1-Butanol

1-Butanol, a type of alcohol, holds significant relevance in everyday life due to its versatile nature and applications. Commonly used as a solvent in various industries, including pharmaceuticals, cosmetics, and cleaning products, 1-Butanol plays a crucial role in the formulation of paints, coatings, and adhesives. Moreover, it is utilized in the production of fragrances, flavors, and food additives, contributing to the enhancement of consumer goods. Additionally, this compound serves as a fuel additive and intermediate in the synthesis of chemicals, highlighting its importance in modern society.

Table of Contents:

💡 Commercial Applications

1-Butanol, also known as n-butyl alcohol, has various commercial and industrial applications. It is commonly used as a solvent in industries such as textiles, paints, coatings, and adhesives. In addition, 1-Butanol is utilized as a precursor in the production of other chemicals such as butyl acetate and butyl glycol.

In the pharmaceutical industry, 1-Butanol is employed in the manufacture of certain drugs and medications. It is used as a solvent in the formulation of various pharmaceutical products, including antibiotics, hormones, and vitamins. Additionally, 1-Butanol is used as an intermediate in the synthesis of pharmaceutical compounds for treating various medical conditions.

Overall, 1-Butanol plays a crucial role in both commercial and industrial sectors due to its properties as a versatile solvent and intermediary chemical compound. Its applications in pharmaceutical manufacturing highlight its importance in the production of medications that are essential for human health and well-being.

⚗️ Chemical & Physical Properties

1-Butanol, also known as n-butanol, is a colorless liquid with a strong, distinct odor resembling that of alcohol or bananas. It is commonly used as a solvent and in the production of various chemicals.

With a molar mass of approximately 74.12 g/mol and a density of about 0.81 g/cm³, 1-Butanol is lighter than water. It is comparable in molar mass to common household items such as acetone and isopropyl alcohol, but denser than these substances.

1-Butanol has a melting point of around -90°C and a boiling point of around 118°C. These values are higher compared to common household items like water and ethanol. The higher melting and boiling points of 1-Butanol make it a valuable solvent in various applications.

1-Butanol is slightly soluble in water, with a solubility of around 7g per 100 mL of water. It has a relatively high viscosity compared to water, making it less viscous than substances like honey. The solubility and viscosity of 1-Butanol make it a versatile solvent for different industrial processes.

🏭 Production & Procurement

1-Butanol, also known as n-butanol or butyl alcohol, is primarily produced through the catalytic hydrogenation of butanal or butyraldehyde. This reaction involves the addition of hydrogen gas to the aldehyde group, resulting in the formation of 1-Butanol.

Once produced, 1-Butanol can be procured through various methods. It is commonly available for purchase from chemical suppliers in bulk quantities for industrial use. Additionally, 1-Butanol can also be synthesized in laboratories for research purposes by chemists and scientists.

In terms of transportation, 1-Butanol is typically stored and shipped in sealed containers to prevent exposure to air and moisture. It is commonly transported using specialized tanker trucks or railcars for large quantities, while smaller amounts can be shipped in drums or containers. Proper labeling and handling procedures must be followed to ensure safe transportation and use of 1-Butanol.

⚠️ Safety Considerations

Safety considerations for 1-Butanol include its flammability as a liquid and vapor, as well as its potential for causing skin irritation and eye irritation upon contact. It is important to handle 1-Butanol with care, using proper personal protective equipment such as gloves and goggles to prevent exposure. Additionally, proper ventilation should be utilized when working with 1-Butanol to minimize inhalation risks.

In terms of pharmacology, 1-Butanol is a primary alcohol that can be metabolized by the body through oxidation. It is primarily metabolized in the liver, where it is converted into butyric acid before being further metabolized into carbon dioxide and water. The metabolism of 1-Butanol can lead to the production of reactive oxygen species, which can contribute to oxidative stress in cells.

The hazard statements for 1-Butanol include its classification as a flammable liquid and its potential for causing skin and eye irritation. It is also classified as harmful if swallowed or if inhaled, and may cause respiratory irritation. Additionally, prolonged or repeated exposure to 1-Butanol can lead to damage to organs such as the liver and kidneys.

Precautionary statements for 1-Butanol include avoiding direct skin contact and eye contact, as well as using proper ventilation to minimize inhalation risks. It is important to keep 1-Butanol away from heat sources and open flames, as well as to store it in a well-ventilated area away from incompatible materials. In case of ingestion, medical attention should be sought immediately, and the individual should not induce vomiting unless directed by medical personnel.

🔬 Potential Research Directions

One potential research direction for 1-Butanol lies in investigating its use as a biofuel. Researchers may explore the efficiency and environmental impact of 1-Butanol as a renewable alternative to traditional fossil fuels.

Another avenue for research on 1-Butanol involves its potential applications in the pharmaceutical industry. Studies could be conducted to examine the compound’s medicinal properties and its effectiveness in various drug formulations.

Further research on 1-Butanol could focus on its potential as a precursor for various chemical compounds. Scientists may explore its reactivity and versatility in organic synthesis, leading to the development of new materials and substances.

One similar compound to 1-Butanol based upon molecular structure is 2-Butanol, also known as sec-butanol. This compound has a similar molecular formula of C4H10O, but differs in the location of the hydroxyl group on the second carbon atom rather than the first. Due to this difference in structure, 2-Butanol exhibits different physical and chemical properties compared to 1-Butanol, making it an important compound for various industrial applications.

Another compound closely related to 1-Butanol is isobutanol, also known as 2-methyl-1-propanol. Isobutanol has the same molecular formula of C4H10O as 1-Butanol, but differs in the arrangement of atoms within the molecule. Isobutanol contains a branched structure with a methyl group on the second carbon atom, leading to distinctive properties that differentiate it from 1-Butanol. This compound is commonly used as a solvent, fuel additive, and in the production of chemicals such as esters and plasticizers.

A third similar compound to 1-Butanol based upon molecular structure is tert-Butanol, also known as 2-methyl-2-propanol. Like the previous examples, tert-Butanol shares the molecular formula C4H10O with 1-Butanol, but possesses a distinct structure due to the presence of a tert-butyl group on the carbon atom bearing the hydroxyl group. This compound exhibits unique physical and chemical properties, making it valuable in applications ranging from solvents and intermediates in chemical synthesis to fuel additives and pharmaceuticals.

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