1-Bromo-2-naphthol, a chemical compound with various applications in the fields of pharmaceuticals, cosmetics, and dyes, plays a significant role in our everyday lives. This compound is utilized in the synthesis of drugs, such as antiseptics and antifungal agents, as well as in the production of hair dyes and colorants. Additionally, 1-Bromo-2-naphthol is used in scientific research and academic studies, contributing to advancements in various industries that impact our daily interactions and experiences. Its multifaceted properties make it an essential component in many products and processes that we encounter on a regular basis.
Table of Contents:
- 💡 Commercial Applications
- ⚗️ Chemical & Physical Properties
- 🏭 Production & Procurement
- ⚠️ Safety Considerations
- 🔬 Potential Research Directions
- 🧪 Related Compounds
💡 Commercial Applications
1-Bromo-2-naphthol, also known as BN, finds commercial and industrial applications as a chemical intermediate in the synthesis of dyes, pharmaceuticals, and agrochemicals. It is utilized in the production of vat dyes, which are widely used in textile industries for coloration of fabrics. Additionally, 1-Bromo-2-naphthol is employed in the manufacturing of pharmaceuticals and agrochemicals due to its reactivity and functional groups.
In the realm of drug and medication applications, 1-Bromo-2-naphthol serves as a significant building block in the synthesis of various pharmaceutical compounds. Its versatile chemical structure allows for modification and functionalization, enabling the creation of novel drug candidates with potential therapeutic properties. Furthermore, 1-Bromo-2-naphthol may be utilized in the pharmaceutical industry for the preparation of prodrugs, which are inactive compounds that are converted into active drugs within the body through metabolic processes.
⚗️ Chemical & Physical Properties
1-Bromo-2-naphthol is a white to light yellow solid with a faint odor. It is sparingly soluble in water and is commonly used as a reagent in organic synthesis.
The molar mass of 1-Bromo-2-naphthol is approximately 223.13 g/mol, with a density of about 1.6 g/cm³. In comparison, common food items such as sucrose and table salt have molar masses ranging from 342.30 g/mol to 58.44 g/mol, and densities ranging from 1.587 g/cm³ to 2.165 g/cm³.
1-Bromo-2-naphthol has a melting point of around 130°C and a boiling point of approximately 335°C. When compared to common food items like butter and sugar, which have melting points ranging from 32°C to 186°C and boiling points ranging from 320°C to 871°C, 1-Bromo-2-naphthol falls within a similar range.
1-Bromo-2-naphthol is slightly soluble in water and has a moderate viscosity. This contrasts with common food items such as sugar and salt, which are highly soluble in water and typically have low viscosities.
🏭 Production & Procurement
1-Bromo-2-naphthol is produced through the bromination of 2-naphthol, a process that involves treating 2-naphthol with a brominating agent such as hydrogen bromide or bromine. This reaction results in the substitution of a hydrogen atom with a bromine atom on the 1-position of the naphthol molecule, yielding 1-Bromo-2-naphthol as the final product.
The procurement of 1-Bromo-2-naphthol typically involves purchasing the compound from chemical suppliers or manufacturers that specialize in the production of aromatic bromo compounds. It is commonly available in both liquid and solid forms, with the solid form typically being easier to handle and transport. Given the compound’s potential hazards and reactivity, proper precautions should be taken during its transportation, such as using appropriate packaging and labeling to ensure safe handling by personnel and minimize the risk of accidents.
Transporting 1-Bromo-2-naphthol may involve using dedicated containers that are specifically designed for storing and transporting hazardous chemicals. Additionally, the compound should be kept away from sources of ignition, incompatible materials, and extreme temperatures to prevent any potential hazards during transportation. It is important to adhere to regulatory guidelines and safety standards when transporting 1-Bromo-2-naphthol to ensure compliance with legal requirements and prevent any environmental or health risks.
⚠️ Safety Considerations
Safety considerations for 1-Bromo-2-naphthol should be taken seriously due to its hazardous properties. It is important to wear appropriate personal protective equipment when handling this compound, such as gloves, goggles, and a lab coat. Additionally, 1-Bromo-2-naphthol should only be used in a well-ventilated area to prevent inhalation of fumes.
The hazard statements for 1-Bromo-2-naphthol include “H302: Harmful if swallowed,” “H315: Causes skin irritation,” and “H319: Causes serious eye irritation.” These statements highlight the potential dangers associated with ingestion, skin contact, and eye contact with this compound. It is crucial to follow proper safety protocols when working with 1-Bromo-2-naphthol to avoid these hazards.
Precautionary statements for 1-Bromo-2-naphthol emphasize the importance of following safety guidelines to minimize risks. It is recommended to wash hands thoroughly after handling this compound and to dispose of any contaminated clothing or protective equipment properly. In case of skin contact, it is advised to rinse the affected area with water and seek medical attention if irritation persists. Additionally, it is crucial to store 1-Bromo-2-naphthol in a tightly sealed container away from heat and sources of ignition to prevent accidents.
🔬 Potential Research Directions
Research on 1-Bromo-2-naphthol, a derivative of naphthalene, has shown potential in various fields. As a brominated compound, it may serve as a precursor in the synthesis of other valuable chemicals, especially in the pharmaceutical and agrochemical industries. Its structural properties make it a promising candidate for studying organic reactions and mechanisms.
Further exploration of 1-Bromo-2-naphthol’s reactivity in various chemical transformations can lead to the discovery of novel synthetic routes and reactions. Understanding its behavior under different reaction conditions could provide insights into its potential applications in organic synthesis. Additionally, investigating its biocompatibility and toxicity profiles is essential for evaluating its potential for medicinal and biological applications.
Studies on the environmental fate and impact of 1-Bromo-2-naphthol are crucial for assessing its potential risks to ecosystems and human health. Research focusing on its degradation pathways and byproducts could aid in the development of strategies for its safe disposal and remediation. Moreover, investigations into its environmental persistence and bioaccumulation potential are necessary for regulatory purposes and risk assessment.
🧪 Related Compounds
One similar compound to 1-Bromo-2-naphthol based upon molecular structure is 1-Chloro-2-naphthol. This compound also consists of a naphthalene ring with a hydroxyl group at the 2-position, but with a chlorine atom instead of a bromine atom attached at the 1-position. This substitution of bromine with chlorine results in slightly different chemical properties and reactivity.
Another similar compound to 1-Bromo-2-naphthol is 1-Iodo-2-naphthol. Like the previously mentioned compound, 1-Iodo-2-naphthol shares the same naphthalene ring and hydroxyl group structure. However, in this case, iodine replaces bromine at the 1-position on the naphthalene ring. This substitution alters the physical and chemical properties of the compound compared to 1-Bromo-2-naphthol.
A third similar compound to 1-Bromo-2-naphthol based on molecular structure is 1-Methyl-2-naphthol. This compound retains the naphthalene ring structure and hydroxyl group at the 2-position, but with a methyl group attached at the 1-position instead of a halogen atom. The presence of the methyl group changes the chemical nature of the compound, leading to differences in properties and reactivity compared to 1-Bromo-2-naphthol.
