for drug synthesis makes it a valuable compound in medicinal chemistry for creating new pharmaceuticals with improved efficacy and reduced side effects.
Overall, the commercial and industrial applications of 1-Indanol make it a valuable compound in various industries, ranging from fragrance and cosmetics to pharmaceuticals and fine chemicals. Its diverse properties and potential in drug development highlight its importance as a multifaceted compound with broad applications in the commercial and industrial sectors.
⚗️ Chemical & Physical Properties
1-Indanol, also known as indan-1-ol, is a colorless liquid that possesses a pleasant floral-like odor. It has a characteristic aromatic scent that is commonly described as sweet and slightly fruity.
With a molar mass of approximately 134.19 g/mol and a density of about 0.97 g/cm³, 1-Indanol is relatively light compared to common food items such as sugar (molar mass: 342.30 g/mol, density: 1.59 g/cm³) and salt (molar mass: 58.44 g/mol, density: 2.16 g/cm³).
The melting point of 1-Indanol is around -7.4°C, while its boiling point is approximately 190°C. In comparison, common food items like butter (melting point: 32°C, boiling point: 150°C) and olive oil (melting point: <-6°C, boiling point: 250-280°C) have different melting and boiling points. 1-Indanol is moderately soluble in water and exhibits a relatively low viscosity. Compared to common food items such as flour (insoluble in water, high viscosity) and sugar (highly soluble in water, low viscosity), 1-Indanol falls somewhere in between in terms of solubility and viscosity.
🏭 Production & Procurement
1-Indanol, also known as indan-1-ol, is typically produced through a multistep process involving the catalytic hydrogenation of indene. This reaction converts indene into 1-indanol by the addition of hydrogen in the presence of a catalyst. The resulting 1-indanol can then be purified and isolated for further use in various applications.
To procure 1-Indanol, one can typically obtain it from chemical suppliers that specialize in producing and distributing fine chemicals and intermediates. It is commonly available in both liquid and solid forms, depending on the purity and intended use of the compound. Once procured, 1-Indanol can be transported via standard chemical transportation methods, such as sealed containers or drums, to ensure its safe delivery to its intended destination.
The transportation of 1-Indanol must adhere to strict safety guidelines to prevent any potential hazards during transit. Specialized carriers equipped with appropriate handling equipment may be required to transport this compound due to its potential flammability and reactivity. Proper labeling and documentation are essential to comply with regulatory requirements and ensure the safe and secure transportation of 1-Indanol.
⚠️ Safety Considerations
Safety considerations for 1-Indanol should be taken seriously due to its potential hazards. 1-Indanol is classified as a flammable liquid and may form explosive mixtures with air. It can also cause irritation to the skin and eyes upon contact and may be harmful if ingested or inhaled. When working with 1-Indanol, it is important to use appropriate personal protective equipment such as gloves, goggles, and a lab coat to minimize the risk of exposure.
The hazard statements for 1-Indanol include “Highly flammable liquid and vapor,” “Causes skin and eye irritation,” and “Harmful if swallowed or inhaled.” These statements indicate the potential dangers associated with exposure to 1-Indanol and highlight the importance of taking proper precautions when handling this chemical. It is crucial to follow safety protocols and guidelines to prevent accidents and minimize the risk of harm.
Precautionary statements for 1-Indanol include “Keep away from heat/sparks/open flames/hot surfaces,” “Wear protective gloves/eye protection/face protection,” and “IF IN EYES: Rinse cautiously with water for several minutes.” These statements emphasize the necessary precautions that should be taken when working with 1-Indanol to ensure the safety of individuals handling the chemical. It is essential to store 1-Indanol properly, handle it with care, and follow established safety procedures to reduce the risk of accidents and exposure.
🔬 Potential Research Directions
One potential research direction for 1-Indanol is its use as a precursor in the synthesis of various pharmaceutical compounds due to its versatile chemical properties. Researchers may explore the development of new synthetic methods and optimizations to enhance the efficiency and yield of these processes.
Another research avenue could involve investigating the potential biological activities and pharmacological properties of 1-Indanol and its derivatives. This could include exploring its anti-inflammatory, antioxidant, or antimicrobial properties, among others, to uncover potential applications in the field of medicine and drug discovery.
Furthermore, the study of the environmental fate and biodegradability of 1-Indanol could be of interest, especially in the context of its potential use as a chemical intermediate in various industries. Understanding its behavior in the environment and its impact on ecosystems can provide valuable insights for sustainable and environmentally friendly practices in the chemical industry.
🧪 Related Compounds
One similar compound to 1-Indanol is 2-Indanol, which is structurally similar but with a hydroxyl group located at the second carbon atom rather than the first. This compound retains the bicyclic structure of indanol, contributing to similar physical and chemical properties. The presence of the hydroxyl group allows for potential hydrogen bonding interactions, affecting its solubility and reactivity.
Another compound related to 1-Indanol is 3-Indanol, where the hydroxyl group is located at the third carbon atom of the indane ring system. Like 2-Indanol, this compound exhibits comparable properties to 1-Indanol due to the shared structural features. The position of the hydroxyl group can influence the compound’s stability, reactivity, and interactions with other molecules or solvents.
One more compound of interest is 1-Indanone, where the hydroxyl group in 1-Indanol is replaced by a carbonyl group. This alteration results in a ketone function, changing the compound’s reactivity and chemical behavior. Despite this difference, 1-Indanone still maintains the bicyclic structure of indanol, leading to similarities in some properties while showing distinct differences in others.