Compound Profile

1-Aminocyclopropanecarboxylic acid

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1-Aminocyclopropanecarboxylic acid, also known as ACC, is a crucial molecule in plant biology as it plays a pivotal role in the regulation of ethylene biosynthesis. Ethylene is a plant hormone that governs various processes like fruit ripening, flower senescence, and response to environmental stress. Consequently, ACC has significance in agricultural practices, influencing crop yields and quality. This compound’s relevance extends to everyday life through its impact on the availability and quality of fruits and vegetables, making it an important component in the global food supply chain.

Table of Contents:

💡 Commercial Applications

1-Aminocyclopropanecarboxylic acid, also known as ACC, has various commercial and industrial applications. It is commonly used in agriculture as a plant growth regulator to stimulate fruit ripening and flowering in crops. ACC is also utilized in the production of ethylene, a key chemical in the manufacturing of plastics and synthetic fibers.

In addition to its commercial and industrial uses, 1-Aminocyclopropanecarboxylic acid has significant drug and medication applications. ACC plays a crucial role in the pharmaceutical industry as a key intermediate in the synthesis of compounds used to regulate neurotransmitters in the brain. Furthermore, ACC is being explored for potential therapeutic applications in the treatment of neurological disorders and psychiatric conditions.

Overall, the diverse applications of 1-Aminocyclopropanecarboxylic acid highlight its importance across various industries, from agriculture and manufacturing to pharmaceuticals and medicine. The versatility and effectiveness of ACC in these different realms make it a valuable tool for enhancing plant growth, facilitating chemical reactions, and developing novel medications for a range of health conditions.

⚗️ Chemical & Physical Properties

1-Aminocyclopropanecarboxylic acid appears as a white crystalline solid with no distinctive odor.

With a molar mass of approximately 113.14 g/mol and a density of about 1.49 g/cm3, 1-Aminocyclopropanecarboxylic acid is heavier than common household items like sugar and salt in terms of molar mass and density.

1-Aminocyclopropanecarboxylic acid has a melting point of around 197-199°C and a boiling point of approximately 482°C. These values are higher than those of common household items like water and butter in terms of melting point and boiling point.

1-Aminocyclopropanecarboxylic acid is soluble in water and has a low viscosity. This puts it in contrast with common household items like oil and honey, which have lower solubility in water and higher viscosity.

🏭 Production & Procurement

1-Aminocyclopropanecarboxylic acid, also known as ACC, is typically produced through chemical synthesis methods. One common method involves the reaction of chloroacetonitrile with cyclopentadiene, followed by the addition of ammonia to form the desired product. This process allows for the controlled synthesis of ACC in a laboratory setting.

Procuring 1-Aminocyclopropanecarboxylic acid for research or industrial purposes can be achieved through various chemical suppliers or manufacturers. The compound is typically available in both liquid and solid forms, with different grades and purities depending on the intended application. Upon procurement, 1-Aminocyclopropanecarboxylic acid can be safely transported in sealed containers and stored according to recommended guidelines to ensure its stability and efficacy.

Transporting 1-Aminocyclopropanecarboxylic acid requires adherence to safety regulations and proper handling procedures. The compound should be packaged securely in compliant containers to prevent leakage or contamination during transit. Additionally, proper labeling and documentation of the shipment are essential to comply with regulatory requirements and ensure the safe delivery of 1-Aminocyclopropanecarboxylic acid to its intended destination.

⚠️ Safety Considerations

Safety considerations for 1-Aminocyclopropanecarboxylic acid should be taken seriously due to its potential hazards. When handling the compound, it is important to wear appropriate personal protective equipment such as gloves and goggles to prevent direct contact with the skin or eyes. It is also recommended to work in a well-ventilated area to minimize the risk of inhalation exposure. Proper storage of the chemical in tightly sealed containers away from incompatible materials is essential to avoid accidents.

In terms of pharmacology, 1-Aminocyclopropanecarboxylic acid is a potent inhibitor of ethylene biosynthesis in plants. This compound works by binding to the active site of the enzyme 1-aminocyclopropane-1-carboxylic acid synthase, thereby preventing the production of ethylene. Ethylene is a plant hormone responsible for various physiological processes such as ripening, senescence, and stress responses. By inhibiting ethylene synthesis, 1-Aminocyclopropanecarboxylic acid can extend the shelf life of fruits and vegetables and regulate plant growth and development.

Hazard statements for 1-Aminocyclopropanecarboxylic acid include “May be harmful if swallowed, inhaled, or absorbed through the skin” and “Causes serious eye irritation.” This compound can also cause skin irritation and respiratory irritation if proper precautions are not taken. In case of exposure, it is important to seek medical attention immediately and provide the medical personnel with the Safety Data Sheet for proper treatment.

Precautionary statements for 1-Aminocyclopropanecarboxylic acid include “Wear protective gloves/protective clothing/eye protection/face protection” and “Avoid breathing dust/fume/gas/mist/vapors/spray.” It is also recommended to wash thoroughly after handling and to dispose of the compound in accordance with local regulations. In case of a spill, it is important to contain the area and clean it up properly using suitable absorbent materials.

🔬 Potential Research Directions

One potential research direction for 1-Aminocyclopropanecarboxylic acid is its role in plant growth and development. This compound is known to regulate ethylene biosynthesis in plants, which plays a crucial role in processes such as fruit ripening, leaf senescence, and root growth.

Additionally, further investigation into the pharmacological properties of 1-Aminocyclopropanecarboxylic acid could provide insights into its potential medical applications. Studies have shown that this compound may have neuroprotective and antidepressant effects, making it a promising candidate for drug development.

Furthermore, exploring the environmental impact of 1-Aminocyclopropanecarboxylic acid is another avenue of research. As a precursor to the plant hormone ethylene, understanding the pathways and mechanisms by which this compound is synthesized and metabolized could have implications for agricultural practices and environmental sustainability.

One similar compound to 1-Aminocyclopropanecarboxylic acid is 2-Aminocyclopropanecarboxylic acid. In this compound, the amine group is located on the second carbon of the cyclopropane ring instead of the first carbon as in 1-Aminocyclopropanecarboxylic acid. This change in position of the amine group can lead to different chemical properties and reactivity compared to 1-Aminocyclopropanecarboxylic acid.

Another similar compound is Cyclopropanecarboxylic acid, a cyclic carboxylic acid without an amino group. The cyclopropane ring in this compound is larger than in 1-Aminocyclopropanecarboxylic acid, as it does not contain the additional amino group. Despite this difference, both compounds share the cyclopropane ring structure, which can play a significant role in their chemical behavior and interactions with other molecules.

A third similar compound is Aminoacetic acid, also known as glycine. This compound has a similar backbone structure to 1-Aminocyclopropanecarboxylic acid, with an amino and carboxylic acid group attached to the same carbon atom. However, Aminoacetic acid does not contain a cyclopropane ring like 1-Aminocyclopropanecarboxylic acid, which may affect its chemical properties and reactivity. Despite these structural differences, both compounds contain the key functional groups necessary for protein synthesis and other biological processes.

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