1-(4-Methylphenyl)ethanol, also known as p-ethyltoluene or para-methylphenylethanol, is a compound that is commonly used in the production of fragrance and flavor compounds. Its pleasant and floral aroma makes it a popular choice in perfumes, colognes, and scented products. Additionally, it is used in the food industry to enhance the flavor of certain products.
In everyday life, you may encounter this compound in perfumes, air fresheners, household cleaners, and even in certain food and beverage products. Its presence adds to the overall sensory experience and contributes to the pleasant aroma and taste of various products.
Table of Contents:
- 💡 Commercial Applications
- ⚗️ Chemical & Physical Properties
- 🏭 Production & Procurement
- ⚠️ Safety Considerations
- 🔬 Potential Research Directions
- 🧪 Related Compounds
💡 Commercial Applications
1-(4-Methylphenyl)ethanol, also known as p-methylphenethyl alcohol, finds extensive use in commercial and industrial applications. This compound serves as a valuable intermediate for the synthesis of fragrances, flavors, and pharmaceuticals. Its pleasant odor and stable properties make it a popular choice for use in perfumes, cosmetics, and personal care products.
In the commercial sector, 1-(4-Methylphenyl)ethanol is utilized as a versatile building block in the production of various chemicals. It is commonly employed in the manufacture of insect repellents, antiseptics, and disinfectants due to its antimicrobial properties. Additionally, this compound is utilized in the synthesis of specialty polymers, adhesives, and coatings for industrial applications.
In the realm of drug and medication applications, 1-(4-Methylphenyl)ethanol plays a crucial role as a key ingredient in the pharmaceutical industry. It is utilized in the synthesis of various medications, including analgesics, antipyretics, and antihistamines. Due to its ability to modify certain biological activities, this compound is incorporated into drug formulations to enhance therapeutic efficacy and reduce adverse effects.
⚗️ Chemical & Physical Properties
1-(4-Methylphenyl)ethanol is a colorless liquid with a faint floral odor. The compound is commonly used in perfumes and as a flavoring agent.
With a molar mass of approximately 136.18 g/mol and a density of about 1.013 g/cm³, 1-(4-Methylphenyl)ethanol is similar in molar mass to glucose but denser than water. This compound is often compared to common food items in terms of molar mass and density.
The melting point of 1-(4-Methylphenyl)ethanol is around 18-20°C, with a boiling point of approximately 221-223°C. These values are higher than those of sugar and salt, common food items often used as reference points for melting and boiling points.
1-(4-Methylphenyl)ethanol exhibits low solubility in water and has a relatively high viscosity. When compared to common food items, it shows differences in solubility and viscosity, which are important factors to consider in various applications.
🏭 Production & Procurement
1-(4-Methylphenyl)ethanol, also known as p-ethyltoluene, is primarily produced through a Friedel-Crafts alkylation reaction. This reaction involves the reaction of toluene with 4-methylstyrene in the presence of a Lewis acid catalyst, such as aluminum chloride. The resulting product is then subjected to a reduction reaction to yield 1-(4-Methylphenyl)ethanol.
The procurement of 1-(4-Methylphenyl)ethanol can be achieved through various means, including direct purchase from chemical suppliers or synthesis in a laboratory setting. This compound is typically transported in sealed containers, such as drums or bottles, to prevent exposure to air and moisture which could lead to degradation. Careful handling and storage of 1-(4-Methylphenyl)ethanol is essential to maintain its purity and stability during transportation.
In industrial settings, 1-(4-Methylphenyl)ethanol may be procured in bulk quantities for use in the production of pharmaceuticals, fragrances, and other specialty chemicals. Specialized shipping and handling procedures may be required for large-scale transportation of this compound to ensure compliance with safety regulations and to prevent any potential hazards. Additionally, proper documentation and labeling of containers containing 1-(4-Methylphenyl)ethanol are critical for tracking and traceability purposes.
⚠️ Safety Considerations
Safety considerations for 1-(4-Methylphenyl)ethanol must include proper handling procedures to avoid potential hazards. The compound should be stored in a cool, dry place away from sources of heat or ignition. Personal protective equipment, such as gloves and goggles, should be worn when handling 1-(4-Methylphenyl)ethanol to prevent skin and eye contact.
Hazard statements for 1-(4-Methylphenyl)ethanol include “Causes skin irritation” and “Causes serious eye irritation.” These statements indicate the potential risks associated with exposure to the compound. It is important to take appropriate measures to minimize contact with the skin and eyes when working with 1-(4-Methylphenyl)ethanol to avoid adverse effects.
Precautionary statements for 1-(4-Methylphenyl)ethanol include “Wear protective gloves/protective clothing/eye protection/face protection” and “IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.” These statements provide specific guidance on how to handle 1-(4-Methylphenyl)ethanol safely and what to do in case of exposure. Following these precautions is essential to minimize the risks associated with the compound.
🔬 Potential Research Directions
Potential research directions for 1-(4-Methylphenyl)ethanol include its pharmacological properties and potential medical applications. Researchers may investigate its effects on the central nervous system and its potential use as an analgesic or sedative.
Additionally, studies could focus on the synthesis and purification methods of 1-(4-Methylphenyl)ethanol to optimize its yield and purity. This research could lead to more efficient production processes and potentially lower costs for industrial applications.
Furthermore, investigations into the environmental impact of 1-(4-Methylphenyl)ethanol may be warranted, particularly regarding its degradation pathways and potential eco-toxicity. Understanding its behavior in the environment is crucial for assessing its overall safety and sustainability.
🧪 Related Compounds
One similar compound to 1-(4-Methylphenyl)ethanol is 1-(3-Methylphenyl)ethanol. This compound has a slightly different structure compared to 1-(4-Methylphenyl)ethanol, with the methyl group located on the 3-position of the phenyl ring instead of the 4-position. This change in positioning can impact the compound’s chemical and physical properties.
Another similar compound is 2-(4-Methylphenyl)ethanol. In this compound, the phenyl ring is attached to the ethyl group at the 2-position, rather than the 1-position as in 1-(4-Methylphenyl)ethanol. This change in positioning can result in differences in the compound’s reactivity and behavior in various chemical reactions.
Lastly, another similar compound is 1-(4-Ethylphenyl)ethanol. This compound shares a similar structure to 1-(4-Methylphenyl)ethanol, but with an ethyl group instead of a methyl group attached to the phenyl ring. This difference in side chain can lead to variations in the compound’s solubility, melting point, and other physical properties.