1-Benzyl-1,2,3,4-tetrahydroisoquinoline

1-Benzyl-1,2,3,4-tetrahydroisoquinoline, commonly known as BIQ, is a key compound in the pharmaceutical industry due to its potential therapeutic applications. It has shown promise in the treatment of conditions such as neurological disorders, addiction, and pain management. Its relevance to everyday life lies in its potential to improve the health and well-being of individuals through the development of new medications. Research on BIQ and its derivatives continues to be an area of interest in the medical community, as scientists aim to harness its properties for the benefit of society.

Table of Contents:

💡  Commercial Applications

1-Benzyl-1,2,3,4-tetrahydroisoquinoline, a compound with significant commercial and industrial applications, is commonly used in the synthesis of various pharmaceuticals and agrochemicals. Its versatile chemical structure allows for the production of complex molecules essential for the development of new drugs and crop protection products. Furthermore, this compound has shown promise in the field of organic chemistry as a valuable building block for the creation of diverse chemical compounds.

In the realm of drug and medication applications, 1-Benzyl-1,2,3,4-tetrahydroisoquinoline has been explored for its potential therapeutic properties. Research suggests that this compound may exhibit neuroprotective effects, making it a promising candidate for the treatment of neurological disorders such as Parkinson’s disease and Alzheimer’s disease. Additionally, its pharmacological properties have been studied for their potential anti-inflammatory and analgesic effects, indicating a broader scope of applications in the pharmaceutical industry. Overall, the medicinal potential of 1-Benzyl-1,2,3,4-tetrahydroisoquinoline makes it a promising target for further research and development in the field of drug discovery.

⚗️  Chemical & Physical Properties

1-Benzyl-1,2,3,4-tetrahydroisoquinoline, a compound commonly used in organic synthesis, appears as a colorless liquid with a faint odor. Its odor is described as mild and faint, making it relatively neutral in comparison to other chemical compounds.

With a molar mass of approximately 191.27 g/mol and a density of about 1.09 g/cm³, 1-Benzyl-1,2,3,4-tetrahydroisoquinoline is heavier than common food items like water (molar mass of 18.02 g/mol, density of 1.0 g/cm³) but lighter than sugar (molar mass of around 342.3 g/mol, density of 1.59 g/cm³). Its density is close to that of water, making it relatively similar in terms of weight to the human eye.

The compound has a melting point of about 52-56°C and a boiling point of around 274-275°C. In comparison to common food items, 1-Benzyl-1,2,3,4-tetrahydroisoquinoline has a higher melting point than butter (melting point of around 32-35°C) but a lower boiling point than olive oil (boiling point of around 300°C). Its melting and boiling points are within ranges commonly encountered in daily life.

1-Benzyl-1,2,3,4-tetrahydroisoquinoline exhibits low solubility in water and is relatively viscous. This compound is less soluble in water than salt but more so than oil. In terms of viscosity, it is thicker than water but less viscous than honey, placing it in a middle ground when compared to common food items.

🏭  Production & Procurement

1-Benzyl-1,2,3,4-tetrahydroisoquinoline, a compound frequently utilized in organic synthesis, is typically produced via the Pictet-Spengler reaction. This process involves the condensation of a benzaldehyde derivative with an amino alcohol, followed by cyclization to yield the desired tetrahydroisoquinoline product.

In terms of procurement, 1-Benzyl-1,2,3,4-tetrahydroisoquinoline can be acquired from various chemical suppliers or synthesized in-house by skilled organic chemists. Upon acquisition, the compound can be transported in sealed containers to maintain its integrity and prevent contamination during transit.

When transporting 1-Benzyl-1,2,3,4-tetrahydroisoquinoline, it is essential to adhere to proper safety protocols to mitigate any potential hazards associated with handling this compound. Additionally, ensuring that the compound is stored in a cool, dry environment away from direct sunlight can help maintain its stability and purity during transportation.

⚠️  Safety Considerations

Safety considerations for 1-Benzyl-1,2,3,4-tetrahydroisoquinoline must include general laboratory precautions such as wearing appropriate personal protective equipment (PPE) including gloves, lab coats, and safety goggles. In addition, proper ventilation should be ensured to prevent inhalation of vapors or dust. The compound should be handled in a fume hood to minimize exposure to potentially harmful substances.

Furthermore, it is important to conduct a risk assessment before working with 1-Benzyl-1,2,3,4-tetrahydroisoquinoline to determine the appropriate handling, storage, and disposal procedures. Emergency equipment such as eye wash stations and safety showers should be easily accessible in case of accidental exposure. It is advisable to have a well-equipped chemical spill kit on hand in the event of a spill.

Hazard statements for 1-Benzyl-1,2,3,4-tetrahydroisoquinoline may include phrases such as “causes skin irritation,” “may cause respiratory irritation,” and “harmful if swallowed.” These statements indicate the potential risks associated with the compound and emphasize the need for proper handling and storage procedures to minimize exposure and prevent adverse health effects. It is important to adhere to these hazard statements and take appropriate precautions when working with 1-Benzyl-1,2,3,4-tetrahydroisoquinoline to ensure personal safety.

Precautionary statements for 1-Benzyl-1,2,3,4-tetrahydroisoquinoline may include recommendations such as wearing protective gloves and eye protection, avoiding inhalation of vapors, and practicing good personal hygiene by washing hands thoroughly after handling the compound. It is also important to store the chemical in a cool, dry, well-ventilated area away from incompatible materials to prevent potential chemical reactions or spills. In case of accidental exposure, it is recommended to seek medical advice immediately and provide the relevant safety data sheet to healthcare professionals for proper treatment. Taking these precautionary measures can help minimize the risks associated with working with 1-Benzyl-1,2,3,4-tetrahydroisoquinoline and ensure a safe laboratory environment.

🔬  Potential Research Directions

One potential research direction for 1-Benzyl-1,2,3,4-tetrahydroisoquinoline is its potential use as a therapeutic agent in the treatment of neurological disorders. Studies have shown that this compound exhibits neuroprotective properties, making it a promising candidate for further investigation in the field of neuropharmacology.

Another area of interest for research on 1-Benzyl-1,2,3,4-tetrahydroisoquinoline is its role in modulating the activity of neurotransmitter systems in the brain. By investigating how this compound interacts with various neurotransmitter receptors, researchers can gain insights into its potential mechanisms of action and therapeutic applications in conditions such as depression and anxiety disorders.

Furthermore, exploring the synthesis and structure-activity relationships of derivatives of 1-Benzyl-1,2,3,4-tetrahydroisoquinoline could lead to the development of novel compounds with improved pharmacological properties. By modifying the chemical structure of the molecule, researchers can optimize its efficacy, selectivity, and safety profile, paving the way for the discovery of new drug candidates with enhanced therapeutic potential.

One similar compound to 1-Benzyl-1,2,3,4-tetrahydroisoquinoline based upon molecular structure is 1-Phenethyl-1,2,3,4-tetrahydroisoquinoline. In this compound, the benzene ring of benzyl has been replaced with a phenyl group, affecting the aromaticity and overall structure of the molecule. The presence of the phenethyl group can lead to different biological activities compared to 1-Benzyl-1,2,3,4-tetrahydroisoquinoline.

Another similar compound is 1-(4-Methoxybenzyl)-1,2,3,4-tetrahydroisoquinoline. In this molecule, a methoxy group has been added to the benzyl moiety, altering the electron density and steric hindrance around the benzyl group. This substitution can influence the compound’s interactions with biological targets and its pharmacological properties. The presence of the methoxy group can lead to changes in the compound’s solubility, metabolism, and binding affinity.

Furthermore, 1-(4-Fluorobenzyl)-1,2,3,4-tetrahydroisoquinoline is another example of a similar compound to 1-Benzyl-1,2,3,4-tetrahydroisoquinoline. Here, a fluorine atom has been introduced to the benzyl group, impacting the compound’s reactivity and physicochemical properties. The presence of the fluorine substituent can modify the compound’s lipophilicity and bioavailability, influencing its potential therapeutic applications. The introduction of a fluorine atom can also alter the compound’s pharmacokinetic properties and metabolic stability.

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