1-Bromo-3-chloropropane 

1-Bromo-3-chloropropane, a chemical compound used in industries such as pharmaceuticals, agriculture, and manufacturing, plays a significant role in everyday life. It is commonly employed as a solvent, a chemical intermediate, and a reagent in various processes. This compound’s versatility and utility make it essential for a wide range of applications, from the production of pharmaceuticals to the synthesis of agrochemicals. Its presence in everyday products underscores its importance in modern society.

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💡  Commercial Applications

1-Bromo-3-chloropropane, also known as 1,3-dibromochloropropane, is primarily used as an intermediate in the synthesis of pharmaceuticals and agrochemicals. In the commercial and industrial sectors, this compound is commonly used in the production of flame retardants, pesticides, and rubber chemicals.

Due to its ability to alkylate nucleophilic sites on proteins and DNA, 1-Bromo-3-chloropropane has found applications in biological research and drug development. This compound is often used as a chemical reagent in the synthesis of certain medications and as a starting material in the preparation of pharmacologically active compounds.

Although primarily known for its role in commercial and industrial processes, 1-Bromo-3-chloropropane has also shown promise in medicinal contexts. Some studies have explored the potential therapeutic benefits of this compound in the treatment of certain diseases, such as cancer, due to its ability to interact with cellular targets in a specific and controlled manner.

⚗️  Chemical & Physical Properties

1-Bromo-3-chloropropane is a colorless liquid with a pungent, sweet odor. It is commonly used as a chemical intermediate in organic synthesis.

The molar mass of 1-Bromo-3-chloropropane is 157.45 g/mol, and its density is 1.625 g/cm³. Compared to common food items, such as sugar with a molar mass of about 342.30 g/mol and a density of 1.59 g/cm³, 1-Bromo-3-chloropropane is lighter in molar mass but denser.

1-Bromo-3-chloropropane has a melting point of -45°C and a boiling point of 158°C. In comparison, common food items like butter have melting points ranging from 32-35°C, and water boils at 100°C, indicating 1-Bromo-3-chloropropane has higher melting and boiling points.

1-Bromo-3-chloropropane is insoluble in water and exhibits a higher viscosity compared to common food items like vinegar, which is soluble in water and has lower viscosity. Its lack of solubility and higher viscosity make it less suitable for culinary uses.

🏭  Production & Procurement

1-Bromo-3-chloropropane, also known as 1-bromo-3-chloropropane, is typically produced through the reaction between 1,3-dichloropropane and sodium bromide in the presence of sulfuric acid. This reaction results in the substitution of one chlorine atom with a bromine atom, yielding the desired product.

The procurement of 1-Bromo-3-chloropropane can be achieved through various chemical suppliers and manufacturers. It is commonly available in both bulk quantities and smaller volumes for research purposes. Transportation of this compound is typically done in sealed containers to prevent leakage and exposure to moisture or other reactive substances.

When procuring 1-Bromo-3-chloropropane, it is essential to ensure that all safety precautions are followed during handling and transportation. This compound should be stored in a cool, dry place away from direct sunlight and sources of ignition. It is crucial to consult the material safety data sheet (MSDS) for handling guidelines and proper disposal methods.

⚠️  Safety Considerations

Safety considerations for 1-Bromo-3-chloropropane include its potential to cause irritation and damage to the respiratory system, skin, and eyes upon exposure. This compound is also flammable and may release harmful gases when heated, posing a fire hazard. Proper ventilation and personal protective equipment should be used when handling 1-Bromo-3-chloropropane to minimize risks to health and safety.

Hazard statements for 1-Bromo-3-chloropropane include “Causes skin irritation,” “Causes serious eye irritation,” and “May cause respiratory irritation.” These statements serve as warnings about the potential health hazards associated with exposure to this compound. It is important to follow appropriate safety measures and precautions to prevent adverse effects on the skin, eyes, and respiratory system.

Precautionary statements for 1-Bromo-3-chloropropane recommend avoiding direct contact with the compound, using suitable protective clothing and equipment, and ensuring adequate ventilation in the work area. It is also advised to wash hands thoroughly after handling 1-Bromo-3-chloropropane and seek medical attention in case of exposure or if experiencing symptoms of irritation. Following these precautions can help minimize the risks associated with handling this chemical compound.

🔬  Potential Research Directions

Research on 1-Bromo-3-chloropropane could focus on its toxicity and environmental impact, investigating its potential as a harmful substance in various ecosystems and its effects on human health.

Furthermore, studies may explore the synthesis and production methods of 1-Bromo-3-chloropropane, examining the efficiency and feasibility of different approaches to obtain this chemical compound.

Additionally, research could delve into the potential applications of 1-Bromo-3-chloropropane in industry and technology, including its use as a reactant in organic synthesis or as a starting material for the production of other chemicals.

One similar compound to 1-Bromo-3-chloropropane is 1-Chloro-3-bromopropane. This compound is also a halogenated alkane with a bromine and chlorine atom attached to a three-carbon chain. The positioning of the bromine and chlorine atoms is reversed in comparison to 1-Bromo-3-chloropropane.

Another compound with a similar molecular structure to 1-Bromo-3-chloropropane is 1-Bromo-2-chloropropane. In this compound, the bromine and chlorine atoms are attached to adjacent carbons on the three-carbon chain. This change in positioning alters the physical and chemical properties of the compound compared to 1-Bromo-3-chloropropane.

Additionally, 2-Bromo-3-chloropropane is a compound closely related to 1-Bromo-3-chloropropane. In this compound, the bromine and chlorine atoms are attached to carbons two and three of the three-carbon chain. The altered positioning of the halogen atoms leads to variations in the compound’s reactivity and potential uses.

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